GC cells
Correlation between chemosensitivity to anticancer drugs and telomerase reverse transcriptase mRNA expression in gastric cancer
... of GC samples to anticancer drugs using the MTT assay in 60 GC ...results, GC cells were more susceptible to CDDP and 5-FU than to ADM and MMC, which coincided with previous reports ...for ...
5
Novel role of miR-133a-3p in repressing gastric cancer growth and metastasis via blocking autophagy-mediated glutaminolysis
... tumor cells which make miRNAs themselves closely associ- ated with clinical features including tumor stage, lymphatic invasion and patient ...in GC remains largely ...in GC by means of affecting the ...
22
<p>MicroRNA Profile Identifies miR-6165 Could Suppress Gastric Cancer Migration and Invasion by Targeting STRN4</p>
... different GC cell lines (SGC-7901, HCG-27, AGS, and BGC-823) and normal gastric cell (GES) using RT-qPCR ...of GC cells turned out to be signi fi cantly lower ...
11
Mesothelin is a target of chimeric antigen receptor T cells for treating gastric cancer
... T cells have achieved re- markable success in acute lymphoblastic ...T cells to treat solid cancer [33, ...T cells M28z10 compared with the second-generation M28z CAR T ...T cells targeting ...
14
MiR-145-5p suppresses the proliferation, migration and invasion of gastric cancer epithelial cells via the ANGPT2/NOD_LIKE_RECEPTOR axis
... in GC by acting as a biomarker ...of GC cells through regulating ANGPT2 ...on GC cells has not been reported ...in GC cells, and miR-145-5p could target ANGPT2 mRNA to ...
11
Original Article High expression of ZBED1 affects proliferation and apoptosis in gastric cancer
... Abstract: Background: ZBED1 (zinc finger BED-type containing 1) is a transcription factor. However, its expression, role and clinical significance in cancer are unclear. The purpose of this study is to investigate the ...
7
<p>HNF1A-Induced lncRNA HCG18 Facilitates Gastric Cancer Progression by Upregulating DNAJB12 via miR-152-3p</p>
... promote GC cell ...in GC was fi rst discov- ...GC cells. In sum, these results demonstrated that HCG18 promoted GC pro- gression by acting as a ceRNA of miR-152-3p to upregu- late ...
12
<p>Long Non-Coding RNA BLACAT1 Promotes the Tumorigenesis of Gastric Cancer by Sponging microRNA-149-5p and Targeting KIF2A</p>
... of GC by enhancing ABCB1 protein expression through inhibiting ...of GC needs to be further ...of GC cells. 15 Notably, lncRNA GACAT1 increases GC cell growth, invasion and migration ...
12
Original Article MicroRNA-873 inhibits proliferation and induces apoptosis by targeting CXCL1 in gastric cancer
... of GC (including serum alpha fetal protein (AFP) level), tumor size and TNM ...HGC27 cells and induce apoptosis of HGC27 ...on GC cells with decreased cell proliferation and increased ...in ...
9
CPEB4 promotes growth and metastasis of gastric cancer cells via ZEB1-mediated epithelial–mesenchymal transition
... with GC. We found that CPEB4 expression was distinctly increased in GC primary lesion compared with matched normal ...in GC evolution and metas- ...in GC cells by regulating ...
13
Regulatory network of circRNA–miRNA–mRNA contributes to the histological classification and disease progression in gastric cancer
... GES-1 cells was amplified using primers 5-GTA TGG CCT CAC AAG TCT TG-3 and 5-CTG TAG TAC CGA GAT TGT AGA TAT G-3, and then the PCR product was purified by using Gel Extraction Kit (Omega Bio-tek, Doraville, GA, ...
14
<p>The Down-Regulation of lncRNA PCAT18 Promotes the Progression of Gastric Cancer via MiR-107/PTEN/PI3K/AKT Signaling Pathway</p>
... on GC growth in vivo. A nude mice model of GC was constructed by subcuta- neously injecting the GC cells into ...MGC-803 cells were transfected with pcDNA-PCAT18 and control plasmid, ...
15
<p>LncRNA NORAD Promotes Proliferation And Inhibits Apoptosis Of Gastric Cancer By Regulating miR-214/Akt/mTOR Axis</p>
... Currently, studies have found that a variety of long non-coding RNAs (lncRNAs) are involved in the growth, proliferation and apoptosis of GC cells, and can be used as potential targets for GC ...
11
<p>The novel lncRNA p4516 acts as a prognostic biomarker promoting gastric cancer cell proliferation and metastasis</p>
... in GC has become a major ...in GC, 25 and lncRNA UCA1 aug- mented the invasive and migratory capabilities of GC cells by regulating the expression of EMT-associated ...198 GC and paired ...
17
The role of microRNA-133b and its target gene FSCN1 in gastric cancer
... GC cells. We also demonstrated that knock down of FSCN1 can inhibit GC cell growth and invasion suggesting its oncogenic roles in ...suppressed GC cell proliferation, migration and invasion ...
12
The anti-apoptotic and prognostic value of fibroblast growth factor 9 in gastric cancer
... floating cells were harvested at different time points and washed with ...apoptotic cells was determined by nuclear staining and two-colour analysis with Annexin ...Briefly, cells were fixed with a ...
11
Transcription factor RUNX2 up-regulates chemokine receptor CXCR4 to promote invasive and metastatic potentials of human gastric cancer
... stem cells contributed to pancreatic cancer metastasis ...stage GC development through recruitment of stromal cells and establishment of progenitor niche to favor tumor growth ...tumor cells ...
14
Original Article MCM4 upregulation predicts poor prognosis in gastric cancer
... in GC was determined by using the ONCOMINE ...in GC patients was explore by using Kaplan-Meier plotter ...in GC tissues both in mRNA and protein ...in GC tissues and high MCM4 expression was ...
11
Afferent activity to necklace glomeruli is dependent on external stimuli
... cyclase GC-D. The axons of GC-D-expressing (GC-D+) neurons innervate 9–15 "necklace" glomeruli encircling the caudal main olfactory bulb ...for GC-D+ neurons include two natriuretic ...
5
Long Noncoding RNA MALAT1 Regulates Hepatocellular Carcinoma Growth Under Hypoxia via Sponging MicroRNA 200a
... HCC cells remains ...HCC cells by hypoxia, suggesting that miR-200a might be involved in the cancer progression of hypoxic ...Hep3B cells, indicating that miR-200a may participate in ...
8