Glucose-induced insulin release
The stimulus secretion coupling of glucose induced insulin release Metabolic and functional effects of NH4+ in rat islets
... of glucose-stimulated insulin release by isolated rat ...affect glucose utilization and oxidation, glucose-stimulated proinsulin biosynthesis, the concentration of ATP, AD, and AMP, and ...
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Evidence for the Involvement of Na/Ca Exchange in Glucose induced Insulin Release from Rat Pancreatic Islets
... mM glucose inhibited 45 Ca ++ ...of glucose. The effects of 16.7 mM glucose and ouabain were not additive, indicating that both substances may interfere with Na/Ca ...mM glucose induced ...
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Partial pancreatectomy in the rat and subsequent defect in glucose induced insulin release
... plasma insulin concentrations compared with sham-pancreatectomized ...of insulin, glucagon, and ...intravenous glucose tolerance tests and intravenous arginine challenge given 6-7 wk after surgery, ...
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Diazoxide effects on biphasic insulin release: “adrenergic” suppression and enhancement in the perifused rat pancreas
... An in vitro system for perifusion of rat pancreas has been used to investigate the effects of diazoxide on glucose-induced insulin release. Administration of diazoxide with a stimulating ...
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Epigenetic programming of glucose regulated insulin release
... support glucose homeostasis with great precision by matching insulin release to the metabolic needs of the ...normal glucose-induced insulin release in adult ...
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Glucose Modulation of Amino Acid Induced Glucagon and Insulin Release in the Isolated Perfused Rat Pancreas
... whether glucose (5 mM) was included in the perfusion medium or not. This glucose concentration significantly stimulated insulin release twofold and resulted in an 80% inhibition of basal ...
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The relative roles of calcium, phosphorus, and parathyroid hormone in glucose and tolbutamide mediated insulin release
... on insulin secretion were evaluated in three groups of ...with glucose infusions (group I) or standard intravenous glucose tolerance tests (IVGTT) (group II) before and after the development of ...
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Prolonged exposure of human pancreatic islets to high glucose concentrations in vitro impairs the beta cell function
... high glucose concentrations impairs the function of these ...mM glucose. There was no glucose-induced decrease in islet DNA content or signs of morphological ...mM glucose showed a 45 ...
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A unique control mechanism in the regulation of insulin secretion Secretagogue induced somatostatin receptor recruitment
... marginated to the plasma membrane by glucose, the greater the response to IBMX. Colchicine (1 mM) prevented secretion vesicle migration and this potentiation effect of higher concentrations of glucose was ...
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Insulin and glucose as modulators of the amino acid induced glucagon release in the isolated pancreas of alloxan and streptozotocin diabetic rats
... high glucose but is suppressed by exogenous ...that insulin-dependent glucose transport and metabolism by the alpha-cells serves as the primary mechanism controlling glucagon ...between ...
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Pattern of insulin delivery after intravenous glucose injection in man and its relation to plasma glucose disappearance
... Plasma insulin concentrations after pulse intravenous injection of glucose show an early rise, which declines towards the prestimulation level ...measured insulin disappearance from the plasma of 17 ...
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The Gq/G11 mediated signaling pathway is critical for autocrine potentiation of insulin secretion in mice
... of glucose-induced insulin secretion from isolated β ...increase insulin release from human islets and the murine β cell line MIN6 (29), and shRNA-mediated knockdown of CaR in MIN6 ...
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Cholinergic Modification of Glucose Induced Biphasic Insulin Release in Vitro
... of insulin release. In the absence of glucose the effects of either acetylcholine or acetyl-b-methylcholine were minimal at concentrations up to 10 −5 ...low glucose concentration ...
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Obesity and insulin resistance
... and insulin resistance is dramatic. Leptin treat- ment causes both glucose and insulin levels to fall with- in hours of administration, before changes in either food intake or body weight occur, and ...
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Castration-induced testosterone deficiency increases fasting glucose associated with hepatic and extra-hepatic insulin resistance in adult male rats
... baseline insulin concentrations in castrated rats were higher than those in normal rats, which conformed to the results in non-diabetic men ...However, glucose-stimulated insulin secretion while OGTT ...
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Alterations in basal and glucose stimulated voltage dependent Ca2+ channel activities in pancreatic beta cells of non insulin dependent diabetes mellitus GK rats
... of insulin secretion to nonglucose depolarizing stimuli observed in NIDDM beta cells could be the result, therefore, of increased voltage-dependent Ca2+ channel ...by glucose is markedly less pronounced in ...
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Effects of auditory and visual stimuli on glucose metabolism in Holstein dairy cattle
... on glucose tolerance during short-time exposure in cattle are ...altered glucose metabolism in healthy participants under controlled conditions ...basal glucose concen- trations and elevated ...
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OGTT A PRELIMINARY APPROACH TO DETECT IMPAIRED GLUCOSE TOLERANCE IN CHRONIC PANCREATIC DISORDERS
... Serum insulin test, OGTT, Serum peptide ...decreased insulin production or due to insulin ...post glucose load glucose levels in cases indicate irregularity in glucose ...
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Room-temperature super-extraction system (RTSES) optimizes the anxiolytic- and antidepressant-like behavioural effects of traditional Xiao-Yao-San in mice
... mice for 4 consecutive weeks. The doses of XYS (500 mg/kg/day) and XYS/RTSES (500 mg/kg/day) were two times higher than the maximum recommended human dose of 250 mg/kg/day based on area under the curve (AUC) comparisons. ...
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Effects of Cinnamon on Blood Glucose Level and Lipid Profile in Syrian Type 2 Diabetes Patients
... 22) Vanschoonbeek K, Thomassen BJ, Senden JM, Wodzig WK, van Loon LJ. Cinnamon supplementation does not improve glycemic control in postmenopausal type 2 diabetes patients. J. Nutr., 136, 977-980 (2006). 23) Mang B, ...
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