Genome-Wide Association Study (GWAS)
Susceptible gene of stasis stagnation constitution from genome wide association study related to cardiovascular disturbance and possible regulated traditional Chinese medicine
... present study, a genome-wide association study was conducted to identify susceptible loci related to the YZ constitution in patients with type 2 ...to study the protein-ligand ...
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A Genome-Wide Association Study (GWAS) for Bronchopulmonary Dysplasia
... discovery GWAS was completed on 1726 very low birth weight infants (gestational age = 25 0 – 29 6/7 weeks) who had a minimum of 3 days of intermittent positive pressure ventilation and were in the hospital at 36 ...
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Genome-wide association study identifies five new schizophrenia loci.pdf
... of association in eight replication samples are represented by + if the associations are in the same direction, − if they are in opposite directions and a blank space if the data are not ...
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A functional variant rs12904 in the miR-200c binding site was associated with a decreased risk of ischemic stroke
... 2009, genome-wide association study (GWAS) identi- fied that single nucleotide polymorphisms (SNPs) on chromosome 12p13 ...replication study performed in a Swedish popula- tion, ...
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<em>HSD17B12</em> gene rs11037575 C>T polymorphism confers neuroblastoma susceptibility in a Southern Chinese population
... previous genome-wide association study (GWAS) identified four genetic polymorphisms (rs1027702 near DUSP12, rs10055201 in IL31RA, rs2619046 in DDX4, and rs11037575 in HSD17B12 gene) ...
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Discovery of Candidate Genes for Muscle Traits Based on GWAS Supported by eQTL-analysis
... Linkage, association, and expression analyses independently contributed to the identification of trait-associated molecular pathways and ...a genome-wide association study (GWAS) ...
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Lack of association between the CHL1 gene and adolescent idiopathic scoliosis susceptibility in Han Chinese: a case control study
... previous genome-wide association study (GWAS) suggested a strong association between the single nucleotide polymorphism (SNP) rs10510181 in the proximity of the gene encoding a ...
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Research Highlights
... published genome-wide association study (GWAS) dataset, they demonstrated that neuronal function genes within their identified network modules were enriched for variants associated with ...
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Computational genetics analysis of grey matter density in Alzheimer’s disease
... this study comes from the Alzheimer ’ s Disease Neuroimaging Initiative (ADNI), which began on October 1, 2004 ...multisite study is to define the rate of progress of mild cognitive impairment and ...
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Original Article Genetic variant in ZFHX3 Geneon 16q22 associated with risk of stroke in Chinese Han population
... A genome-wide association study (GWAS) in patients of European population has identified that risk variants in ZFHX3 on 16q22 was related with stroke and atrial fibrilla- tion (AF) ...
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Epidemiology, genetics, and subtyping of preserved ratio impaired spirometry (PRISm) in COPDGene
... a genome-wide association study (GWAS) of PRISm status relative to control subjects; results for the analysis in fixed threshold-defined cohorts are illustrated in Additional file 1: ...
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Genetic contributions to variation in general cognitive function: a meta-analysis of genome-wide association studies in the CHARGE consortium (N=53 949)
... this study (SNP and gene-based) were compared with those of previously published large GWAS of educational attainment 35 and general cognitive function in ...current study (overlaps are: educational ...
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Combining Genome Wide Association Studies and Differential Gene Expression Data Analyses Identifies Candidate Genes Affecting Mastitis Caused by Two Different Pathogens in the Dairy Cow
... present study two published datasets were searched for common differentially expressed genes (DEGs) with similar changes in expression in mammary tissue following intra-mammary challenge with either ...published ...
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Evaluation of the association of C5 with neovascular age-related macular degeneration and polypoidal choroidal vasculopathy
... analysis, genome-wide association studies (GWAS), and exome- wide association studies (EWAS), have identified single- nucleotide polymorphisms (SNPs) in over 30 genes that are ...
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Genome wide association studies: a primer
... The most important issue in a case-control study is how to define cases and controls, and this is particu- larly so in psychiatric genetics. This is more difficult to define and measure than for most non-psychiatric ...
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Genome wide protein QTL mapping identifies human plasma kallikrein as a post translational regulator of serum uPAR levels
... a genome-wide association study of serum scuPAR levels identified a human plasma kallikrein gene (KLKB1) promoter polymor- phism (rs4253238) associated with serum scuPAR levels in a ...
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Pilot GWAS of caries in African-Americans shows genetic heterogeneity
... of GWAS tagSNPs show effect heterogeneity by ances- try ...[12]. Genome-wide association studies (GWAS) of dental caries in African American samples have not been performed, and ...
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A meta-analysis of genome-wide association studies of growth differentiation Factor-15 concentration in blood
... current study. GWAS and meta-analyses were carried out using two ...the GWAS, Framingham used a linear mixed model to accommodate the relatedness among the participants as implemented in the R ...
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A polygenic burden of rare disruptive mutations in schizophrenia.
... 2011), association testing across all genes is likely to be under-powered at current sample ...large-scale genome-wide screens, including GWAS, CNV and de novo SNV studies, testing for ...
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A Review of Prostate Cancer Genome-Wide Association Studies (GWAS).
... large GWAS backbone (260,000 SNPs) on the OncoArray allowed investigators to utilise LD to increase the power of variant ...this study also allowed several sub-analyses of clinical and demographic factors ...
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