genetic determinants
Genetic determinants of statin intolerance
... Genetic determinants of statin intolerance include both common SNPs and rare mutations. For instance, a study conducted primarily in a sample of patients with statin- induced myopathy ascertained through ...
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Genetic Determinants of Financial Risk Taking
... Genetic Determinants of Financial Risk Taking Kuhnen, Camelia M.. Northwestern University – Kellogg School of Management, Northwestern University.[r] ...
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Genetic determinants of mammographic density
... Catechol metabolites of estrogen (i.e. 2-OH and 4-OH estrogens) have been demonstrated to have cancer-pro- moting properties [25]. One route of catechol estrogen inactivation is by O-methylation, which is catalyzed by ...
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Genetic determinants of Nef mediated CD4 and HLA class I down regulation differences between HIV 1 subtypes B and C
... Genetic determinants of Nef mediated CD4 and HLA class I down regulation differences between HIV 1 subtypes B and C SHORT REPORT Open Access Genetic determinants of Nef mediated CD4 and HLA class I do[.] ...
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Genetic determinants of Sindbis virus neuroinvasiveness.
... After peripheral inoculation of mice, Sindbis virus replicates in a variety of tissues, leading to viremia. In some cases, the virus can enter the central nervous system (CNS) and cause lethal encephalitis. The outcome ...
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A murine model of genetic determinants of RSV disease
... Considerable evidence has suggested that genetic background is an important determinant of RSV disease severity, but the identity of susceptibility genes remains unclear. To determine the within-strain variation ...
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Overview of the genetic determinants of primary aldosteronism
... Abstract: Primary aldosteronism is the most common cause of secondary hypertension. The syndrome accounts for 10% of all cases of hypertension and is primarily caused by bilateral adrenal hyperplasia or ...
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The genetic determinants of lamotrigine dosing in epilepsy
... by genetic variation in these four SNPs ...summary, genetic variants in SLC22A1 appear to have a significant influence on LTG dose requirement but it is questionable whether this study has reliably ...
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Bacteria Getting into Shape: Genetic Determinants of E coli Morphology
... IMPORTANCE Genetic perturbations of cellular functions are a prevailing approach to understanding cell systems, which are increasingly being practiced in very high ...of genetic mutation on cell ...
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Genetic Determinants of Ethanol-Induced Liver Damage
... groups. Genetic dissection of this complex trait is further hampered because the genes involved can influence not only the probability of disease development but also the drinking behavior, thus changing the fre- ...
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STUDY OF THE GENETIC AND EXTRA GENETIC DETERMINANTS OF ALPHA KETOSTEROID PRODUCTION IN MAN
... Ossification SUM MARY The steroid patterns of normal adult, male, dichorionic, monozygotic triplets were examined in detail during control periods and during adrenocortical stimulation w[r] ...
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Neural and genetic determinants of creativity
... to genetic and environmental interactions (Blunt, ...the genetic causes of creativity may be diverse, many heterogeneous genes have been implicated in creativity such as those affecting DA, 5HT or GABA ...
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An Overview on the Genetic Determinants of Infertility
... FSHβ gene mutation has been shown to cause absent or incomplete breast development, low FSH and oestradiol, high LH and sterility in females [20]. Similarly, Xp11 gene deletions result in ovarian failure as well as ...
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Mendelian randomization and mediation analysis of leukocyte telomere length and risk of lung and head and neck cancers
... between genetic determinants of long telomeres and increased risk of lung, but not head and neck ...of genetic susceptibility in individuals with a lower burden of modifiable risk factors ...of ...
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Genetics of Skeletal Evolution in Unusually Large Mice from Gough Island
... the genetic basis of skeletal variation has been studied in laboratory strains, especially in the house mouse Mus musculus domesticus , the genetic determinants of skeletal evolution in natural ...
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Aspects of wool follicle morphology and cell proliferation in Romney sheep selected for high fleece production : a thesis presented in partial fulfilment of the requirements for the degree of Doctor of Philosophy in Veterinary Science at Massey University
... Genetic determinants of wool growth can be expected to be: - the total number of follicles - the number and size of cells in the proliferative zone of the follicle bulb - the proliferati[r] ...
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A point mutation in the env gene of a murine leukemia virus induces syncytium formation and neurologic disease.
... Previous studies using recombinant viruses constructed with the neuropathogenic TR1.3 and the nonneuropathogenic Friend MuLV, FB29 25, demonstrated that the genetic determinants responsi[r] ...
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Characterization of an Enterococcus gallinarum Isolate Carrying a Dual vanA and vanB Cassette
... Genetic characterization of vancomycin resistance. Isolate A6981 was positive for vanC1, vanA, and vanB genes by PCR. Considering that vanA and vanB clusters are commonly acquired through mobile, conjugative ...
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Tumor suppressor genes promote rhabdomyosarcoma progression in p53 heterozygous, HER-2/neu transgenic mice
... A further general question to which the BALB- p53Neu model could contribute is that of the anatomical specificity of carcinogenesis. In most human cancer syndromes only a very specific set of tissues and organs is ...
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Variance Components Models for Analysis of Big Family Data of Health Outcomes in the Lifelines Cohort Study
... of determinants on health outcome variables differs with and without accounting for family ...environmental determinants of healthy ...of determinants on health outcome variables does not differ with ...
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