General Anesthetics
Designing General Anesthetics That Have a Better Safety Profile
... General anesthetics possess characteristics that make them valuable for use dur- ing a wide variety of surgical procedures [1] [2] ...commonly-used general anesthetics produce adverse effects ...
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One-time Exposure to General Anesthetics Alters Nociceptive Response and Nucleotide Hydrolysis in Infant Rats
... of anesthetics [41]. General anesthetics are able to interact with a variety of neuronal systems, including the GABAergic, glycinergic, cholinergic, and glutamatergic systems ...
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General anesthetics protects against cardiac arrest-induced brain injury by inhibiting calcium wave propagation in zebrafish
... by general anesthetics such as midazolam or ketamine ...that general anesthetics pretreatment protects against cardiac arrest-induced brain injury by inhibiting calcium wave propagation in ...
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Selective inhibition of osmotic water flow by general anesthetics to toad urinary bladder
... bladders, the anesthetics do not inhibit cyclic AMP-stimulated water flow, consistent with an effect on vasopressin-responsive adenylate cyclase. The selectivity of the anesthetic- induced depression of water flow ...
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Light-Enabled Identification of the Neuronal Substrates of Alkylphenol Anesthetics
... other general anesthetics, propofol has relatively low affinities for protein targets, with the reported highest affinity propofol-protein interactions having low micromolar dissociation constants (Vedula ...
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Shedding Light On General Anesthesia: Uncovering The Molecular Mechanisms For Propofol And Volatile Anesthetics
... expensive, difficult to administer, and displayed many unwanted side effects 16 . A third gas, cyclopropane, also showed promise as an anesthetic if not for the coinciding extremely high explosive property 17,18 . ...
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MANAGING REFRACTORY DEPRESSION WITH KETAMINE AND NITROUS OXIDE
... of general anesthetics on neuronal activity could exert long-term therapeutic results in certain psychiatric conditions such as MD ...two general anesthetics from the past that ...
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37. Comparative study of isoflurane and ketamine anesthetics in Rabbits
... Administering anesthetics in rabbits is considered safe, when all safety measures are taken which includes careful check-up of the rabbit, the correct anesthetics and recommended dosage regimen and its ...
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Mechanism of Anesthetic Action: Oxygen Pathway Perturbation Hypothesis
... Overall, it seems that each theory has its merits and may be partially correct. The lipid theory may be correct on the notion that membrane perturbation is related to anesthesia but incorrect on the notion that membrane ...
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Natural Plant Compounds with Possible Interaction with Anesthetics
... Nowadays, the use of herbal medicine is very common, but the knowledge about the mechanism of action, metabolism of such preparations, and the clinical effects of many of the herbal preparations is still unknown. In many ...
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<p>The Role of Inhaled Anesthetics in Tumorigenesis and Tumor Immunity</p>
... whether general anesthetics, especially inhalational anesthetics, may induce growth, migration and invasion of cancer ...Inhaled anesthetics, often widely used for induction and maintenance of ...
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The Impact of Anesthetics Drugs on Memory and Memory Modulation under General
... General anesthesia (GA) is an induced, temporary state with unconsciousness, amnesia, analgesia and paralysis. While analgesia and muscle relaxation are respectively obtained with narcotic and ...
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A QSAR Study of the Activity of Some Fluorinated Anesthetics
... potent anesthetics widely used in medical applications are fluorinated anesthetics such as alkanols ...of anesthetics made it hard for early researchers to attribute the general ...
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Age-dependent postoperative cognitive impairment and Alzheimer-related neuropathology in mice
... of general anesthetics (under local anesthe- sia), induced brain Ab accumulation and cognitive impairment in aged WT mice and AD Tg mice, but not adult WT ...
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In vivo measurement of protein functional changes
... Conformational changes in proteins are fundamental to all biological functions. In protein science, the concept of protein flexibility is widely used to describe protein dynamics and thermodynamic properties that control ...
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Comparison of anesthetics in electroconvulsive therapy: an effective treatment with the use of propofol, etomidate, and thiopental
... retrospective study without randomization of patients to study groups, and thus it might have a selection bias. This is also a study without blinding, so it might have an observa- tional confirmation bias as well. In ...
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Anti inflammatory properties of anesthetic agents
... When administered over prolonged periods, short- and intermediate-acting barbiturates, which act as GABA re- ceptor agonists, may induce iatrogenic immunosuppres- sion. A higher incidence of infections has been described ...
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Efficacy and safety of 0.5% levobupivacaine versus 0.5% bupivacaine for peribulbar anesthesia
... Older age or the presence of a chronic medical condition may be a contraindica- tion for general anesthesia, except in particular situations such as an emergency involving multiple trauma or in pediatric or ...
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Kidney Function in Living Donors Undergoing Nephrectomy by Sevoflurane or Desflurane Anesthesia
... volatile anesthetics currently used in general anesthesia, a better agent should be needed in terms of preserving postoperative renal function in living kidney donors who have only single remaining ...
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The effects temperature and anesthetic agents on ciliary function in murine respiratory epithelia
... intravenous anesthetics. Volatile anesthetics, such as isoflurane (iso), have been shown to depress CBF and inhibit mucociliary clearance ...intravenous anesthetics, such as ketamine and fentanyl ...
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