Genetic Mechanisms and Development
Genetic mechanisms of knee osteoarthritis: a population based longitudinal study
... defect development in medial tibiofemoral and patellar com- partments and a greater decline in physical work capacity than controls during two years. Interestingly, these differences seemed largely to be mediated ...
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Genetic mechanisms of knee osteoarthritis: a population based longitudinal study
... defect development in medial tibiofemoral and patellar com- partments and a greater decline in physical work capacity than controls during two years. Interestingly, these differences seemed largely to be mediated ...
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Fronto-striatal plasticity processes in humans: glutamatergic and genetic mechanisms
... As mentioned in the previous section, human neuroscience evolves constantly. While we already gained valuable insights into the systems function of our brains and its aberrations in pathological conditions and ...
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Conserved genetic mechanisms for embryonic brain patterning
... brain development in two genetic model systems, Drosophila and ...the genetic mechanisms involved in embryonic brain development are conserved and indicative of a common evolutionary ...
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Genetic and Epigenetic Mechanisms of Tumorigenesis in Lynch and Lynch-like Syndrome
... cancer development can be inherited, which results in the lower age of ...to genetic factors and ranges from 0% (all variability is due to environmental factors) to 100% (all variability is due to ...
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Unraveling genetic mechanisms in autism spectrum disorders
... ATXN1 gene previously reported susceptibility gene for learning difficulties. In the whole genome screening of 223 ASD patients by array-CGH (paper III), clinically significant CNVs were identified in 18 individuals (8%) ...
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Shared Molecular Genetic Mechanisms Underlie Endometriosis and Migraine Comorbidity
... tumorigenesis, development and differentiation, as well as innate ...biological mechanisms including the roles of elevated levels of circulating prostaglandins [27], hormonal fluctuations [13], and impaired ...
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Phenotypes and genetic mechanisms of C. elegans enhanced RNAi
... facile genetic analysis. Extensive genetic analysis of the mechanisms, delivery, and regulation of RNAi in ...and development of RNAi in other nematodes, including parasitic nematodes where ...
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Developmental genetic mechanisms of evolutionary tooth loss in cypriniform fishes
... Pharyngeal tooth expression of zebrafish dlx2a and dlx2b is Fgf dependent (Jackman et al., 2004), whereas oral epithelial expression of mouse Fgf8, Shh and Pitx2 is not (Mandler and Neubüser, 2001). As dlx2a and dlx2b ...
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The Genetic Mechanisms Underlying Human Obesity
... This project was designed to investigate possible genetic associations between five candidate genes and severe obesity in both adult and child French Caucasians (n=2,822). Tag SNPs were chosen along with a ...
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Mechanisms of stomatal development: an evolutionary view
... Plant development has a significant postembryonic phase that is guided heavily by interactions between the plant and the outside ...the development, pattern and function of stomata, epidermal pores on the ...
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HIV associated lipodystrophy: Study of Molecular Mechanisms And Genetic Susceptibility
... its mechanisms because of its clinical importance, in longer term cardiovascular complications, as well as the reduction in the quality of life of HIV patients but its mechanism is still not clearly ...
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The eye contact effect: mechanisms and development
... Currently most of the accounts of the eye contact effect that have been given are either insufficiently detailed to generate testable predictions, or are specific to a particular experimental paradigm. Two general ...
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A molecular and genetic characterization of the mechanisms of histone mRNA metabolism in Drosophila
... histone mRNA deposited into the egg despite the histone mRNA being processed normally is that during the final stages of oogenesis there is a large final rapid burst of histone mRNA transcription that is not associated ...
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Mechanisms of tissue fusion during development
... Recent genetic studies provide important information on the molecular mechanisms that directly regulate fusion of the neural ...in genetic background and the specific mutation, yet all exhibit highly ...
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Mechanisms of Genetic Exchange Within the Chromosomal Inversions of Drosophila pseudoobscura
... The conversion tract data show that the sources for observed gene conversion tracts tend to be the more ancestral arrangements. Of 19 observed conversion tracts for genes in inverted regions, 11 used either the Tree Line ...
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The channelopathies: novel insights into molecular and genetic mechanisms of human disease
... But the link to human disease has come from clinical investigations of congenital disorders and the discoveries that defects in genes coding for ion channels or ion channel regulatory su[r] ...
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Molecules and mechanisms of dendrite development in Drosophila
... Dscam control of dendritic self-avoidance in Drosophila In numerous cell types, dendritic branches that originate from the same neuron (sister branches) will not cross or fasciculate, and this self-avoidance (see ...
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Mechanisms and treatment of ischaemic stroke: insights from genetic associations
... high genetic risk. Furthermore, patients with a low genetic risk might take less care to minimize general risk factors, thereby increasing their risk of ...after genetic profil- ing for the ...
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Genetic Polymorphism in Wine Yeasts: Mechanisms and Methods for Its Detection
... In some cases, polymorphisms have been demonstrated as being involved in generating phenotypic variation in yeast properties of biotechnological interest. By way of example, Marullo et al. (2007) studied the ...
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