Global Ischemia
Human Myocardium Releases Heat Shock Protein 27 (HSP27) after Global Ischemia: The Proinflammatory Effect of Extracellular HSP27 through Toll-like Receptor (TLR)-2 and TLR4
... Because IL-6 secretion is sensitive to a very low level of endotoxin (36), we de- termined whether the trace amount of endotoxin in the recombinant HSP25 preparation has a proinflammatory effect on mouse hearts. We ...
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Original Article Ki20227 influences the morphology of microglia and neurons through inhibition of CSF1R during global ischemia
... during global ischemia led to a significant deficit in microglial density in the CNS in mice, and CSF1R-inhibition led to a significant reduction in the neuronal density of ...during global ...
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Efficacy of Radix Ginseng Against Reperfusion After Regional or Global Ischemia in the Dog: An Assessment on Myocardial Ultrastructure
... Efficacy of Radix Ginseng Against Reperfusion After Regional or Global Ischemia in the Dog An Assessment on Myocardial Ultrastructure ORIGINAL ARTICLE Efficacy of Radix Ginseng Against Reperfusion Aft[.] ...
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Neurogenic coronary vasoconstrictor effects of digitalis during acute global ischemia in dogs
... ischemia. The present study evaluates the effects of i.v. acetylstrophanthidin and digoxin on coronary vascular resistance during acute global ischemia in 29 dogs anesthetized with chloralose and ...
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Time course of oxidative damage in different brain regions following transient cerebral ischemia in gerbils
... forebrain ischemia in the gerbil hippocampus (Floyd and Carney, 1991; Haba et ...in global cerebral ischemia in our experimental ...near-complete global ischemia (Hall et ...transient ...
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Protection against myocardial dysfunction after a brief ischemic period in transgenic mice expressing inducible heat shock protein 70
... of global ischemia in an isolated Langendorff ...myocardial ischemia created by occlusion of the left descending coronary artery, followed by 60 min of ...of global ischemia and 90 min ...
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Effect of L Deprenyl on the Putrescine Level and Neuronal Damage after Transient Global Cerebral Ischemia in Gerbils
... lular compartment bind to the NMDA receptor of cells located in close vicinity and thus render neurons vulnerable to subtoxic levels of excitotoxins. Several researchers examined the changes in brain polyamine levels ...
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Structure activity relationship of bioactive compounds from medicinal plants.
... region. Global cerebral ischemia entails diminution in cerebral blood flow over the entire brain, encountered clinically as sequelae during extracorporeal circulation following cardiac arrest from ...
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Mild hypothermia alone or in combination with anesthetic post conditioning reduces expression of inflammatory cytokines in the cerebral cortex of pigs after cardiopulmonary resuscitation
... cerebral ischemia/ reperfusion, there appears to be a reasonable therapeutic time window using mild hypothermia to favourably affect the inflammatory pathway ...any ischemia-induced damaging ...mental ...
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Model of Global Permanent Ischemia in Conditions of Normothermia and Hypothermia
... of global ischemia at the temperature of 37, 34 and ...the ischemia, a progressive reduction of the energetic metabolites (Figure 1; Tables 1- 5) can be ...
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The Role of Zinc in Cerebral Ischemia
... IN ISCHEMIA Tonder and colleagues (9) conducted the first study providing indirect evi- dence for the toxic translocation of zinc from presynaptic neurons into selective postsynaptic neurons during the experi- ...
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The choroid plexus as a site of damage in hemorrhagic and ischemic stroke and its role in responding to injury
... Because of its rich collateral circulation, focal cerebral ischemia probably rarely causes CP infarction. However, there is evidence suggesting that the CP is selectively vulnerable to ischemia. Further ...
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Comparison of Acute Alterations in Left Ventricular Relaxation and Diastolic Chamber Stiffness Induced by Hypoxia and Ischemia: ROLE OF MYOCARDIAL OXYGEN SUPPLY DEMAND IMBALANCE
... of ischemia on left ventricular chamber stiffness, we compared the effects of hypoxia at constant coronary perfusion with those of global ischemia on left ventricular diastolic chamber stiffness ...
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Protection of Hippocampal CA1 Neurons Against Ischemia/Reperfusion Injury by Exercise Preconditioning via Modulation of Bax/ Bcl-2 Ratio and Prevention of Caspase-3 Activation
... forebrain ischemia (Ouyang, Voloboueva, Xu, & Giffard, ...transient global ischemia for 15 min damages the vulnerable cells, particularly in the CA1 area of the hip- pocampus (Olsson, Wieloch, ...
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Age- and Gender-Related Differences in Ischemia/Reperfusion Injury and Cardioprotection: Effects of Diazoxide
... Mature male and female (A) left ventricular peak developed pressure (LVPDP); (B) left ventricular end-diastolic pressure (LVEDP) during equilibrium, global ischemia and reperfusion; and (C) infarct size (% ...
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The highly selective cyclooxygenase-2 inhibitor DFU is neuroprotective when given several hours after transient cerebral ischemia in gerbils
... before ischemia and again at 6, 12, 24, 48 and 72 h of reperfusion ...of ischemia, followed by additional single oral doses at 24, 48 and 72 ...after global ischemia ...
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Sphingosine-1-phosphate: distribution, metabolism and role in the regulation of cellular functions
... in ischemia- reperfusion events: S1P (1 and 10 mM) decreased infarct size and creatine kinase release while S1P or S1P(1)R-selective agonist SEW2871 was able to improve left ventricular developed ...[62]. ...
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Meta-analysis of targeted temperature management in animal models of cardiac arrest
... after ischemia, although this too showed efficacy across all outcomes ...of ischemia, and no clear difference of efficacy was seen between shorter and longer durations of ...
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Curcumin Effects on Memory Impairment and Restoration of Irregular Neuronal Distribution in the Hippocampal CA1 Region After Global Cerebral Ischemia in Male Rats
... ately or up to 7 days after the induction of brain isch- emia. Thus, there is no study on the long-term effects of treatment with curcumin and its time course effects on neurological and memory impairments following ...
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ASSESMENT OF THE ANTI INFLAMMATORY EFFECT OF CINEOL ON CEREBRAL ISCHEMIA REPERFUSION I/R INJURY
... Subsequent to seven days of adaptation, the rats had been divided randomly into four equal groups (each of 6). The 1 st Group was sham group: The rats had been exposed to the similar clinical processes like other groups ...
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