Glycoprotein E
Herpes Simplex Virus Type 1 Glycoprotein E Domains Involved in Virus Spread and Disease
... Herpes simplex virus type 1 (HSV-1) glycoprotein E (gE) functions as an immunoglobulin G (IgG) Fc bind- ing protein and is involved in virus spread. Previously we studied a gE mutant virus that was impaired ...
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Bioinformatics analysis and characteristics of envelop glycoprotein E epitopes of dengue virus
... envelope glycoprotein E of dengue (DEN) virus plays a central role in the biology of ...of glycoprotein E ectodomains have already been ...for glycoprotein E which induce the ...
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Bovine Herpesvirus 5 Glycoprotein E Is Important for Neuroinvasiveness and Neurovirulence in the Olfactory Pathway of the Rabbit
... Glycoprotein E (gE) is important for full virulence potential of the alphaherpesviruses in both natural and laboratory hosts. The gE sequence of the neurovirulent bovine herpesvirus 5 (BHV-5) was determined ...
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Composition of Pseudorabies Virus Particles Lacking Tegument Protein US3, UL47, or UL49 or Envelope Glycoprotein E
... or glycoprotein E gene, relative amounts of a capsid protein (UL38), a capsid-associated protein (UL25), several tegument proteins (UL36 and UL47, if present), and glycoprotein H were unaffected, ...
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Mutational analysis of the role of glycoprotein I in varicella-zoster virus replication and its effects on glycoprotein E conformation and trafficking.
... Analysis of the effects of gI deletion on gE trafficking and maturation. Because of the change in growth characteristics of the gI deletion mutants, we used confocal microscopy to ex- amine the effects of removing gI on ...
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Essential Functions of the Unique N-Terminal Region of the Varicella-Zoster Virus Glycoprotein E Ectodomain in Viral Replication and in the Pathogenesis of Skin Infection
... membrane for its complete maturation (20). gE is recycled from the plasma membrane and targeted to the TGN through signal sequences contained in the C terminus (1, 63), which have been identified as the endocytosis motif ...
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Interaction and Interdependent Packaging of Tegument Protein UL11 and Glycoprotein E of Herpes Simplex Virus
... between the gE residues 495 to 550 in contrast to the residues 445 to 472 determined here. This discrepancy likely stems from different systems that were used for mapping the binding do- main. The former was done under ...
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Anterograde Spread of Herpes Simplex Virus Type 1 Requires Glycoprotein E and Glycoprotein I but Not Us9
... To verify that all classes of viral proteins are transported into optic nerve axons in the absence of Us9, brains were stained 5 dpi with antibodies specific to viral glycoproteins, tegument, or capsid (Fig. 6). In ...
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Direct and Specific Binding of the UL16 Tegument Protein of Herpes Simplex Virus to the Cytoplasmic Tail of Glycoprotein E
... The UL16 tegument protein of herpes simplex virus (HSV) is conserved throughout all of the herpesvirus families. Previous studies have shown that the binding of HSV to heparan sulfate molecules on the host cell triggers ...
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Role of the Cytoplasmic Tail of Pseudorabies Virus Glycoprotein E in Virion Formation
... partially sequenced. As summarized in Fig. 4, two deletion events must have occurred during passaging. A 309-bp deletion removed the last 42 nucleotides of the gD gene, resulting in deletion of the carboxy-terminal 14 ...
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Efficient Axonal Localization of Alphaherpesvirus Structural Proteins in Cultured Sympathetic Neurons Requires Viral Glycoprotein E
... to E) or PRV 760 (F to ...G, E, J) either through the plane of the axon (A, C, F, H) or through the plane of the neuron cell body (D, E, I, ...
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Neutrophil neutrophil interactions under hydrodynamic shear stress involve L selectin and PSGL 1 A mechanism that amplifies initial leukocyte accumulation of P selectin in vitro
... mucin glycoprotein can be recognized by all three selectin members, and participates in leukocyte–leukocyte, leukocyte– endothelial cell, and leukocyte–platelet ...
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An Epstein-Barr Virus Isolated from a Lymphoblastoid Cell Line Has a 16-Kilobase-Pair Deletion Which Includes gp350 and the Epstein-Barr Virus Nuclear Antigen 3A
... Epstein-Barr virus (EBV) is associated with human cancers, including nasopharyngeal carcinoma, Burkitt’s lymphoma, gastric carcinoma and, somewhat controversially, breast carcinoma. EBV infects and efficiently transforms ...
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Proteomics computational analyses suggest that the bornavirus glycoprotein is a class III viral fusion protein (γ penetrene)
... BDV glycoprotein (G, GP-C, gp84) migrates due to extensive glycosylation with an apparent molecular mass of 84,000 to 94,000 kilodaltons ...virus glycoprotein transmembrane domain (VSV G TM) domain is ...
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The Human Cytomegalovirus Nonstructural Glycoprotein UL148 Reorganizes the Endoplasmic Reticulum
... Although the capacity of UL148 to retain CD58 may be functionally separable from its peculiar effects on the morphology and organization of the ER, our findings may suggest a mechanism to explain the influence of UL148 on ...
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Impact of Quaternary Organization on the Antigenic Structure of the Tick-Borne Encephalitis Virus Envelope Glycoprotein E
... of E to MAb in the immunocomplexes was determined densitometrically (see Materials and ...the E proteins at the virion surface and steric hindrance between the relatively bulky whole antibody mole- ...
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Use of a Fragment of Glycoprotein G 2 Produced in the Baculovirus Expression System for Detecting Herpes Simplex Virus Type 2 Specific Antibodies
... latent infections. Serology is helpful to confirm clinical cases and to identify latently infected individuals. Type-specific se- rology can be used to identify asymptomatically and subclini- cally HSV-2-infected ...
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Glycoprotein E of Varicella-Zoster Virus Enhances Cell-Cell Contact in Polarized Epithelial Cells
... In cellular adherens junctions, cadherins and actin filaments are aligned in bundles with the plasma membrane (38, 52). Viral pathogens, especially poxviruses, have been shown to manipulate cellular cytoskeletal ...
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Whole-genome sequence of Schistosoma haematobium
... Figure 3 Differential transcription among adult female (F), adult male (M) and egg (E) stages of Schistosoma haematobium. Transcripts (listed by protein name) were mapped to each gene in two dimensions and their ...
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Immunization with a suicidal DNA vaccine expressing the E glycoprotein protects ducklings against duck Tembusu virus
... It has become increasingly accepted that the IFN-γ dependent Th1 cellular response is required for the protec- tion against Flavivirus infection [41–43]. In this study, we also found the ducklings immunized with ...
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