Granulocyte/Macrophage
Association between colony forming units granulocyte macrophage expression of Ia like (HLA DR) antigen and control of granulocyte and macrophage production A new role for prostaglandin E
... units-granulocyte macrophage (CFU-GM) is related to S-phase of the cell cycle, and associated with the control of normal granulocyte and macrophage production by prostaglandin E and acidic ...
12
Expression and Secretion of Human Granulocyte Macrophage-Colony Stimulating Factor Using Escherichia coli Enterotoxin I Signal Sequence
... Human granulocyte macrophage-colony stimulating factor (hGM-CSF) is a glycoprotein consisting of 127 amino acids, including four cysteine residues that provide internal disulfide bridges for the maintenance ...
6
Cytokines in chronic inflammatory arthritis V Mutual antagonism between interferon gamma and tumor necrosis factor alpha on HLA DR expression, proliferation, collagenase production, and granulocyte macrophage colony stimulating factor production by rheumatoid arthritis synoviocytes
... and granulocyte macrophage colony-stimulating factor [GM-CSF] production) and phenotype (expression of class II MHC antigens) of cultured fibroblast-like RA ...and macrophage colony-stimulating ...
10
A study of the granulocyte-macrophage colony stimulating factor receptor (GM-CSFR) in leukaemia
... RNA from six patients with the rare paediatric disorder JCML was screened for mutations in the coding sequence of both the a and p chain of the GM -CSFR using SSCP analysis and the results are presented in Chapter 4. The ...
176
Parathyroid hormone and lipopolysaccharide induce murine osteoblast like cells to secrete a cytokine indistinguishable from granulocyte macrophage colony stimulating factor
... unknown cytokines, we have induced primary murine osteoblasts with two bone active agents, parathyroid hormone (PTH) and lipopolysaccharide (LPS) and analyzed the conditioned media (CM) for the presence of specific ...
10
Identification of a Siglec F+ granulocyte macrophage progenitor
... erythroid, granulocyte, eosinophil, macrophage, megakaryocyte, and blast ...granulocytic, macrophage, and granu- locyte/macrophage colonies ...
11
Granulocyte macrophage colony stimulating factor induces cytokine secretion by human polymorphonuclear leukocytes
... Granulocyte-macrophage colony-stimulating factor (GM-CSF) is known as an inducer of proliferation and functional activation of myeloid cells. This study was carried out to characterize the effects of GM-CSF ...
6
A Randomized Trial of Granulocyte-Macrophage Colony-Stimulating Factor in Neonates With Sepsis and Neutropenia
... Conclusion. Treatment with rhGM-CSF is associated with an increase in absolute neutrophil, eosinophil, monocyte, lymphocyte, and platelet counts and de- creased mortality in critically ill septic neutropenic neo- nates. ...
8
Cryptococcus deuterogattii VGIIa Infection Associated with Travel to the Pacific Northwest Outbreak Region in an Anti Granulocyte Macrophage Colony Stimulating Factor Autoantibody Positive Patient in the United States
... ABSTRACT The region encompassing the Pacific Northwest (PNW), Vancouver Is- land, Oregon, and Washington has been the location of an ongoing Cryptococcus gattii outbreak since the 1990s, and there is evidence that the ...
14
Role of Granulocyte Macrophage Colony Stimulating Factor Production by T Cells during Mycobacterium tuberculosis Infection
... Here, we tested the hypothesis that T cell production of GM-CSF contributes to host resistance to M. tuberculosis. We found that numerous T cell subsets, including both conventional and unconventional T cells, produce ...
18
Isoforms of the granulocyte-macrophage colony-stimulating factor receptor
... binding... Possible mechanisms by which GM-CSFRa4 could give rise to intermediate affinity GM-CSF binding. A) Insertion of 34 amino acids in the membrane proximal re[r] ...
240
Description and outcome of a cohort of 8 patients with WHIM syndrome from the French Severe Chronic Neutropenia Registry
... CXCL12: Chemokine (C-X-C motif) ligand 12; ELANE: Elastase neutrophil expressed; EBV: Epstein Barr virus; GCSF: Granulocyte colony-stimulating factor; GMCSF: Granulocyte macrophage colon[r] ...
14
Immune-based therapies for metastatic prostate cancer: An update
... : Combined immunotherapy with granulocyte-macrophage colony-stimulating factor-transduced allogeneic prostate cancer cells and ipilimumab in patients with metastatic castration-resista[r] ...
30
Progress on new vaccine strategies for the immunotherapy and prevention of cancer
... Induction of immunity to prostate cancer antigens: results of a clinical trial of vaccination with irradiated autologous prostate tumor cells engineered to secrete granulocyte-macrophage[r] ...
12
Safety and immunologic correlates of Melanoma GVAX, a GM CSF secreting allogeneic melanoma cell vaccine administered in the adjuvant setting
... irradiated granulocyte–macrophage colony stimulating factor (GM-CSF)-secreting allogeneic whole-cell melanoma vaccine which was administered in the adjuvant setting to patients with high-risk, surgically ...
14
Myeloid-derived suppressor cells in hematological malignancies: friends or foes
... G-CSF: Granulocyte colony- stimulating factor; GM-CSF: Granulocyte-macrophage colony-stimulating fac- tor; G-PBSC: G-CSF peripheral blood stem cells harvest; GRFS: GVHD and relapse-free survival; ...
12
Effects of immunotherapy on mortality in neonates with suspected or proven sepsis: a systematic review and network meta-analysis
... (IgGAM), granulocyte-colony stimulating factor (G-CSF), granulocyte-macrophage colony stimulating factor (GM-CSF) and human antibodies to endotoxin (antilipo- polysaccharide), have been evaluated for ...
10
Effect of hematopoietic growth factors on human blood monocytes/macrophages in in vitro culture.
... The addition of macrophage CSF, granulocyte-macrophage CSF, and granulocyte CSF and interleukin-6 and interleukin-3 growth factors to monocyte/macrophage cultures induced morphological c[r] ...
6
An Update on Pathophysiology and Medical Management of Endometriosis
... Abbreviations NFκB—Nuclear factor kappa B; MIF—Macrophage migration inhibiting factor; MCP1—Monocyte chemoattractant protein; GM-CSF—Granulocyte macrophage colony stimulating factor; TNF[r] ...
21
Elevated levels of CXCL10 in the Periodic Fever, Aphthous stomatitis, Pharyngitis and cervical Adenitis syndrome (PFAPA) during and between febrile episodes; an indication of a persistent activation of the innate immune system
... G-CSF: Granulocyte colony-stimulating factor; GM-CSF: Granulocyte macrophage colony- stimulating factor; Ig: Immunoglobulin; INF: Interferon; IL: Interleukin; PDGF: Platelet-derived growth factor; ...
10