Glucagon Secretion
Influence of Basal Insulin and Glucagon Secretion on Potassium and Sodium Metabolism: STUDIES WITH SOMATOSTATIN IN NORMAL DOGS AND IN NORMAL AND DIABETIC HUMAN BEINGS
... and glucagon secretion in potassium and sodium homeostasis, somatostatin, a potent inhibitor of insulin and glucagon secretion, was infused for 5 h into healthy human subjects, maturity-onset ...
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Role of Calcium in Glucagon Secretion
... on glucagon and insulin release from the perfused rat pancreas were studied in the ab- sence or presence of arginine ...of glucagon release, whereas ouabain en- hanced glucagon secretion ...of ...
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Arginine stimulated acute phase of insulin and glucagon secretion in diabetic subjects
... of glucagon secretion, in response to arginine pulses at four different doses (submaximal to maximal alpha-cell stimulating), was indistinguishable in terms of timing, peak levels attained, and total ...
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The role of aminogenic glucagon secretion in blood glucose homeostasis
... exogenous glucagon/min was infused via the mesenteric vein with the amino acids, the fall in glucose was reduced to an average of 5 mg/100 ...endogenous glucagon secretion, plasma glucose did not ...
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The effect of experimental insulin deficiency on glucagon secretion
... of glucagon secretion, and that in diabetes an intracellular deficiency of glucose secondary to insulin lack might be responsible for the ...upon glucagon secretion of blockade of glucose ...
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Adrenergic Modulation of Pancreatic Glucagon Secretion in Man
... affect glucagon secretion in man and demonstrate that the pancreatic alpha cell possesses both alpha and beta adrenergic ...basal glucagon secretion, while alpha adrenergic stimulation ...
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In vivo inhibition of glucagon secretion by paracrine beta cell activity in man
... increased glucagon responses to arginine: 573 +/- 75 (basal), 829 +/- 114 (rate 1), and 994 +/- 136 ng/liter per 10 min (rate 2) and increased peak glucagon responses 181 +/- 11 (basal), 214 +/- 16 (rate ...
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The effect of alanine on glucagon secretion
... pancreatic glucagon, was ...in glucagon measured in the pancreaticoduodenal venous plasma; glucagon rose from 350 pg per ml to 1066 pg per ml at the end of the ...
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Direct muscarinic cholinergic inhibition of hepatic glucose production in humans
... increased glucagon secretion with consequent stimulation of glucose production, bethanechol was administered while glucagon levels were held constant with the islet clamp technique (somatostatin ...
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Defective glucose counterregulation after subcutaneous insulin in noninsulin dependent diabetes mellitus Paradoxical suppression of glucose utilization and lack of compensatory increase in glucose production, roles of insulin resistance, abnormal neuroendocrine responses, and islet paracrine interactions
... in glucagon secretion during hypoglycemia occurs primarily via a paracrine islet A-B cell interaction, we examined the effects of a subcutaneously injected therapeutic dose of insulin ...insulin ...
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Characterization of response of circulating glucagon to intraduodenal and intravenous administration of amino acids
... and glucagon from ...and glucagon secretion was achieved during hyperaminoacidemia by infusing ...and glucagon response than could be explained by the ...
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Isosteviol has beneficial effects on palmitate induced cell dysfunction and gene expression
... overall glucagon content was ...enhanced glucagon secretion under conditions of high glucose, while ISV (10 28 M and 10 26 M) had no effect on glucagon secretion during short-term ...
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Somatostatin coordinately regulates glucagon gene expression and exocytosis in HIT T15 cells
... on glucagon exocytosis is preserved in this cell line, whether this effect is mediated through a pertussis toxin-sensitive mechanism, and whether SRIF has an inhibitory effect on glucagon gene ...increased ...
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Factors controlling gastric glucagon release
... gastric glucagon secretion. Under basal conditions, gastric glucagon release was ...ng glucagon/100g of stomach per ...rapid glucagon release. This gastric glucagon release was ...
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Vagal regulation of insulin, glucagon, and somatostatin secretion in vitro in the rat
... and glucagon secretion in proportion to the pulse frequency, but an inhibition in somatostatin ...and glucagon responses to vagal stimulation were partially suppressed, whereas somatostatin release ...
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Fluctuations of calcium, phosphorus, sodium, potassium, and chlorine in single alpha and beta cells during glucose perifusion of rat islets
... microscopy. Over 900 unobscured alpha and beta cells were selected by size and shape criteria. Energy dispersive x-ray analysis was applied to each single cell to determine relative content of calcium (Ca), potassium ...
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Extrapancreatic Glucagon and Glucagonlike Immunoreactivity in Depancreatized Dogs: A QUANTITATIVE ASSESSMENT OF SECRETION RATES AND ANATOMICAL DELINEATION OF SOURCES
... Intestinal glucagon secretion was small and did not respond to arginine, suggesting that the stomach is the only important extrapancreatic source of ...
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Glucose Disposal during Insulinopenia in Somatostatin Treated Dogs: THE ROLES OF GLUCOSE AND GLUCAGON
... and glucagon secretion had been replaced by exogenous intraportal insulin and glucagon infusion after somatostatin inhibition of endogenous pancreatic hormone ...and glucagon (76±3 pg/ml) ...
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Effects of physiologic levels of glucagon and growth hormone on human carbohydrate and lipid metabolism Studies involving administration of exogenous hormone during suppression of endogenous hormone secretion with somatostatin
... of glucagon (1 ng/kg-min) during suppression of its endogenous secretion with somatostatin produced circulating hormone levels of approximately 200 ...When glucagon was infused along with insulin, ...
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Local ventromedial hypothalamus glucose perfusion blocks counterregulation during systemic hypoglycemia in awake rats
... Blood samples for measurement of plasma insulin, glucagon and catecholamines were taken during the euglycemic (30- and 60-min) and hypoglycemic (120-, 135-, and 150-min) phases of the experi- ments. During blood ...
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