Gastroesophageal Junction
Gastroesophageal Junction Adenocarcinoma: A Study
... International Gastric Cancer association (IGCA) an agreement has been achieved for classification of adenocarcinomas arising in the area of the esophago–gastric junction .This classification is based on ...
109
<p>Clinical Evaluation of the Safety and Efficacy of Trifluridine/Tipiracil in the Treatment of Advanced Gastric/Gastroesophageal Junction Adenocarcinoma: Evidence to Date</p>
... gastroesophageal junction adenocarcinoma after one or two prior lines of therapy was enrolled. These patients received tri fl uridine and tipiracil at 35 mg/m 2 twice daily; there was also a cohort of six ...
7
Giant leiomyoma of the gastroesophageal junction: technique and results of endoscopic full-thickness resection
... Between October 2008 and December 2010, four consecutive patients with leiomyoma of the gastroesophageal junction were treated endoscopically at our institution. The standard preoperative examinations ...
5
Prevalence of human papillomavirus and Helicobacter pylori in esophageal and gastroesophageal junction cancer biopsies from a case–control study in Ethiopia
... and gastroesophageal junc- tion tumor tissue specimens as opposed to gastric ...the gastroesophageal junction, the anatomical proximity to cardia tissue may explain the presence of ...
10
<p>Effectiveness and Safety of Apatinib in Patients with Advanced or Metastatic Adenocarcinoma of Stomach or Gastroesophageal Junction: A Prospective Observation Study</p>
... or gastroesophageal junction with measurable lesions (spiral CT scan ≥ 10 mm); (3) patients with therapeutic indications, and no contraindication to ...
8
Evaluation of resection of the gastroesophageal junction and jejunal interposition (Merendino procedure) as a rescue procedure in patients with a failed redo antireflux procedure. A single-center experience
... the gastroesophageal junction with interpos- ition of a jejunal segment between the distal esophagus and the remnant stomach (Merendino procedure) has been used in various clinical situations, mainly in ...
8
Gastroesophageal junction Paneth cell carcinoma with extensive cystic and secretory features – case report and literature review
... Case presentation: A 70-year-old Caucasian male who initially presented in the emergency room due to upper gastrointestinal bleeding was subsequently found to have a submucosal nodule at gastroesophageal ...
6
Original Article The efficacy of molecular targeted agents in the treatment of gastroesophageal junction cancer: a systematic review and meta-analysis
... Abstract: During the past decades, several prospective trials have been conducted to assess the efficacy of mo- lecular targeted agents (MTAs) in the treatment of gastroesophageal junction (GEJ) carcinoma, ...
6
Histopathologic features of esophageal glands in the region of the gastroesophageal junction in Chinese patients with gastric cardiac cancer involving the esophagus
... Abstract: Esophageal glands (EGs) were implicated previously as a potential origin of carcinomas of the gastroesophageal junction (GEJ). The studies of histopathology on diseases in EGs, however, are ...
8
Epidemiology of Gastroesophageal Junction Adenocarcinoma in Kashmir India
... and Gastroesophageal junction adenocarcinoma (GEJAC) has rapidly increased; however, the degree of increment of EAC was less than that of the GEJAC (Walther C et al 2001) 3 ...GE junction carcinoma ...
6
Pertuzumab in combination with trastuzumab and chemotherapy for Chinese patients with HER2-positive metastatic gastric or gastroesophageal junction cancer: a subpopulation analysis of the JACOB trial
... GEJC: gastroesophageal junction cancer; HR: hazard ratio; OS: overall survival; IHC: immunohistochemistry; ISH: in situ hybridization; ITT: intention-to-treat; ECOG PS: Eastern Cooperative Oncology Group ...
10
Meningeal Carcinomatosis: A Metastasis from Gastroesophageal Junction Adenocarcinoma
... cited. Gastroesophageal adenocarcinoma is a malignant type of cancer, which can metastasize to multiple ...of gastroesophageal adenocarcinoma and carcinomatous ...primary gastroesophageal cancer at ...
5
Original Article The Columnar-lined Mucosa at the Gastroesophageal Junction in Non-Human Primates
... Many authors claim that the cardia mucosa is present at birth [5, 6, 8, 10, 12, 34, 35]. Other authors have challenged this notion [14-18, 35-42]. The controversy in recognizing the CM in humans as a separate ...
8
HER2 expression and relevant clinicopathological features in gastric and gastroesophageal junction adenocarcinoma in a Chinese population
... Gastric cancer (GC) is the fourth most commonly diag- nosed cancer and the second most common cause of cancer-related deaths worldwide [1]. It has been sug- gested that the incidence rate of gastroesophageal junc- ...
7
High expression of carbonic anhydrase IX is significantly associated with glandular lesions in gastroesophageal junction and with tumorigenesis markers BMI1, MCM4 and MCM7
... junction and distal esophagus damages squamous epithe- lium and causes columnar cell metaplasia. CA9 is a well- known hypoxic indicator and plays an important role in maintaining the intracellular pH despite ...
9
Tumor regression and survival after perioperative MAGIC-style chemotherapy in carcinoma of the stomach and gastroesophageal junction
... From March 2006 to December 2012 patients with stages II and III gastric and esophagogastric junction (EGJ) carcinomas underwent a perioperative MAGIC regimen chemotherapy at the Elche University Hospital and the ...
10
Phase II study of epirubicin, oxaliplatin and docetaxel combination in metastatic gastric or gastroesophageal junction adenocarcinoma
... This phase II study of triplet cytotoxic therapy for meta- static gastric or GEJ adenocarcinoma showed that the combination of epirubicin, oxaliplatin and docetaxel is an active and well[r] ...
6
Gastroesophageal junction adenocarcinoma displays abnormalities in homologous recombination and nucleotide excision repair
... Objective: Esophageal adenocarcinoma (EAC) continues to be a disease associated with high mortality. Among the factors leading to poor outcomes are innate resistance to currently available therapies, advanced stage at ...
10
Pembrolizumab for the treatment of patients with recurrent locally advanced or metastatic gastric or gastroesophageal junction cancer: an evidence-based review of place in therapy
... Abstract: Gastric and esopahgeal cancers account for the six most common causes of cancer death worldwide. Locally advanced resectable cancers have a 5-year life expectancy of 30%. Despite use of chemotherapy, median ...
13
Multinucleated stromal giant cells in the gastroesophageal junctional and gastric mucosa: a retrospective study
... GEJ: Gastroesophageal junction; GERD: Gastroesophageal reflux disease; HGD: High grade dysplasia; HSV: Herpes simplex virus; IM: Intestinal metaplasia; LGD: Low grade dysplasia; MSGCs: Multinucleated ...
5