GnRH-R
Divergent roles of growth factors in the GnRH regulation of puberty in mice
... the GnRH neuron is not crucial to the function of the GnRH neuron at puberty, as indicated by the normal timing of vaginal opening, first estrus, preputial separa- tion, and AGD in GnRH-IRKO mice ...
11
First in vivo evaluation of a potential SPECT brain radiotracer for the gonadotropin releasing hormone receptor
... HEK293T (division arrested cell-line, Multispan Inc. USA) cells stably expressing GnRH receptors were used to measure the competitive binding for LHRH/GnRH by a fluorescence based FLIPR-assay [12]. ...
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<p>Cardiovascular Risk Profile in Prostate Cancer Patients Treated with GnRH Agonists versus Antagonists: An Italian Real-World Analysis</p>
... between GnRH agonists and ...of GnRH agonists and antagonists on FSH levels or on the GnRH receptor expressed on T ...comparing GnRH agonist and antagonist therapies in PCa patients with a ...
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Strategies for Pituitary Down-regulation to Optimize IVF/ICSI Outcome in Poor Ovarian Responders
... the GnRH receptor to the cell nucleus, and down-regulation of messenger ribonucleic acid (mRNA) expres- sion for the GnRH receptor leading to immediate and rapid suppression of gonadotrophin produc- tion ...
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Gonadotropin releasing hormone receptor mRNA expression by human pituitary tumors in vitro
... gonadotroph adenomas. All tumors had evidence of follicle-stimulating hormone (FSH) beta and alpha subunit biosynthesis using reverse transcriptase/polymerase chain reaction (RTPCR) techniques. Four tumors significantly ...
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Gonadotropin-Releasing Hormone (GnRH) Agonist Trigger in a GnRH Antagonist Protocol and Severe Ovarian Hyperstimulation Syndrome
... when GnRH agonists are administered alone to trigger final oocyte maturation ...a GnRH receptor mutation causes a more lengthy FSH and LH rise after the GnRHa ...
5
Endocrine Disruption and Female Pubertal Timing.
... In contrast to Kp, RFRP3 has inhibitory effects on GnRH release. It has previously been described as having a yin-yang relationship with Kp in regards to pubertal timing, where Kp is the accelerator and RFRP3 is ...
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GnRH analogs for the treatment of symptomatic uterine leiomyomas
... by GnRH agonist treatment [36] should be due to a relative vasoconstriction of myoma- tous vessels [37, 38] and/or to diminished nitric oxide production ...with GnRH-a compared with those receiving placebo ...
7
Decreased FGF8 signaling causes deficiency of gonadotropin releasing hormone in humans and mice
... human GnRH deficiency, including KAL1 (OMIM 308700), GnRH receptor (GNRHR; OMIM 138850), nasal embry- onic LHRH factor (NELF; OMIM 608137), FGF receptor 1 (FGFR1; OMIM 136350), G protein–coupled receptor 54 ...
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Effects of decreasing the frequency of gonadotropin releasing hormone stimulation on gonadotropin secretion in gonadotropin releasing hormone deficient men and perifused rat pituitary cells
... isolated GnRH deficiency who had achieved normal sex steroid levels during prior long-term pulsatile GnRH replacement and (b) perifused dispersed pituitary cells from male rats in the absence of sex ...four ...
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Divergent responses to kisspeptin in children with delayed puberty
... exogenous GnRH, even before priming (mean ± SD ΔLH GnRH ...endogenous GnRH secretion had already “primed” the pituitary gland in these subjects, and, indeed, further pituitary prim- ing with ...
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Using kisspeptin to assess GnRH function in an unusual case of primary amenorrhoea
... hypothalamic GnRH and pituitary gonadotropin ...hypothalamic GnRH release and a GnRH stimulation test to confirm intact pituitary gonadotroph ...test GnRH function in patients presenting with ...
5
Yordanova, Yordanka Zhivkova (2018): Oil-based parenteral depot formulation for veterinary peptide delivery. Dissertation, LMU München: Fakultät für Chemie und Pharmazie
... acting GnRH analogue, GnRH [6-D-Phe] acetate 35,36 .... GnRH [6-D-Phe] acetate is a synthetic superagonistic decapeptide, analogue to the physiological GnRH that possesses greater potency than ...
161
Hormone, behaviour and neuropeptide profiles of normal and stressed ewes
... the GnRH surge ...to GnRH cell bodies and/or ...of GnRH secretion by endogenous opioid systems in the hypothalamus is permissive of the preovulatory GnRH/LH surge (Karla, 1993, Walsh and ...
260
<p>Comparative proteomics reveal negative effects of gonadotropin-releasing hormone agonist and antagonist on human endometrium</p>
... under GnRH-a treatment enriched cytoskeletal regulation (Figure 4C and D), while 151 under GnRH-ant treatment enriched complement-mediated immunity (Figure 4E and ...the GnRH-ant group suggests that ...
9
Pulsatile Hormonal Signaling to Extracellular Signal-Regulated Kinase: Exploring System Sensitivity to Gonadotropin-Releasing Hormone Pulse Frequency and Width
... describing GnRH signaling via the Ca 2⫹ and NFAT pathway and obtained parameter values using a genetic algo- rithm to fit the model to published ERK2-GFP translocation data (Experimental Procedures and Table ...
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Empty Follicle Syndrome Following GnRHa Trigger in PCOS Patients Undergoing IVF Cycles
... pituitary gland may be suppressed from the lack of endogenous GnRH stimulation and thus may not reliably respond to GnRHa administration. Subject 3 with irregular cycles, near normal FSH and LH, AMH-6.9 ng/ml, ...
10
GnRH Agonist and GnRH Antagonist in Intracytoplasmic Injection Cycles
... of GnRH agonist and antagonist in a retrospective study of IVF/ICSI carried out in a tertiary teaching hospital from 2003 to ...68%. GnRH agonist and antagonist cycle parameters were comparable except ...
5
Rahm, Anika Selma Katharina (2017): Vergleich verschiedener Verfahren zur Ovulationssynchronisation und anschließender Besamung bei Altsauen unter Einsatz des GnRH-Analogons Buserelin. Dissertation, LMU München: Tierärztliche Fakultät
... die GnRH-Sekretion und auch das Sexualverhalten stark beeinflussen (THUN, ...Die GnRH-Sekretion ist abhängig von der Dichte der vorhandenen Rezeptoren an den gonadotrophen ...das GnRH selbst ...
141
Improving the reproductive performance of the Muturu breed of cattle in Nigeria using modified Ovsynch and progesterone synchronization protocol : a thesis presented in partial fulfilment of the requirement for the degree of Master of Science in Animal Science, Institute of Veterinary, Animal and Biomedical Sciences, Massey University, Palmerston North, New Zealand
... The study was conducted at Abakiliki in Ebonyi state, Nigeria. Muturu cows (n=100) were selected for the study based on their previous calving history and the presence of follicle of greater than 5 mm diameter. Cows were ...
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