glutamate release
Protease activated receptor 1-induced glutamate release in cultured astrocytes is mediated by Bestrophin-1 channel but not by vesicular exocytosis
... GABA release from cerebellar glia by a direct permeation ...mediates glutamate release from ...-dependent glutamate release mechan- ism in cultured ...PAR1-induced glutamate ...
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Channel-mediated astrocytic glutamate release via Bestrophin-1 targets synaptic NMDARs
... induced glutamate release from astrocytes close to or at the synapse, the astrocytic glutamate does not produce an “ mEPSC-like ” waveform, but instead diffuses slowly at low concentration (1 uM), ...
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Original Article Abnormal glutamate release in aged BTBR mouse model of autism
... tic glutamate receptors and pre-synaptic gluta- mate localized inside ...vesicles. Glutamate binds to glutamate receptors, giving rise to synaptic ...of glutamate release at synaptic ...
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Extrasynaptic glutamate release through cystine/glutamate antiporter contributes to ischemic damage
... alter glutamate homeostasis and whether synaptic or extrasynaptic sites are responsible for excess glutamate remain ...real-time glutamate sensor to identify the source of glutamate ...
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Serotonergic Modulation of Glutamate Release in Layer II of Rat Somatosensory Cortex: Mechanisms and Network Specificity
... transmitter release, the respective dependency on Ca 2+ from extra- and intracellular sources will be ...innervation, release and receptor ...transmitter release via α 1 -adrenoceptors (α 1 -AR), ...
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Further studies on the effects of acamprosate on tolerance to the analgesic effects of morphine and NO synthesis in the brain
... of glutamate release observed during the abstinence period induced by naloxone [24], it is reasonable to expect that the induction of the absti- nence syndrome by naloxone administration should not affect ...
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PubMedCentral-PMC4908643.pdf
... vesicular glutamate type 2 transporter and co-release dopamine and glutamate in a major downstream projection structure — the bed nucleus of the stria ...
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Upregulation of transmitter release probability improves a conversion of synaptic analogue signals into neuronal digital spikes
... Single or multiple spikes in presynaptic pyramidal neurons were evoked by injecting depolarization pulses at 0.1 Hz. Pulse durations were 10 ms with an intensity to initiate single spikes in presynaptic neurons, which ...
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Sexual attraction enhances glutamate transmission in mammalian anterior cingulate cortex
... How could the ACC neurons be activated by sexual attrac- tion? Fos expression is due to the conversion of extracellu- lar signals into early genomic activation, which indicates that a signal transduction event has taken ...
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Modulation of transmitter release at a glomerular synapse in the central nervous system
... of glutamate release is maximal at subthreshold MFS frequencies (<10 ...of glutamate release attenuated the spiking rate at the lower MFS rates of 5 and 10 Hz, at GoS frequencies of 50 and ...
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Stress-induced modulation of endocannabinoid signaling leads to delayed strengthening of synaptic connectivity in the amygdala
... increased glutamate release onto BLA pyramidal neurons in response to stress, we hypothesized that FAAH in- hibition would prevent the delayed synaptic effects of acute stress on BLA neurons 10 d ...
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The role of gliotransmitters in astrocyte driven modulation of synaptic plasticity in the neocortex
... vesicular release of glutamate from nerve terminals ...spontaneous glutamate release activates synaptic NMDARs on post- synaptic neurones ...vesicular release of glutamate (4). ...
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Glutamate receptor-mediated taurine release from the hippocampus during oxidative stress
... of glutamate receptor inhibitors; however, individual contributions of NMDA and AMPA receptors for the swelling response were not elucidated ...metabotropic glutamate receptors in the brain tissue swelling ...
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Protease-activated receptor 2 : are common functions in glial and immune cells linked to inflammation-related CNS disorders?
... and glutamate [102,105] and increasing the expression of astrocytic αA-crystallin ...PAR2-mediated release of chemokines, which is independent of increases in intracellular Ca 2+ [100], is mediated via the ...
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<p>Effect of glutaminase inhibition on cancer-induced bone pain</p>
... target glutamate release from cancer cells associated with clinical CIBP characteristics, we targeted glutamate production at a major metabolic hub that is often associated with the reprogrammed ...
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Ultrafast glutamate sensors resolve high-frequency release at Schaffer collateral synapses.
... image glutamate dynamics in the synaptic cleft, we expressed the newly generated iGluSnFR variants in CA3 pyra- midal cells in organotypic slice culture of rat ...of glutamate release, individual ...
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Modulation of visual processing in the rat superior colliculus by metabotropic glutamate receptors
... * Activation of Group I mGluRs produces mainly inhibitory effects, this inhibition may occur as a result of inhibition of glutamate release from the cortical terminal. An alternative m[r] ...
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Action potential counting at giant mossy fiber terminals gates information transfer in the hippocampus
... synchronous glutamate release at the last sixth ...asynchronous release does not substantially contrib- ute to the depolarization of a postsynaptic cell during short, high- frequency bursts of APs ...
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Glutamate involvement in calcium–dependent migration of astrocytoma cells
... endogenous glutamate release Confluent U-87MG cells plated on glass cover slips were lodged in a 1 x 1 cm cuvette containing Ringer’s solution supplemented with glutamate deshydrogenase (40 U/ml) and ...
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PubMedCentral-PMC4814306.pdf
... Finally, we assessed the capacity of dynorphin neurons in the BNST to release dynorphin following optogenetic stimulation. We stereotaxically injected ChR2 using a Cre-dependent vector (AAV5-EF1α-DIO-ChR2-EYFP) in ...
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