Glutamate Receptors
Glutamate, Glutamate Receptors, and Downstream Signaling Pathways
... pathways. Glutamate signaling activates a family of receptors consisting of metabotropic glutamate receptors (mGluRs) and ionotropic glutamate receptors (iGluRs), both of which ...
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Pharmacology of ionotropic and metabotropic glutamate receptors on neurons involved in feeding behavior in the pond snail, Helisoma trivolvis
... the receptors that mediate this regulation are only partially ...the glutamate receptors on three buccal neurons modulated by ...by glutamate, including that of B27, a phase 2 motor neuron ...
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Postsynaptic glutamate receptors regulate local BMP signaling at the Drosophila neuromuscular junction
... ionotropic glutamate receptors (iGluRs) are heterotetrameric complexes composed of three essential subunits – GluRIIC, GluRIID and GluRIIE – and either GluRIIA or GluRIIB (DiAntonio, ...type-B ...
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L Glutamate Receptors on the Cell Body Membrane of an Identified Insect Motor Neurone
... L-GLUTAMATE RECEPTORS ON THE CELL BODY MEMBRANE OF AN IDENTIFIED INSECT MOTOR NEURONE BY K.. SATTELLE AFRC Unit of Insect Neurophysiology and Pharmacology, Department of Zoology, Univers[r] ...
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No association between Parkinson disease and autoantibodies against NMDA type glutamate receptors
... Parkinson disease (PD) is a neurodegenerative disease. Im- portant components of the pathomechanism are protein aggregation and lysosomal as well as mitochondrial dys- function [1]. Inflammation has been increasingly ...
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Roles of CREB in the regulation of FMRP by group I metabotropic glutamate receptors in cingulate cortex
... metabotropic glutamate receptors (mGluRs) in the central nervous system contribute to higher brain functions including learning/memory, mental disorders and persistent ...
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Glutamate receptors function as scaffolds for the regulation of β-amyloid and cellular prion protein signaling complexes
... to, glutamate receptors (both ionotropic and metabotropic), insulin receptors, acetylcholine receptors (both muscarinic and nicotinic), as well as cellular prion protein (PrP c ) which may ...
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Glutamate Receptors in Nucleus Accumbens Can Modulate Canabinoid-Induced Antinociception in Rat’s Basolateral Amygdala
... that glutamate receptors located in the NAc, partially mediate the antinociceptive responses of cannabinoid within the BLA in persistent inflammatory model of ...
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Differences in glutamate receptors and inflammatory cell numbers are associated with the resolution of pain in human rotator cuff tendinopathy
... Glutamate receptors can be broadly broken down into two major types: ionotropic, which are glutamate-gated ion channels (iGlu), and metabotropic, which are G- protein coupled receptors that ...
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An electrophysical study of synaptic glutamate receptors in cerebellar golgi cells during development
... by glutamate spillover (Clark and Cull-Candy, ...these receptors can activate co localised Ca^^-activated channels (Isaacson and Murphy, ...Metabotropic glutamate receptors (mGluRs), situated ...
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Activation of group II metabotropic glutamate receptors blocks zinc release from hippocampal mossy fibers
... metabotropic glutamate receptors, specifically activated by ...with glutamate, the aim of the work was to investigate the effect of DCG-IV on mossy fiber zinc ...
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The role of metabotropic glutamate receptors and associated cell signaling pathways in the acute sedative-hypnotic effects of ethanol
... amino-acid glutamate is the primary excitatory neurotransmitter in the mammalian central nervous ...system. Glutamate receptors are divided into two categories: ionotropic receptors (iGluRs), ...
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Genetic deletion of mGlu2 metabotropic glutamate receptors improves the short-term outcome of cerebral transient focal ischemia
... metabotropic glutamate receptors protects vulnerable neurons in the 4-vessel occlusion model of transient global ischemia, whereas receptor activation amplifies neuronal ...mGlu2 receptors ...
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Activation of presynaptic ionotropic glutamate receptors stimulates gaba release from hippocampal and cortical rat brain nerve terminals
... presynaptic glutamate receptor activation in the regulation of inhibitory synaptic transmission in the rat hippocampus and ...ionotropic glutamate receptors are involved in the modulation of GABA ...
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[60]Fullerene derivative modulates adenosine and metabotropic glutamate receptors gene expression: a possible protective effect against hypoxia
... derivatives [17,18]. Therefore, [60]fullerene may be con- sider as the ideal candidate for protective properties in liv- ing systems subjected to oxidative stress even though the functionalization of [60]fullerene, used ...
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N methyl D aspartate (NMDA) and non NMDA type glutamate receptors are present on squid giant axon Schwann cells
... Here we present evidence, for the first time in any glial preparation, that NMDA type glutamate receptors are present in the adaxonal glial or Schwann cells of the giant axon of the trop[r] ...
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Targeting metabotropic glutamate receptors for novel treatments of schizophrenia
... orthosteric glutamate binding site among mGlu receptor subtypes has generally precluded the design of subtype-specific receptor agonists or ...mGlu receptors allowing unprecedented selectivity against other ...
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Glutamate Receptors; From Basic Pharmacology To Clinical Applications
... mGlu1 receptors can modulate dopamine ...but glutamate spillover from the corticostriatal synapse could not only activates glutamate receptors on medium spiny neurons, but may also activate ...
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Effects of Trimetaphan on Locust Muscle Glutamate Receptors
... At concentrations >10~ 6 moll~ 1 , concanavalin A blocks desensitization of locust muscle glutamate receptors and it is particularly effective in eliminating desensitization at superfici[r] ...
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Currents mediated by non-NMDA glutamate receptors in rat magnocellular basal forebrain neurones in primary culture
... Divalent cation permeability and double rectification are closely linked in that both are largely determined by the residue occupying the Q/R site (Hume, Dingledine & Heinemann, 1991; Bumashev, Monyer, Seeburg & ...
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