Glomerular mesangial cells (MCs)
Endothelin 1 stimulates contraction of rat glomerular mesangial cells and potentiates beta adrenergic mediated cyclic adenosine monophosphate accumulation
... in glomerular mesangial cells by activating the phosphoinositide ...stimulates mesangial cell contraction and regulates the synthesis of PGE2 and cAMP, which dampen vasoconstrictor-induced ...
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Low density lipoprotein enhances the cellular action of arginine vasopressin in rat glomerular mesangial cells in culture
... rat glomerular mesangial cells in ...When cells were preincubated for 24 h with 10 microgram/ml LDL, the 1 x 10(-7) M AVP- mobilized [Ca2+]i was 874 nM, a value significantly greater than that ...
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Original Article Mitofusin 2 expression in IgA1 induced rat glomerular mesangial cells and IgA nephrology animal model
... rat glomerular mesangial cells, while overexpressed Mfn2 could alleviate glomerular mesangial cell (GMC) proliferation and increase apoptosis, and that Mfn2 may exert its activi- ties ...
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Prostaglandin synthesis by rat glomerular mesangial cells in culture Effects of angiotensin II and arginine vasopressin
... the glomerular filtration rate and ultrafiltration ...cause mesangial cell ...rat glomerular mesangial ...passage. Mesangial cell morphology was confirmed by electron microscopy. ...
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Regulation of extracellular matrix by mechanical stress in rat glomerular mesangial cells
... in glomerular mesangial cells, re- peated cycles of stretching and relaxation lead to matrix ac- cumulation by stimulating production of extracellular ma- trix and decreasing activity of degradative ...
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Serial analysis of genes expressed in normal human glomerular mesangial cells
... Mesangial cells contain many of the same contractile proteins as smooth muscle cells but some isoforms of these contractile proteins are specific for SMC or MC (review ed in (Stockand and Sansom, ...
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Effects of Dangguibuxue decoction on rat glomerular mesangial cells cultured under high glucose conditions
... These results indicate that the inhibitory effect of DBD on proliferation of GMCs is dose- and time-dependent. Gao et al. reported that DBD extract reversed high glucose-induced inhibition of endothelial cell migration ...
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Cell cycle dependent interleukin 1 gene expression by cultured glomerular mesangial cells
... glomerulonephritis. To define the regulation of IL-1 synthesis by human MC, Northern blot analyses were performed using specific probes for monocytic IL-1 alpha and beta mRNA. Proliferating MC expressed mRNA for both ...
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Rat glomerular mesangial cells synthesize basic fibroblast growth factor Release, upregulated synthesis, and mitogenicity in mesangial proliferative glomerulonephritis
... various glomerular diseases in ...potent mesangial cell mitogen in ...rat mesangial cell (RMC) proliferation, we examined whether RMC synthesize bFGF in vitro and whether bFGF is involved in ...
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Transforming growth factor beta Murine glomerular receptors and responses of isolated glomerular cells
... resident glomerular cells and the accumulation of mesangial matrix are histologic abnormalities which are observed in the course of many progressive glomerular ...mouse glomerular ...
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IgG4-related kidney disease (IgG4-RKD) with membranous nephropathy as its initial manifestation: report of one case and literature review
... the mesangial area and capillary wall (immunofluorescence ...of glomerular mesangial cells and interstitial cells, moderate aggravation of focal segmental lesions, diffuse thickening of ...
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Contraction of Cultured Rat Glomerular Cells of Apparent Mesangial Origin after Stimulation with Angiotensin II and Arginine Vasopressin
... of glomerular mesangial cells were undertaken using homogeneous cultures of rat glomerular cells of apparent mesangial origin ...MS cells were treated with arginine ...
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Endothelium dependent vascular responses Mediators and mechanisms
... Simultaneously cocultured bovine glomerular mesangial cells, analogous to contractile VSM cells in larger vessels, respond by liberating cGMP, the latter effect blocked by methylene blue[r] ...
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Creation of an In vivo cytosensor using engineered mesangial cells Automatic sensing of glomerular inflammation controls transgene activity
... of glomerular mesangial cells has shed light on a-smooth muscle actin as a marker of mesangial cell activation ...muscle cells and pericytes, this actin isotype is absent in normal ...
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Effects of Carpio Decoction on the Structure of Kidney in Rats with Adriamycin Induced Nephrosis
... Renal glomerular capillaries congestive of group M rats were ...expansion. Glomerular mesangial cells and the basement mem- brane were diffuse hyperplasia, inflammatory cell ...infiltration. ...
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Wnt signaling regulates smooth muscle precursor development in the mouse lung via a tenascin C/PDGFR pathway
... in glomerular mesangial cells (13), raising the possibility that the regulation of Pdgfrα and Pdgfrβ expression by Wnt7b and β-catenin signaling during lung development shown in Figure 2 may be ...
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Naringin ameliorates the high glucose induced rat mesangial cell inflammatory reaction by modulating the NLRP3 Inflammasome
... rat glomerular mesangial cells, we used MCC950 to treat high-glucose ...in glomerular mesangial cells under high glucose conditions is at least partially derived from the as- ...
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Physiologic regulation of atrial natriuretic peptide receptors in rat renal glomeruli
... the glomerular ANP receptor with high affinity stimulated cGMP accumulation, whereas the (13-28) ANP fragment, which failed to bind to the receptor, was devoid of functional ...cultured glomerular ...
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Mesangial cells from patients with IgA nephropathy have increased susceptibility to galactose-deficient IgA1
... incubation, MCs were seen at the edges of the glomeruli that at- tached to the plate and were subcloned to new cell cul- ture plates without attachment ...human mesangial cells from renal biopsies is ...
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Hypercholesterolemia promotes early renal dysfunction in apolipoprotein E-deficient mice
... in glomerular tuft area were found, in agreement with no differences in glomerular volume in ApoE mice [18], renal histology analysis showed a marked mesangial expansion in young ApoE mouse, which ...
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