Glutamine Deprivation
Glutamine deprivation plus BPTES alters etoposide- and cisplatin-induced apoptosis in triple negative breast cancer cells
... of glutamine dependence exhibited by cancer cells is specific to the cell type, and glutamine restriction induces distinct reactions in different subtypes of breast tumors ...that glutamine ...
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Expression of ubiquitin specific peptidase and ATG7 genes in U87 glioma cells upon glutamine deprivation
... of glutamine deprivation on the expression of genes encoding for ubiquitin specific peptidases (usP) and ubiquitin activating enzyme E1-like protein/autophagy related 7 (Gsa7/atG7) in u87 glioma cells in ...
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Expression of casein kinase genes in glioma cell line U87: Effect of hypoxia and glucose or glutamine deprivation
... Glutamine deprivation condition also induces the ex- pression of CSNK2A2 both in control glioma cells (+51%) and in ERN1 knockdown cells (+42%), but hypoxia in- duces this mRNA expression in control glioma ...
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ERN1 modifies the effect of glutamine deprivation on tumor growth related factors expression in U87 glioma cells
... upon glutamine deprivation was studied. It was shown that glutamine deprivation down-regulated the expression level of AtF6 (activating transcription factor 6), eIF2Ak3/Perk (eukaryotic ...
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Expression of IGFBP6, IGFBP7, NOV, CYR61, WISP1 and WISP2 genes in U87 glioma cells in glutamine deprivation condition
... upon glutamine deprivation depending on the inhibition of Ire1 (inositol requiring enzyme-1), a central me- diator of endoplasmic reticulum ...upon glutamine deprivation leads to ...
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Effects of glutamine deprivation on oxidative stress and cell survival in breast cell lines
... [3]. Glutamine provides carbon and nitrogen required for the production of energetic-, bio- synthetic- and reductive precursors in tumorigenic cells including deamination of glutamine and subsequent ...
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Asparagine Is a Critical Limiting Metabolite for Vaccinia Virus Protein Synthesis during Glutamine Deprivation
... without glutamine, the rate of protein synthesis is suppressed by a low asparagine supply that cannot support the acute demand for nascent protein synthesis during the brief time window of VACV replication; ...
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Effects of l-Glutamine Deprivation on Growth of HVJ (Sendai Virus) in BHK Cells
... Growth of HVJ in BHK cells cultured in media deprived of various amino acids was investigated, and omission of L-glutamine from culture medium resulted in a marked inhibitory effect on t[r] ...
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Effect of hypoxia and glutamine or glucose deprivation on the expression of retinoblastoma and retinoblastoma related genes in ERN1 knockdown glioma U87 cell line
... glucose deprivation conditions no significant changes were found in the ex- pression level of RNF40 mRNA in both glioma cell types, however, the expression level of this mRNA increases significantly in ...
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Young scientists conference “Modern aspects of Biochemistry and Biotechnology – 2018”
... IRE1. Glutamine is an important factor of glioma development and a more aggressive ...of glutamine deprivation on gene expressions in glioma cells in relation to the func- tional activity of IRE1 ...
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Metabolic changes in cancer cells upon suppression of MYC
... glucose deprivation (Figure ...of glutamine did not prevent cell cycle arrest upon doxycycline adminis- tration, suggesting that providing the end product of glutaminolysis is not sufficient to prevent cell ...
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A Critical Role of Glutamine and Asparagine γ Nitrogen in Nucleotide Biosynthesis in Cancer Cells Hijacked by an Oncogenic Virus
... and glutamine are structurally similar since they both contain amide groups in their respective side ...on glutamine for survival ...to glutamine depletion was not ...upon glutamine ...
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Effect of glutamine or glucose deprivation on the expression of cyclin and cyclin-dependent kinase genes in glioma cell line U87 and its subline with suppressed activity of signaling enzyme of endoplasmic reticulum–nuclei-1
... and glutamine deprivation on the expression of cyclin-dependent kinase-5 (cDk5) mrNa in glioma cell line u87 (control 1) and its subline with signaling enzyme endoplasmic reticulum–nuclei-1 ...
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Influence of partial and complete glutamine-and glucose deprivation of breast-and cervical tumorigenic cell lines
... glucose deprivation in hemapoie- tic ...complete glutamine starvation resulted in mitochondrial ...and glutamine also lead to fused mito- chondria [35]. Glutamine deprivation in human ...
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Is the glutamine story over?
... plasma glutamine [12, 24]. Beyond this, knowledge is scattered. The glutamine concentration at admission to the ward after an ICU stay > 96 hours does not predict outcome ...plasma glutamine ...
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The English Indices of Deprivation 2019 : technical report
... of Deprivation 2000 as the ‘Average Rank’ higher-level summary ...of Deprivation also contained early versions of the higher-level summary measures that were termed ‘Extent’ and ‘Local Concentration’ in the ...
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Endogenous glutamine production in critically ill patients: the effect of exogenous glutamine supplementation
... of glutamine and its relation to plasma glutamine concen- tration is crucial to explore the pivotal role of glutamine in critical ...plasma glutamine concentration is an ominous sign ...plasma ...
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Synergizing metabolic flux analysis and nucleotide sugar metabolism to understand the control of glycosylation of recombinant protein in CHO cells
... mM glutamine was supplied in the culture medium and the structures of the N-linked gly- cans attached to HCG were determined on days 1, 3 and 5 of ...the glutamine concen- tration in the culture medium was ...
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The effect of glutamine administration on urinary ammonium excretion in normal subjects and patients with renal disease
... plasma glutamine concentration fell during acidosis and rose during alkalosis in both healthy subjects and patients with renal ...administered glutamine raised plasma glutamine concentration markedly ...
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Search | Preprints
... hyperammonemic episode. This has not been seen in all patients, especially those with late onset OTCD [15] and suggests neuronal loss or dysfunction. On routine T1 and T2 MRI, there is a relatively normal appearing brain ...
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