Gastric cancers
The overmethylated genes in Helicobacter pylori-infected gastric mucosa are demethylated in gastric cancers
... the gastric can- cerous and precancerous lesions has been found to be similar in the ...type gastric cancers tended to be overmethylated in the LOH-B cases and to be undermethylated in the LOH-H ...
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The gene-reduction effect of chromosomal losses detected in gastric cancers
... diffuse-type gastric cancers showed a bimodal dis- tribution for the number of chromosomal losses in con- sistent with a previous study ...of gastric cancer cells that were initially well- ...given ...
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Approach to Gastric Cancers
... of gastric wall or prevention of food flow in the stomach by the ...of gastric cancers are anorexia, weight loss, persistent indigestion, and ...area. Gastric cancer usually causes anemia as a ...
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Genomic profile analysis of diffuse type gastric cancers
... (P = 1.29 × 10 −2 ), including six somatic mutations (three missense, one nonsense, one frameshift, and one splice site mutations) that have not been reported previously, whereas only one missense mutation was found in ...
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Expression of Plakophilins (PKP1, PKP2, and PKP3) in Gastric Cancers
... In the twentieth century, the highest number of cancer related deaths worldwide was attributed to gastric can- cer, a disease with a dismal course and outcome [1]. Alterations of intercellular adhesion are ...
5
Genomic alterations and molecular subtypes of gastric cancers in Asians
... The high molecular heterogeneity of GCs, as demon- strated in genomic studies, further underscores the need for molecular subtyping of GCs to improve the prognosis, diagnosis, and treatment outcomes. Molecu- lar ...
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Non-familial juvenile polyposis of the stomach with gastric cancers: a case report
... only a polyp in the transverse colon, with a histopatho- logical diagnosis of adenoma. The clinical stage was T1a N0 M0 stage IA according to the Japanese Gastric Can- cer Association staging system (14th ...
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Identification and validation of genes involved in gastric tumorigenesis
... in gastric carcinomas and when downregulated by siRNA, it leads to decrease in cell proliferation, cell cycle arrest and suppressed tumour formation in nude mice ...eral cancers including pancreatic cancer ...
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Iron deficient erythropoiesis might play key role in development of anemia in cancer patients
... gastrointestinal cancers may have iron deficiency anemia due to chronic blood loss and therefore, the inclusion of gastric cancers in the biochemical data subset limits the strength of the previous ...
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Original Article TERT promoter mutation, telomere length, and TERT expression in gastric cancer
... in gastric cancers were ...of gastric cancers and associated with advanced cancers (P = ...of gastric cancer tended to show higher expression of TERT (P = ...to gastric ...
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MTA1 promotes proliferation and invasion in human gastric cancer cells
... in gastric cancer. MTA1 expression in 61 gastric cancer tissue and adjacent noncancerous tissues was analyzed by ...in gastric cancers, which contributes to malignant cell growth by ...
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Epigenomic and Functional Characterization of Junctophilin 3 (JPH3) as a Novel Tumor Suppressor Being Frequently Inactivated by Promoter CpG Methylation in Digestive Cancers
... Junctophilin (JPH) proteins stabilize junctional membrane complexes between plasma membrane and endoplasmic reticulum, also implicated in some human diseases. JPH3 mutations are linked to Huntington's disease-like 2 ...
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Identification of Glypican-3 as a potential metastasis suppressor gene in gastric cancer
... in gastric cancers, we stained 75 gastric tumors (41 adenocarcinomas and 34 signet ring cell carcinomas), 11 adjacent pre-cancerous tissues, and 12 normal gastric tissues with antibodies ...
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Comparison of Helicobacter pylori infection frequency in the cardia and distal esophageal cancer patients with healthy individuals
... cardia cancers does not increase, but this association entails the increased incidence of non-cardia gastric ...non-cardia gastric cancers in comparison to colon ...
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Gastric cancer: epidemiology, prevention, classification, and treatment
... Abstract: Gastric cancer is the second most common cause of cancer-related deaths in the world, the epidemiology of which has changed within last ...in gastric cancer incidence rates is the effect of the ...
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High-Level Clonal FGFR Amplification and Response to FGFR Inhibition in a Translational Clinical Trial.
... amplified cancers is ...that gastric cancers with high-level clonal FGFR2 amplification have a high response rate to the selective FGFR inhibitor AZD4547, whilst cancers with sub-clonal or ...
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Trend in incidence of gastric adenocarcinoma by tumor location from 1969–2004: a study in one referral center in Iran
... Adenocarcinoma of the upper and middle third of stom- ach shows an increasing trend during the last 30 years in Iran. Gastric cancers are the most common malignant neoplasm among Iranians [3,4]. They are ...
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Prognostic and clinicopathological significance of ubiquitin-specific protease 22 overexpression in cancers: evidence from a meta-analysis
... system cancers and the small number of studies focusing on other cancer types might weaken our conclusions; thus, additional studies of different cancers could be included in a future ...
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Original Article Hypermethylation of RASSF1A CpG insland is associated with esophageal squamous cell carcinoma in Kazakh patients
... human cancers, includ- ing 80 to 100% of small-cell lung cancer cell lines and tumors, 30 to 40% of non-small-cell lung cancer cell lines and tumors, 49 to 62% of breast cancer cell lines and tumors, 67 to 70% of ...
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Should every region use the same gastric cancer scanning and treatment approaches? let’s reconsider: a northeastern turkey example
... of gastric cancer and 2) the health facility responsible for referring each patients and the main presentation at ...of gastric cancer cases checked for the presence of ...
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