Glucose Deprivation
Exon expression in lymphoblastoid cell lines from subjects with schizophrenia before and after glucose deprivation
... or glucose dep- rivation ...× Glucose deprivation effects on expression found in this ...increased glucose utilization [54], as we did not detect an over representation of mitochondrial or ...
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Glucose deprivation promotes apoptotic response to S1 by enhancing autophagy in human cervical cancer cells
... whether glucose deprivation and S1 induced ERS, HeLa cells were treated with EBSS, S1, or EBSS and S1 for 8 ...in glucose-regulated protein-78 (Grp78) using the laser con- focal ...both ...
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Original Article Paeoniflorin down-regulates the expression of NLRP1 and NLRP3 inflammasomes in rat hippocampal slices after oxygen-glucose deprivation
... oxygen- glucose-deprived organotypic hippocampal slice ...oxygen-glucose deprivation (OGD)-induced neuronal cell death and demonstrated the ability to downregulate the levels of the components of ...
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Influence of partial and complete glutamine-and glucose deprivation of breast-and cervical tumorigenic cell lines
... where glucose deprivation in hemapoie- tic ...decreased glucose and L-glutamine quantities resulted in a reduction of the mito- chondrial membrane ...complete glucose starvation for 6 h-9 h ...
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Effect of glutamine or glucose deprivation on the expression of cyclin and cyclin-dependent kinase genes in glioma cell line U87 and its subline with suppressed activity of signaling enzyme of endoplasmic reticulum–nuclei-1
... The major finding reported here is that the expression of most tested genes that encode cyc- lins and cyclin-dependent kinases are dependent on the function of endoplasmic reticulum–nuclei-1 signaling enzyme – both in ...
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Original Article Ginsenoside Rd pretreatment attenuates apoptosis of PC12 cells induced by oxygen-glucose deprivation
... Abstract: The current study explored the inhibitory mechanisms of ginsenoside Rd on apoptosis of PC12 cells in- duced by oxygen-glucose deprivation (hypoxia). An in vitro cell model was established. ...
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Inhibition of IRE1 modifies effect of glucose deprivation on the expression of TNFα-related genes in U87 glioma cells
... We have also demonstrated that the expres- sion of TRADD (TNFRSF1A-associated via death domain) is significantly up-regulated upon glucose deprivation, but only in glioma cells when IRE1 function is ...
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Original Article HRP-3 protects the hepatoma cells from glucose deprivation-induced apoptosis
... during glucose deprivation, HRP-3 stable knockdown and control clones of SMMC-7721 and SK-hep1 were constructed for further analysis in- cluding cellular morphology observation, apoptotic sub G1 peak ...
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Potential role of microRNA-7 in the anti-neuroinflammation effects of nicorandil in astrocytes induced by oxygen-glucose deprivation
... Background: It is generally recognized that the inflammatory reaction in glia is one of the important pathological factors in brain ischemic injury. Our previous study has revealed that opening ATP-sensitive potassium ...
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Original Article Tanshinone IIA pretreatment attenuates oxygen-glucose deprivation induced hippocampal neurons damage
... Abstract: Objective: Tanshinone IIA (Tan IIA) has been used in treatment of ischemic stroke in China. This study was designed to investigate the underlying neuroprotective mechanism of Tan IIA pretreatment in primary ...
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Glucose deprivation in tuberous sclerosis complex-related tumors
... mulated glucose uptake ...upon glucose withdrawal or 2-DG treatment [17]. The combination of low glucose concentration and 2-DG was more effective in limiting ATP, activating AMPK and inducing cell ...
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Oxygen and glucose deprivation induces widespread alterations in mRNA translation within 20 minutes
... Figure 1 In vitro model of ischemia. (A) Analysis of cellular ATP during OGD. Reduction in ATP becomes significant after 2 h. In the presence of glucose, ATP levels remain unchanged. OD, oxygen deprivation. ...
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Original Article Protective effect of catalpol on oxygen glucose deprivation neurons
... Abstract: Brain ischemia is one common cerebrovascular disease with unfavorable prognosis and higher morbidity and mortality rates. The re-perfusion injury after primary ischemia further aggravated the progression of ...
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Inhibition of glucose metabolism prevents glycosylation of the glutamine transporter ASCT2 and promotes compensatory LAT1 upregulation in leukemia cells
... that glucose deprivation by preventing the glycosylation of various proteins including those orchestrating cancer bioenergetics, may also alter glycolysis-independent metabolic routes in tumor ...of ...
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Original Article Eupatilin inhibits OGD/R-induced neuronal injury in PC12 cells
... Abstract: Eupatilin, a pharmacologically active flavone derived from the Artemisia plant species, has been reported to have anti-oxidant, anti-inflammatory, and anti-tumor and neuroprotective activities. Hence, this ...
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Hypoxia and glucose independently regulate the beta adrenergic receptor adenylate cyclase system in cardiac myocytes
... and glucose deprivation, on the beta-adrenergic receptor (beta AR)-adenylate cyclase system in a model of hypoxic injury in cultured neonatal rat ventricular ...mM glucose, cell surface beta AR ...
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Metabolic changes in cancer cells upon suppression of MYC
... (Figure 4c). To determine whether the ROS were required for this increase in cell death, we administered the antioxi- dant NAC upon glucose or glutamine deprivation. How- ever, NAC did not prevent cell ...
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p53-regulated autophagy is controlled by glycolysis and determines cell fate
... How does glycolysis inhibition and/or increased superoxide levels inhibit autophagy in Nutlin treated cells? We carried out electron microscopy to evaluate the relative amount and integrity of autophagic structures after ...
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Maximizing neuroprotection: where do we stand?
... oxygen-glucose deprivation and brief exposure to a high concentration of the NMDA or glutamate provide neuroprotection by reducing the release of glutamate and other EAAs into the extracellular space, thus ...
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Impaired glucose transporter 1 degradation and increased glucose transport and oxidative stress in response to high glucose in chondrocytes from osteoarthritic versus normal human cartilage
... study, glucose deprivation similarly upregulated 2-DG transport (Figure 3) and GLUT-1 protein levels (Figure 4) in normal and OA ...capture glucose and thus to overcome stressful conditions, such as ...
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