Glucose output (hepatic)
The Acute Effect of Hydrocortisone on Hepatic Glucose Output and Peripheral Glucose Utilization
... The close correspondence between changes in Mean hepatic glucose output decreased significantly Table II from the control value of 48.5 the hepatic glucose output determined by measmg pe[r] ...
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THE EFFECT OF HEXAMETHONIUM BROMIDE ON SPLANCHNIC BLOOD FLOW, OXYGEN CONSUMPTION AND GLUCOSE OUTPUT IN MAN
... Three or four such determinations were made over twenty minutes and the results averaged to obtain the control values for splanchnic blood flow, hepatic glucose output, arterial lactic a[r] ...
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In vivo kinetics of insulin action on peripheral glucose disposal and hepatic glucose output in normal and obese subjects
... stimulate glucose disposal rate (Rd) and inhibit hepatic glucose output (HGO) in 12 nonobese and 10 obese subjects using the euglycemic clamp technique at insulin infusion rates of 15, 40, ...
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Lipid Transport in the Human Newborn: PALMITATE AND GLYCEROL TURNOVER AND THE CONTRIBUTION OF GLYCEROL TO NEONATAL HEPATIC GLUCOSE OUTPUT
... postabsorptive adult. Approximately 75% of transported glycerol was converted to glucose and represented 5.0±0.6% of hepatic glucose production. Furthermore, there was a direct relationship between ...
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Basal Plasma Glucagon Levels of Man
... Although some increases in phosphorylase activity, hepatic glucose output, and the rate of rise of blood glucose concentration were seen in the seven experiments with human plasma, there[r] ...
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Relationships of generalized and regional adiposity to insulin sensitivity in men
... turnover) to total body adiposity (determined by hydrodensitometry) and regional adiposity. The latter was assessed by determining subcutaneous abdominal, intraperitoneal, and retroperitoneal fat masses (using magnetic ...
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Influence of somatostatin on splanchnic glucose metabolism in postabsorptive and 60 hour fasted humans
... splanchnic glucose output was less than 40% of that observed in the overnight fasted ...of glucose precursors thus exceeded the simultaneous glucose output by more than ...while ...
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Hepatic glucose sensing is required to preserve β cell glucose competence
... i.p. glucose injection (Figure 6, I and J), and was not related to a defect in plasma glucagon levels (Figure 6K), nor was it secondary to the development of insulin resistance as assessed by hyperinsuline- ...
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Effect of Intraduodenal Glucose Administration on Hepatic Extraction of Insulin in the Anesthetized Dog
... after glucose administration, the amount of insulin reaching the liver increased ...the glucose concentration of the femoral artery. After glucose administration, hepatic extraction of insulin ...
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THE PHYSIOLOGICAL SIGNIFICANCE OF THE SECRETION OF ENDOGENOUS INSULIN INTO THE PORTAL CIRCULATION III EVIDENCE FOR A DIRECT IMMEDIATE EFFECT OF INSULIN ON THE BALANCE OF GLUCOSE ACROSS THE LIVER
... Their failure to find a decrease in hepatic glucose output in the two other experiments in which a gradual decline in blood glucose concentration was produced by slow insulin infusion, m[r] ...
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CHLORPROPAMIDE INDUCED LEUCINE HYPOGLYCEMIA
... It is suggested that L-leucine acts similarly in all situations to inhibit hepatic glucose output and that the resultant fall in blood glucose concentration will vary considerably, depen[r] ...
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INFANTS OF DIABETIC MOTHERS: ATTENUATED GLUCOSE UPTAKE WITHOUT HYPERINSULINEMIA DURING CONTINUOUS GLUCOSE INFUSION
... mg/kg/minute, while the rate in the adult dog is about 2 mg/kg/minute.26 In adult dog or man, hepatic glucose output ceases when exogenous glucose is infused at the basal rate.”’7 If glu[r] ...
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Mild type II diabetes markedly increases glucose cycling in the postabsorptive state and during glucose infusion irrespective of obesity
... during glucose infusion (2 mg/kg per ...between hepatic total glucose output (HTGO) (2- [3H]glucose) and hepatic glucose production (HGP) ...With glucose infusion ...
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An energetic tale of AMPK independent effects of metformin
... on hepatic glucose output in primary hepatocytes; rather, their data suggest that the antidiabetic effects of metformin in the liver are mediated directly by reducing energy ...
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Differential Effects of Insulin on Splanchnic and Peripheral Glucose Disposal after an Intravenous Glucose Load in Man
... blood glucose was raised to comparable levels to those of controls ( 170 mg/dl) by a variable glucose ...net output of ...of hepatic glucose output (P < ...splanchnic ...
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Equivalence of the insulin sensitivity index in man derived by the minimal model method and the euglycemic glucose clamp
... the glucose clamp measure equivalent indices of insulin ...Euglycemic glucose clamps (glucose, G: 85 mg/dl) were performed at two rates of insulin (I) infusion (15 and 40 mU/min per m2) in 10 ...
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Effect of prior exercise on the partitioning of an intestinal glucose load between splanchnic bed and skeletal muscle
... intraduodenal glucose infusion. In re- sponse to intraduodenal glucose, arterial plasma glucose rose more in exercised (103 6 4 to 154 6 6 mg/dl) compared with rested (104 6 2 to 139 6 3 mg/dl) ...in ...
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A mathematical model of the euglycemic hyperinsulinemic clamp
... body glucose uptake under hyperinsulinization with respect to a specific and short time frame, then obese sub- jects can be adequately diagnosed by the clamp as being generally insulin ...
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Hepatic glucose sensing: does flux matter?
... of hepatic lipogenesis by glucose and ...direct glucose-sensing function in ...of glucose on genes in the liver (4). The regulation of hepatic lipogenesis involves several ...
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Serial Changes in Norepinephrine Kinetics Associated With Feeding Dogs a High Fat Diet
... In addition, all dogs received vitamin supplements (VAL syrup; Fort Dodge Laboratories, Fort Dodge, IA) and antibiotics throughout the entire study. The dogs were housed in air-conditioned cages and were fed between the ...
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