Genomic Medicine
What is genomic medicine?
... with genomic medicine can create communication barriers between scientists and nonscientists, as the general public and even general health care practitioners might not sufficiently understand ...
7
Newborn Sequencing in Genomic Medicine and Public Health
... rapid genomic sequencing appear feasible, interpretation of each asymptomatic person’s variant profile will remain labor intensive for the foreseeable future, and clinically useful prediction of future disease may ...
15
Coverage of genomic medicine: information gap between lay public and scientists
... Project, genomic medicine, personalized medicine, made-to-order medicine, and tailor-made ...to genomic medicine and other relevant ...
8
Success stories in genomic medicine from resource-limited countries
... of genomic medicine, that is well established in South Africa [31], in some Northern African countries [32, 33], and recently initiated in Central Africa ...Malaria Genomic Epidemiology Network ...
7
Whole-genome haplotyping approaches and genomic medicine
... DNA diagnostics and prognostics that have clinical ap- plications in oncology are expanding rapidly. For example, particular haplotypes of GNMT (encoding glycine N- methyltransferase) differently predispose individuals ...
16
Whole genome sequencing of one complex pedigree illustrates challenges with genomic medicine
... Despite much success using NGS-based techniques to identify mutations, there are still practical issues for the analytic validity for exome- or genome-wide NGS-based techiques, particularly in clinical settings [21, 22]. ...
16
Known unknowns: building an ethics of uncertainty into genomic medicine
... in genomic medicine? Our answer is that while we do not wish to underplay the im- pact that uncertainty can have in genomic testing, a pre- sumption that uncertainty is necessarily problematic or ...
8
The IGNITE network: a model for genomic medicine implementation and research
... of genomic medicine, or the use of an individual patient’ s genomic information (as reflected by family history, genotyping, sequencing or other DNA- based technology) into clinical decision making, ...
13
Identifying disease mutations in genomic medicine settings: current challenges and how to accelerate progress
... high-throughput sequencing in genomic medicine have been the identification of the causes of many clinically characterized Mendelian disorders (that is, single gene disorders). Furthermore, exome sequencing ...
16
Looking back at genomic medicine in 2011
... of genomic medicine continues to be intrinsically linked to improvements in the underlying technology, and two obvious examples are sequencing and mass spec ...translating genomic medicine to ...
5
The second international genomic medicine conference (2nd IGMC, 2013): brief report and outcome
... in Genomic Medicine Research (CEGMR, at King Abdulaziz University (KAU) [1], is a leading centre in the field of medical genomics research in the Western province of the Kingdom of Saudi ...International ...
5
Harmonizing Outcomes for Genomic Medicine: Comparison of eMERGE Outcomes to ClinGen Outcome/Intervention Pairs
... Genomic medicine is moving from research to the ...of genomic medicine interventions on health ...of genomic results to participants for several genetic ...for genomic ...
17
From genomic medicine to precision medicine: highlights of 2015
... Precision medicine is now taking off as an important topic in the public health sphere and in education, and no discussion of 2015 would be complete without a mention of the huge advances in gene editing ...
5
Primary care providers’ experiences with and perceptions of personalized genomic medicine
... personalized medicine, available tests, and triggers for appropriate referral for genetic coun- seling and ...personalized medicine and yet, based on responses pro- vided, others were not cognizant of their ...
10
Genomic Epidemiology of Congestive Heart Disease, Pharmacogenomics and the Relevant Health Education Implications in the Age of Genomic Medicine
... Today, an improvement in the technology for biochemical analysis of patients’ specimen has enhanced the knowledge about the incipient signs of diseases, diagnosis, treatment and prevention of these diseases. The recently ...
14
Genomic Medicine: The Human Genome Project from a Healthcare Provider's Perspective
... So first, we talked a little bit about the promises, and then I want to outline some genetic myths, things that we all carry around with us that we think are true when, in fact, may [r] ...
7
A Centralized Approach for Practicing Genomic Medicine
... who did not receive it because of insurance barriers before the establishment of the RIMGC are not available across the enterprise. Because direct patient care accounted for 28% of staff efforts while the generation of ...
12
Immunoinformatics and epitope prediction in the age of genomic medicine
... With the availability of large-scale NGS data, a num- ber of novel applications are now within reach. The full genomic sequence of pathogens together with informa- tion on genomic variability (e.g., from ...
12
Clinical spectrum of POLR3-related leukodystrophy caused by biallelic POLR1C pathogenic variants
... of Medicine, University of Szeged, Szeged, Hungary; Child Health and Human Development Program ...of Medicine, The Chinese University of Hong Kong, Hong Kong, China; Developmental Neurology Department ...
14
FINGER PHOTOPLETHYSMOGRAPH AS A MONITORING DEVICE FOR LIPID PROFILE IN MEN WITH CARDIOVASCULAR RISK
... This paper aims to develop a modular schema database for gene-associated diseases incidence in Indonesia, which is called as Genomic Medicine Research Group Database (GMRGDB). A modular architecture is ...
10