Gastaut syndrome
Role of rufinamide in the management of Lennox-Gastaut syndrome (childhood epileptic encephalopathy)
... Abstract: Rufinamide, a triazole derivative that is structurally distinct from currently marketed antiepileptic drugs (AEDs), is in development for the adjunctive treatment of Lennox-Gastaut syndrome (LGS) ...
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Few individuals with Lennox-Gastaut syndrome have autism spectrum disorder: a comparison with Dravet syndrome
... Background: Autism spectrum disorder (ASD) in epilepsy has been a topic of increasing interest, which in general occurs in 15 – 35% of the patients with epilepsy, more frequently in those with intellectual disability ...
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Treatment-resistant Lennox-Gastaut syndrome: therapeutic trends, challenges and future directions
... Lennox- Gastaut syndrome (LGS), this devastating epileptic encephalopathy remains one of the most treatment-resistant epilepsies across the age ...electroclinical syndrome and epileptic ...
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Lennox–Gastaut syndrome: impact on the caregivers and families of patients
... Abstract: Lennox–Gastaut syndrome (LGS) has a major impact on the health-related quality of life (HRQL) of the affected children as well as their caregivers. The primary caregiver in the family is generally ...
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<p>Adjunctive Rufinamide in Children with Lennox-Gastaut Syndrome: A Literature Review</p>
... Abstract: Lennox-Gastaut syndrome (LGS) is a severe, childhood-onset, developmental epileptic encephalopathy, with different etiologies and co-morbidities. Seizure treatment in LGS represents a major ...
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Lennox gastaut syndrome, review of the literature and a case report
... Lennox-Gastaut syndrome (LGS) is a catastrophic epilep- tic encephalopathy that consists of multiple types of gen- eralized seizures which often vary in their frequency over a period of ...The ...
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Clobazam as an adjunctive therapy in treating seizures associated with Lennox–Gastaut syndrome
... Lennox–Gastaut syndrome (LGS) is a devastating childhood epilepsy syndrome characterized by the occurrence of multiple types of seizures and cognitive ...
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Treating Lennox–Gastaut syndrome in epileptic pediatric patients with third-generation rufinamide
... Lennox–Gastaut syndrome (LGS) is a rare but debilitating pediatric epileptic encephalopathy characterized by multiple intractable seizure ...this syndrome, as well as the need for polytherapy in the ...
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Adjunctive use of electroconvulsive therapy in patients with Lennox-Gastaut syndrome and drug-resistant epilepsy: A pilot study
... For many years, investigators and physi- cians have addressed the problem of medically-refractory epilepsy by investigat- ing and developing new AEDs (11). How- ever, no study has demonstrated that the new AEDs have ...
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Comprehensive overview: efficacy, tolerability, and cost-effectiveness of clobazam in Lennox–Gastaut syndrome
... Lennox–Gastaut syndrome (LGS) in patients at least 2 years of age, although the medication has been available in countries around the world to treat epilepsy and anxiety disorders for many ...
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Dental Considerations of a 4-year-old Girl with Lennox-Gastaut Syndrome. Case Report and Literature Review
... We present the developmental, oral, clinical, radiographic findings and oral treatment of a 4-year- old girl presenting with Lennox-Gastaut syndrome (LGS), which is a severe disabling childhood epilepsy ...
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A VALIDATED REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY METHOD FOR SIMULTANEOUS DETERMINATION OF FIVE ANTIEPILEPTIC DRUGS USED IN THE TREATMENT OF LENNOX–GASTAUT SYNDROME IN THEIR PHARMACEUTICAL DOSAGE FORMS
... Lennox–Gastaut syndrome (LGS) is a severe form of childhood epileptic encephalopathy with multiple etiologies, whether genetic, structural, metabolic, or ...
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Long-term Outcome of Resective Epilepsy Surgery in Patients With Lennox-Gastaut Syndrome
... Early and intensive investigations to determine underlying focal etiology are important for deciding surgical candidates, and careful preoperative investigations can be used to stee[r] ...
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Lennox Gastaut Syndrome in Mitochondrial Disease
... West syndrome to LGS has been discussed extensively and is known to be performed at a nonsignificant ...West syndrome being more electrophysiologically ...
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Resective Pediatric Epilepsy Surgery in Lennox-Gastaut Syndrome
... We described here that resective pedi- atric epilepsy surgery for LGS with abundant generalized and multire- gional EEG abnormalities may be suc- cessful for selected patients with or ev[r] ...
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Update on the management of Lennox-Gastaut syndrome with a focus on rufinamide
... features are not present at the onset of the syndrome. Due to the heterogeneous causes, the diagnosis may be delayed or uncertain, at least initially. Some aspects of the seizure semiology can be confusing. For ...
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Rufinamide in patients with Lennox-Gastaut syndrome
... The safety and efficacy of rufinamide adjunctive therapy in adult and pediatric patients with LGS (aged 4–30 years, n = 139) were evaluated in a double-blind, randomized, placebo-cont[r] ...
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West Syndrome and Lennox-Gastaut Syndrome: A Survey of Natural History
... taut syndrome are characterized by their onset in infancy and early childhood, intractable seizures occurring almost daily, severe psychomotor retardation, and poor prog-.. nosis.[r] ...
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A Study on Diseases Affecting Litopenaeus vannamei Farming in Coastal Districts of Andhra Pradesh, India
... White Faeces Syndrome (WFS) is observed in all the districts of L. vannamei culture ponds (Fig. 3). Incidences of WFS were observed after 20 days of stocking of the PLs in culture ponds. WFS in shrimp arises with ...
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Significance of defecography and the role of rectocele in constipated patients
... Anorectal outlet obstruction is a form of chronic con- stipation in which pan-colonic transit time is normal but there is delayed transit in the rectosigmoid segment. Some of these patients have dilatation of the rectum ...
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