glycyrrhizic acid
Original Article Glycyrrhizic acid inhibits leukemia cell growth and migration via blocking AKT/mTOR/STAT3 signaling
... TF-1 cells were allowed to grow into full conflu- ence in 24-well plates and then wounded by scratching with pipette tips and washed with PBS. Fresh 1640 was added with different con- centrations of glycyrrhizic ...
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Glycyrrhizic acid alters Kaposi sarcoma–associated herpesvirus latency, triggering p53 mediated apoptosis in transformed B lymphocytes
... Kaposi sarcoma–associated herpesvirus (KSHV) is linked with all clinical forms of Kaposi sarcoma and several lymphoproliferative disorders. Like other herpesviruses, KSHV becomes latent in the infected cells, expressing ...
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Lipoprotein lipase expression, serum lipid and tissue lipid deposition in orally-administered glycyrrhizic acid-treated rats
... [14,15]. Glycyrrhizic acid (GA), the primary bioactive constituent of the roots of the shrub Glycyrrhiza glabra and its pharmacologically active metab- olite glycyrrhetic acid (GE) act as potent, ...
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The Review of in Vitro and in Vivo Studies over the Glycyrrhizic Acid as Natural Remedy Option for Treatment of Allergic Asthma
... derivative glycyrrhizic acid may be used for its soothing characteristics as a lenitive compound in skin care applications, whereas the form of salted ammonium or potassium of glycyrrhizic ...
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Enhancing Solubility of Candesartan Cilexetil by Co-milling; Preparation of Candesartan Cilexetil-glycyrrhizic Acid Composite
... 29. Dushkin AV, Tolstikova TG, Khvostov MV, Tolstikov GA. Complexes of polysaccharides and glycyrrhizic acid with drug molecules. Mechanochemical synthesis and pharmacological activity. In: Karunaratne DN, ...
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Effect of Ethanol Concentration in Ultrasound Assisted Extraction of Glycyrrhizic Acid from Licorice Root
... of glycyrrhizic acid (GA) from licorice root powder using water as a solvent ...for glycyrrhizic acid from licorice root and compare this with conventional ...
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Inhibition of the Na+/Ca2+ Exchanger NCX1 Expressed in Xenopus Oocyte by Glycyrrhizic Acid and Cyclophylin A
... In traditional medicine, herbal extracts are often applied in treatment of asthma, and the search for natural components has become promising to dis- cover new anti-asthmatic drugs. Extracts of roots of licorice ( ...
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Glycyrrhizic acid ameliorates myocardial ischemic injury by the regulation of inflammation and oxidative state
... Background: Glycyrrhizic acid (GA), a bioactive triterpenoid saponin isolated from the roots of licorice plants (Glycyrrhiza glabra), has been shown to exert a variety of pharmacological activities and is ...
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Preparation of 10-hydroxycamptothecin-loaded glycyrrhizic acid-conjugated bovine serum albumin nanoparticles for hepatocellular carcinoma-targeted drug delivery
... Taking into account the effects of liver cancer on human health and its difficult treatment, in the study reported here, we attempted to establish a liver cancer-targeted drug deliv- ery system using HCPT to produce 10- ...
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Glycyrrhizic acid improved lipoprotein lipase expression, insulin sensitivity, serum lipid and lipid deposition in high-fat diet-induced obese rats
... Glycyrrhizic acid (GA), a triterpenoid saponin, is the primary bioactive constituent of the roots of the shrub Glycyrrhiza ...glycyrrhetic acid act as potent inhibitors of 11b-HSD1 ...
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Cardioprotective effects of glycyrrhizic acid against isoproterenol-induced myocardial ischemia in rats
... [6,9]. Glycyrrhizic acid (GA) is a triterpenesaponin glycoside, which is the primary bioactive component of the main extract of the root of the plant GlyccyrhizaGlabra (Liquorice), a shrub from the ...
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Mechanism of Glycyrrhizic Acid Inhibition of Kaposi's Sarcoma-Associated Herpesvirus: Disruption of CTCF-Cohesin-Mediated RNA Polymerase II Pausing and Sister Chromatid Cohesion
... Glycyrrhizic acid (GA), a derivative of licorice, selectively inhibits the growth of lymphocytes latently infected with Kaposi’s sarcoma-associated ...
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<p>Glycyrrhizic Acid Inhibits Proliferation of Gastric Cancer Cells by Inducing Cell Cycle Arrest and Apoptosis</p>
... Figure 3 GA suppresses the colony formation ability and proliferation of MGC-803 cells. (A and B) GA suppressed colony formation rate of MGC-803 cells. (C) Single colonies of MGC-803 pretreated with or without GA were ...
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Glycyrrhizic acid nanoparticles inhibit LPS-induced inflammatory mediators in 264.7 mouse macrophages compared with unprocessed glycyrrhizic acid
... Abstract: Glycyrrhizic acid (GA), the main component of radix glycyrrhizae, has a variety of pharmacological activities. In the present study, suspensions of GA nanoparticles with the average particle size ...
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Molecular Docking Studies of Glycyrrhizic acid (GA), Glycyrrhetic acid (GE) and Glabridin (GLA) With Estrogen Receptors (Ers)
... amino acid residues that contributed to hydrophobic interactions in this study such as ALA350, LEU384, LEU391, PHE404, ILE424 and LEU525, were also reported by Wang et ...
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Intestinal absorption and biliary elimination of glycyrrhizic acid diethyl ester in rats
... Liver (200 mg), 50 mM phosphate-buffered solution (pH 7.4, 200 µ L), and stainless steel balls (two balls 3.2 mm in diameter and one ball 5.5 mm in diameter) were added to a 2 mL polyethylene screw vial. The liver tissue ...
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Dihydroisocoumarins from Radix Glycyrrhizae
... including glycyrrhizic acid, glycyrrhetinic acid and flavo- noids including isoliquiritigenin, liquiritigenin, isoliquiri- tin, Licochalcone A, B and E are considered as the main characteristic ...
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Online near-infrared analysis coupled with MWPLS and SiPLS models for the multi-ingredient and multi-phase extraction of licorice (Gancao)
... of glycyrrhizic acid, liquiritin and isoliquiritin were determined by a reversed-phase HPLC assay with analytical ...of glycyrrhizic acid, liquiritin and isoliquiritin were analyzed by ...
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Gas Chromatography-Mass Spectrometry Analysis of the Anti-MRSA Fractions of Chromolaena odorata (L.) R.M. King & H. Rob. leaves
... hexanoic acid (caproic acid), dodecanoic acid (lauric acid), decanoic acid (capric acid) and octanoic acid (caprylic ...octanoic acid and decanoic ...
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Journal of Applied Pharmaceutical Science
... Chlorogenic acid, rosmarinic acid and quinic acid, were found to be the most abundant compound in the methanol extract of ...p-coumaric acid, tr-caffeic acid, apigenin, luteolin and ...
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