?- Glucosidase
“Kinetic Parameters of Purified β-glucosidase from the Seeds of Tamarindus indica” by Shlini P, K R Siddalinga Murthy, India.
... Tamarind seed is an underutilized byproduct of the tamarind pulp industry. Only a small portion of the seed, in the form of tamarind kernel powder (TKP), is used as a sizing material in the textile, paper and jute ...
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IN SILICO SCREENING FOR ALPHA GLUCOSIDASE INHIBITORS OF CHROMONE DERIVATIVES
... alpha glucosidase available through the RCSB Protein Data Bank. The compounds were scored based on the minimized ligand protein complexes. New ligands were docked into the empty binding site of alpha ...
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Directed evolution of a fungal β-glucosidase in Saccharomyces cerevisiae
... We targeted the β-glucosidase from A. niger (BGL1) using directed evolution to adapt it towards heterolo- gous expression S. cerevisiae. We built a fusion protein by replacing the native BGL1 signal sequence with ...
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α-Glucosidase inhibitors from the bark of Mangifera mekongensis
... Results: Two new steroids named mekongsterol A (1) and mekongsterol B (2), were isolated from the n-hexane extract of the bark of M. mekongensis (Anacardiaceae), together with seven known compounds (3–9). Their chemical ...
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Secretive expression of heterologous β-glucosidase in Zymomonas mobilis
... Although the secretion ratio of β-glucosidase was still low, it was a significant improvement in Z. mobilis ZM4 compared to the bglB expression by the signal peptide NprB from C. thermocellum, which was almost no ...
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EVALUATION OF α-GLUCOSIDASE, UREASE INHIBITION AND ANTIOXIDANT POTENTIAL OF ACACIA JACQUEMONTII AND RHAMNUS PERSICA.Khuram Ashfaq*, Bashir A choudhary, Muhammad Uzair, Muhammad Naeem Qaisar, Sajid N Hussain1, Muhammad A GhaffariDOWNLOAD/VIEW
... Inhibition of α-glucosidase by dichloromethane and methanol extracts were assayed by previously reported standard method [15]. Sample extract was prepared in 70 % DMSO and 20 μl of that sample was added to 96-well ...
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Purification and characterization of α-glucosidase from Penicillium chrysogenum.
... α -glucosidase is an essential enzyme in the digestion of car- bohydrates. It can release glucose by hydrolyzing linear as well as branched isomaltose oligosaccharides, causin g a postpran- dial hyperglycemia ...
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Diversity of marine bacteria producing beta-glucosidase inhibitors
... inhibitor compounds. Glucosidases are central to carbo- hydrate metabolism and efficient utilization of carbon sources determines the viability of microbes in any envi- ronment. In order to survive in competitive ...
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Hepatitis B Virus Large and Middle Glycoproteins Are Degraded by a Proteasome Pathway in Glucosidase-Inhibited Cells but Not in Cells with Functional Glucosidase Enzyme
... Proteasome inhibitors prevent the glucosidase inhibitor- mediated reductions of LHBs and MHBs proteins in HepG2 2.2.15 cells. Inhibition of ER glucosidases interferes with CNX-mediated folding of some, but not ...
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Alpha Glucosidase Inhibitory Activity of Compounds from Bauhinia strychnifolia
... From bioassay-guided isolation, the water fraction was observed to separate into two compounds namely; 3,5,7- Trihydroxychromone-3-O-α-L-rhamnopyranoside (1) and 3,5,7,3’,5’-pentahydroxy-flavanonol-3-O-α-L- ...
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Alpha-Glucosidase Inhibitory Activity of Garcinia lateriflora Blume Leaves
... Garcinia lateriflora Blume., that belongs to the genus Garcinia, is known to contain polyphenol compounds that are likely to inhibit alpha-glucosidase in the treatment of diabetes mellitus. Therefore, this study ...
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α glucosidase and glycation inhibitory effects of costus speciosus leaves
... The in vitro inhibitory effects of COS leaves on α- glucosidase activity was demonstrated for the first time which may be one mechanism of exerting hypoglycaemic effects of COS leaves in vivo. For the first time ...
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Sorption to Biochar Impacts β-Glucosidase and Phosphatase Enzyme Activities
... α-1,4- glucosidase, β- D -cellobiohydrolase, and β-1,4-N-acetylglucosaminidase, and significantly decreased β-1,4-glucosidase and phosphatase activities ...
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In vitro - glucosidase inhibitory activities of ethonolic extract of Oldenlandia corymbosa
... [11] M. I. Kazeem, J. O. Adamson, and I. A. Ogunwande Modes of Inhibition of α- Amylase and α-Glucosidase by Aqueous Extract of MorindalucidaBenth Leaf BioMed Research InternationaDepartment of Biochemistry, Lagos ...
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A FACILE SYNTHESIS OF TRIAZOLOQUINAZOLINONE DERIVATIVES AS POTENTIAL Α GLUCOSIDASE INHIBITORS
... We have generated 11260 unique scaffolds from our in-house small molecule database, GOSTAR (GVKBIO Online structure Activity Relational Database), and initial screening was carried out using these scaffolds against a ...
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Milk glucosidase activity enables suckled pup starch digestion
... C-LDx. Trunk blood was collected in fluoride/EDTA tubes at 4 °C and spun and frozen at 70 °C until analysis. Enrichments of plasma 13 C-glucose (starch glucogenesis) were measured by gas chromatography combustion iso- ...
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Pseudo deficiency of acid α-glucosidase: a challenge in the newborn screening for Pompe diseases
... α- glucosidase pseudo deficiency from true Pompe disease is important and urgent, as the result generates parental stress and also because this differentiation drives decisions related to the management of the ...
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Assessment of β d glucosidase activity of intact cells of two Oenococcus oeni strains with synthetic and natural substrates
... β-d-Glucosidase activity of SD-2a and 31MBR intact cells with synthetic and natural substrate Oenococcus oeni strains.. β-d-Glucosidase activity synthetic substrate.[r] ...
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Production of B-glucosidase using immobilised Piromyces sp. KSX1 and Orpinomyces sp. 478P1 in repeat-batch culture
... Two anaerobic fungi, one a monocentric strain (Piromyces sp. KSX1) and the other a polycentric strain (Orpinomyces sp. 478P1), were immobilized in calcium alginate beads and cultured in sequential batches where spent ...
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α Glucosidase and β glucosidase from psychrotrophic strain arthrobacter sp C2 2
... In this work six psychophilic and psychrotrophic bacterial strains were screened for the presence of different glycosi- dase activities (α-galactosidase, α-glucosidase, β-glucosidase, α-mannosidase and ...
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