Germ cell tumour.
Retroperitoneal teratoma with somatic malignant transformation: A papillary renal cell carcinoma in a testicular germ cell tumour metastasis following platinum-based chemotherapy
... mixed germ cell tumour (Stage III, poor ...a germ cell tumour metastasis consisting mainly of mature ...renal cell carcinoma was ...
5
Bilateral Mixed Germ Cell Tumour in an Adolescent Girl with Premature Ovarian Failure
... Germ cell tumours (GCTs) of the ovary are rare, comprising approximately 20% of all ovarian tu- mors with the malignant variant accounting for less than 5% of all ovarian ...mixed germ cell ...
5
Large-scale Sequencing of Testicular Germ Cell Tumour (TGCT) Cases Excludes Major TGCT Predisposition Gene.
... Testicular Germ Cell Tumour (TGCT), the most common cancer in young men, has a significant heritable basis, which has long raised the question of existence of underlying major high-penetrance ...
13
Multi-stage genome-wide association study identifies new susceptibility locus for testicular germ cell tumour on chromosome 3q25
... Testicular germ cell tumour (TGCT) is the most common cancer in men aged 15-45 years, with over 18,000 new cases diagnosed annually in Europe 1,2 ...
24
Accelerated BEP : a phase I trial of dose dense BEP for intermediate and poor prognosis metastatic germ cell tumour
... Ethical approval was granted by the UK’s Eastern Multi-Centre Research Ethics Committee (EudraCT number: 2004 – 000847 – 79, ISRCTN18505589) and all patients gave written informed consent. Patients were eligible for this ...
8
IGF1R signalling in testicular germ cell tumour cells impacts on cell survival and acquired cisplatin resistance.
... Testicular germ cell tumours (TGCTs) are the most frequent malignancy and cause of death from solid tumours in the 20- to 40-year age ...TGCT cell lines representing the nonseminomatous ...in ...
12
Disease characteristics and survival outcomes of extragonadal primary germ cell tumour in two Canadian tertiary cancer centres
... on tumour markers or clinical ...in tumour markers or radiologic progression after the first-line cura- tive therapy was finished; post-chemotherapy resection of residual tumour was considered to be ...
6
Identification of four new susceptibility loci for testicular germ cell tumour
... Pathway analysis. We performed gene set enrichment analysis to determine whether any of the genes mapping to our four newly identified loci reside in pathways already enriched with TGCT SNPs. Using the i-GSEA4GWAS ...
8
Conclusion Functional ovarian cysts were the most commonly encountered ovarian lesions in our study
... Table 3 shows classification of ovarian tumours according to the WHO classification of these tumours and Table 4 shows the age distribution. The most common tumour among them was germ cell ...
5
Meta-analysis of cancer triploidy: Rearrangements of genome complements in male human tumours are characterised by XXY karyotypes
... The tumour Nomenclature used was based on the International Classification of Diseases for Oncology (ICD-O), the Systematized Nomenclature of Medicine (SNOMED), and the WHO Classification of Tumours of Soft Tissue ...
16
Factor V Leiden mutation triggering four major complications to standard dose cisplatin-chemotherapy for testicular seminoma: a case report
... Background: Major life-threatening complications secondary to cisplatin-based chemotherapy are rare in patients with testicular germ cell tumour (GCT). The incidence of complications increases with ...
5
Imaging of testicular germ cell tumours.
... raised tumour marker levels but no definite disease on conventional ...seminomatous germ cell tumour has been investigated by the Medical Research Council (MRC) in the UK in the TE22 ...
11
Nodal/Cripto signaling in fetal male germ cell development: implications for testicular germ cell tumors
... Nodal, a member of the TGF b family, signals by binding to Activin receptors (serine/threonine kinase receptors, predomi- nantly Alk4 (Acvr1b) and ActRIIA/B (Acvr2a/b)) in the presence of the obligate co-receptor, Cripto ...
10
Nodal induces sequential restriction of germ cell factors during primordial germ cell specification
... 1. Germ cell factors are restricted dorsally and on the left during ...Primordial germ cells can be specified by either inherited mechanisms or inductive ...of germ cell factors in the ...
9
The genetic basis of Lynch syndrome and its implications for clinical practice and risk management
... Germ line mutations of mismatch repair genes in hereditary nonpolyposis colorectal cancer patients with small bowel cancer: International Society for Gastrointestinal Hereditary Tumour[r] ...
12
In vitro anticancer activity of wheat germ extract on human breast cancer cell line (MCF-7) and human immortalized myelogenous leukemia cell line (K562)
... leukemia cell line was obtained from (Faculty of Medicine, The University of Jordan) and was cultured in RPMI while the MCF-7 breast cancer cells were obtained from American Type culture collections (ATCC) and ...
5
INTRA-OPERATIVE FROZEN SECTION CONSULTATION: CONCEPTS, APPLICATIONS AND LIMITATIONS
... The pathologist should attend the FS fully prepared which include reading the literature about the suspected tumour and the possible histological variants and grading. With the relevant clinical information, the ...
9
Developmental fates of the mouse germ cell line
... female germ cells from entering meiosis ...male germ cells was not induced in cultured fetal gonads, as it was in embryos, but conditioned media obtained from cultures of ovaries or testes, or follicular ...
6
Pretreatment Diagnosis of Suprasellar Papillary Craniopharyngioma and Germ Cell Tumors of Adult Patients
... This retrospective study was reviewed by an institutional review board. Between 2003 and 2013, 58 patients with craniopharyngi- oma and 17 patients with germ cell tumors who were older than 16 years of age ...
10
FSH initiated differentiation of newt spermatogonia to primary spermatocytes in germ somatic cell reaggregates cultured within a collagen matrix
... stimulates germ cell proliferation via Sertoli cells (Maekawa et ...of germ cells differentiating into primary spermatocytes were proportional to the percentage of somatic cells in the culture, ...
6