glucose-dependent insulinotropic
Single-dose acarbose decreased glucose-dependent insulinotropic peptide and glucagon levels in Chinese patients with newly diagnosed type 2 diabetes mellitus after a mixed meal
... oral glucose administration ...and glucose- dependent insulinotropic peptide ...of insulinotropic actions, or a total loss of GIP effect even with normal levels ...resistance, ...
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Glucose dependent insulinotropic polypeptide receptor deficiency leads to modifications of trabecular bone volume and quality in mice
... A role for the gastro-intestinal tract in controlling bone remodeling is suspected since serum levels of bone remodeling markers are affected rapidly after a meal. Glucose-dependent insulinotropic ...
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Postprandial stimulation of insulin release by glucose dependent insulinotropic polypeptide (GIP) Effect of a specific glucose dependent insulinotropic polypeptide receptor antagonist in the rat
... of glucose and other nutrients is due in part to both hormonal and neural factors ...physiological insulinotropic peptides. After oral glucose administration, serum GIP levels increase several fold ...
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Effects of glucose dependent insulinotropic polypeptide on gastric emptying, glycaemia and insulinaemia during critical illness: a prospective, double blind, randomised, crossover study
... Twenty-four patients were enrolled and no adverse ef- fects (vomiting, hypoglycaemia, seizure or rash) were ob- served with the study drug. Blood results were also reviewed with no unexpected changes to haemoglobin, ...
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Fehlings, Christiane (2010): Physiological and morphological characterization of trangenic pigs expressing a dominant-negative glucose-dependent insulinotropic polypeptide receptor (GIPRdn): a large animal model of diabetes research. Dissertation, LMU München: Tierärztliche Fakultät
... blood glucose concentration is characteristic of the diabetes state and was discovered to derogate β-cell function and trigger β-cell apoptosis (Zhang et ...
168
Herbach, Nadja (2002): Clinical and pathological characterization of a novel transgenic animal model of diabetes mellitus expressing a dominant negative glucose-dependent insulinotropic polypeptide receptor (GIPR dn). Dissertation, LMU München: Tierärztliche Fakultät
... min levels in transgenic animals, however, it is not clear whether the reduced serum albumin levels result from urinary loss of albumin or the catabolic state due to severe weight loss. Another clinically relevant ...
167
Streckel, Elisabeth Therese (2013): Effects of the long-acting glucagon-like peptide-1 receptor agonist liraglutide in adolescent pigs with impaired glucose-dependent insulinotropic polypeptide receptor function. Dissertation, LMU München: Tierärztliche Fakultät
... on glucose homeostasis by enhancing insulin secretion in a glucose dependent manner, reducing postprandial hyperglycemia and suppressing glucagon secretion in humans (Bunck et ...
183
Renner, Simone (2008): Transgenic pigs expressing a dominant-negative glucose-dependent insulinotropic polypeptide receptor: a novel animal model for studying the consequences of impaired incretin hormone function. Dissertation, LMU München: Tierärztliche Fakultät
... However, due to the small number of animals investigated as well as variation of insulin levels of the control group, not all parameters reached statistical significance. Besides the application of a larger animal group, ...
161
The study of metabolic improvement by nutritional intervention controlling endogenous GIP (Mini Egg study): a randomized, cross-over study
... Background: Given the major role of glucose-dependent insulinotropic polypeptide (GIP) in the regulation of adiposity, this study examined the effects induced by a diet based on the Japa[r] ...
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Advanced glycation end products evoke endothelial cell damage by stimulating soluble dipeptidyl peptidase-4 production and its interaction with mannose 6-phosphate/insulin-like growth factor II receptor
... and glucose-dependent insulinotropic polypeptides (GIP) are gut hormones se- creted from L and K cells in the intestine in response to food intake, respectively [12,13], both of which are target ...
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The intestinal distribution pattern of appetite and glucose regulatory peptides in mice, rats and pigs
... and glucose regulatory peptides: glucose-dependent insulinotropic polypeptide (GIP), glucagon- like peptide-1 (GLP-1), glucagon-like peptide-1 (GLP-2), oxyntomodulin/glicentin, neurotensin, ...
6
Glucagon like peptide 1 is a physiological incretin in rat
... Exendin 9-39 at 4.5 nmol/kg had no effect on glucose, arginine, vasoactive intestinal peptide or glucose-dependent insulinotropic peptide stimulated insulin secretion.. Postprandial insu[r] ...
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Comparison of Salivary Glucose and Serum Glucose Concentration in Non-Insulin Dependent Diabetes Mellitus Patients: A Case Control Study
... the glucose concentration in saliva is higher in Diabetic patients than in control subjects with a p value ...salivary glucose levels were clearly higher in Diabetics when compared to the Healthy Non ...
131
DIAGNOSIS AND TREATMENT: SHOULD ORAL HYPOGLYCEMIC AGENTS BE USED IN PEDIATRIC AND PREGNANT PATIENTS?
... blood sugar and abnormal glucose tolerance or cortisone-glucose tolerance tests and dia- betic children in the non-insulin dependent.. phase of a biphasic course might be con-.[r] ...
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The sodium dependent D glucose transport protein of Helicobacter pylori
... In addition to previous findings, where only glucose, and possibly galactose, appeared to be utilised by H. pylori (Mendz et al., 1993; Marais et al., 1999a), we showed for the first time that D-mannose can also ...
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Regulation of glucagon secretion by glucose transporter type 2 (glut2) and astrocyte dependent glucose sensors
... Ripglut1;glut2 –/– mice have no endogenous glucose transporter type 2 (glut2) gene expression but rescue glucose-regulated insulin secretion. Control of glucagon plasma levels is, however, abnormal, with ...
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Glycogen synthase and phosphofructokinase protein and mRNA levels in skeletal muscle from insulin resistant patients with non insulin dependent diabetes mellitus
... nonoxidative glucose metabolism was decreased by 47% (P < ...the glucose oxidation rate was ...by glucose-6- phosphate was 33% lower (P < ...
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“ANTIHYPERGLYCEMIC AND ANTIOXIDANT ACTIVITY OF ETHANOLIC EXTRACT OF MADHUCA LONGIFOLIA BARK” by Srirangam Prashanth*, Annampelli Anil Kumar, Burra Madhu, Yennamaneni Pradeep Kumar, India.
... serum glucose level in normal ...maximum glucose lowering effect, whereas 100 mg/kg of ethanolic extract showed a significant hypoglycemic effect throughout the study ...oral glucose tolerance test, ...
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A fatty acid dependent step is critically important for both glucose and non glucose stimulated insulin secretion
... like glucose, showed an absolute or very strong dependence on FFA for their insulino- tropic action, strongly suggests that fatty acids are involved in activation of a common and permissive step in the secretory ...
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Antidiabetic Activity of Pandanus odoratissimus Root Extract
... A decrease in rat body weight (p < 0.001) was noted in alloxan induced diabetic rat but when the animals were treated with P. odoratissimus extract, the decrease in body weight was completely suppressed and recovery ...
6