Genome-wide screen
A Genome Wide Screen of Deletion Mutants in the Filamentous Saccharomyces cerevisiae Background Identifies Ergosterol as a Direct Trigger of Macrophage Pyroptosis
... a genome-wide screen of nonessential ⌺ 1278b Saccharomyces cerevisiae genes to identify genes re- quired for yeast-triggered macrophage ...this screen was enriched for those with functions in ...
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Genome-Wide Screen for Inner Nuclear Membrane Protein Targeting in Saccharomyces cerevisiae
... first genome-wide screen to identify proteins functioning in INM ...obtain genome-wide perspectives of mechanisms necessary to achieve appropriate subcellular and/or suborganellar ...
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Genome-wide screen for modifiers of Na+/K+ATPase alleles identifies critical genetic loci
... the genome (95-98%), one can identify critical modifier loci anywhere in the gen- ...a screen using ATPalpha DTS1 , ATPalpha CJ5 and ATPalpha CJ10 , identified 64 critical modifier intervals, and ...
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Genome-Wide Screen Reveals Valosin-Containing Protein Requirement for Coronavirus Exit from Endosomes
... The function of VCP in endosomal maturation is still unclear. A recent report proposes a function for VCP in membrane fusion and early endosome maturation through the segregation of EEA1 polymers (45). Another report ...
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A Genome-Wide Screen Reveals that the Vibrio cholerae Phosphoenolpyruvate Phosphotransferase System Modulates Virulence Gene Expression
... Here, we carried out a transposon insertion site (TIS) sequenc- ing-based screen to identify new regulators of TcpA expression. In addition to most known regulators, our screen yielded compo- nents of the ...
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Genome-Wide Screen for Genes With Effects on Distinct Iron Uptake Activities in Saccharomyces cerevisiae
... present screen, we selected strains grown on sidero- phore-free medium that showed high-FOB uptake, thus excluding putative mutants that would show unre- pressed siderophore uptake because of a defect in side- ...
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A genome wide screen in EpiSCs identifies Nr5a nuclear receptors as potent inducers of ground state pluripotency
... Nr5a receptors are potent EpiSC reprogramming factors but are not ES cell self-renewal factors By utilising the MSCV enhancer/promoter, which drives moderate transcription and is subject to silencing, the screen ...
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A Genome Wide Screen Identifies Genes in Rhizosphere Associated Pseudomonas Required to Evade Plant Defenses
... Tn-Seq screen to those identified in several recent screens for genes that affect the fitness or growth promotion ability of rhizosphere-associated Pseudomonas ...
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Genome-wide screen for modifiers of Parkinson's disease genes in Drosophila
... our screen using deficiencies greatly increases the coverage of genomic regions, there are several lim- ...our screen if both enhancers and sup- pressors are located within the same ...our screen may ...
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A genome-wide siRNA screen identifies a druggable host pathway essential for the Ebola virus life cycle
... primary screen as part of our secondary assay, and specifically on host factors required for genome replication and transcription, fur- ther in-depth analysis of the data might reveal additional pro- and ...
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Genome Wide siRNA Screen Identifies Complementary Signaling Pathways Involved in Listeria Infection and Reveals Different Actin Nucleation Mechanisms during Listeria Cell Invasion and Actin Comet Tail Formation
... a genome-wide screen performed in duplicate and ranked accord- ing to the normalized infection level, microscopically quantified based on InlC secretion: a negative Z score indicates that cell in- ...
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A Genome-Wide Small Interfering RNA Screen Identifies Host Factors Required for Vesicular Stomatitis Virus Infection
... a genome-wide siRNA ...secondary screen of 450 host genes isolated from the genome-wide siRNA screen ...the genome-wide screen and the demonstration that ...
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Common variation near ROBO2 is associated with expressive vocabulary in infancy
... a genome-wide screen and follow-up study of expressive vocabulary in toddlers of European descent from up to four studies of the EArly Genetics and Lifecourse Epidemiology consortium, analysing an ...
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Genome Wide Transposon Screen of a Pseudomonas syringae mexB Mutant Reveals the Substrates of Efflux Transporters
... This genome-wide screen performed in a hypersusceptible mutant strain revealed numerous transporters that would otherwise be dispensable under these ...
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Common variation near ROBO2 is associated with expressive vocabulary in infancy
... Genome-wide screen of rank-transformed expressive vocabulary scores between 15–18 months of age in children of European ancestry. Discovery analysis was conducted in ALSPAC (Abbreviated Infant CDI 13 ...
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A Genome Wide Knockout Screen in Human Macrophages Identified Host Factors Modulating Salmonella Infection
... Another candidate, NHLRC2 (NHL-repeat-containing protein 2), was one of the top 3 mutants identified in our genome-wide screen. A homozygous mutant clone, NHLRC2_E1_D5, showed strong resistance to ...
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A Genome-Wide Small Interfering RNA Screen Identifies Host Factors Required for Vesicular Stomatitis Virus Infection
... a genome-wide siRNA ...secondary screen of 450 host genes isolated from the genome-wide siRNA screen ...the genome-wide screen and the demonstration that ...
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Genetic correlation and genome-wide association study (GWAS) of the length of productive life, days open, and 305-days milk yield in crossbred Holstein dairy cattle.
... (2003) reported the effect of QTL region on the length of productive life and the effect of the SIGLEC12 gene on BTA18 on the longevity of the German Holstein population. However, many[r] ...
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Genome-Wide Analysis of a Radiation-Induced Lesion Mimic Mutant in Rice
... SNPs and indels are present in different individuals of the same plant and affect their gene expression and phenotypes in the genome (Huang et al. 2012). We identified 3,856 non-synonymous and 90 stopgain SNPs. ...
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Genome-wide association analysis of body conformation traits in Mexican Holstein cattle using a mix of sampled and imputed SNP genotypes.
... a genome-wide association analysis for a set of sampled and imputed SNPs with 16 conformation traits in a population of Mexican Holstein cows, revealed eight significant SNPs: one associated with the Body ...
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