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granulosa cell tumor

Granulosa-cell tumor of the ovary

Granulosa-cell tumor of the ovary

... : Granulosa cell tumors of the ovary are rare, and included in the sex cord-stromal tumor ...of granulosa cell tumor of the adult and a review of the literature, we will describe ...

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Adult type granulosa cell tumor of the testis with a heterologous sarcomatous component: case report and review of the literature

Adult type granulosa cell tumor of the testis with a heterologous sarcomatous component: case report and review of the literature

... testicular granulosa cell tumors are rare sex cord- stromal tumors of which only 45 have been previously ...type granulosa cell tumor with a heterologous sarcomatous tumor ...

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Adult granulosa cell tumor associated with endometrial carcinoma: a case report

Adult granulosa cell tumor associated with endometrial carcinoma: a case report

... Adult granulosa cell tumors account for approximately 95% of all granulosa cell tumors ...juvenile granulosa cell tumor at our center. Adult granulosa cell ...

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Molecular pathogenesis in granulosa cell tumor is not only due to somatic FOXL2 mutation

Molecular pathogenesis in granulosa cell tumor is not only due to somatic FOXL2 mutation

... diagnosed tumor type within sex cord-stromal category is the granulosa cell tumor ...[1]. Granulosa cell tumors may be composed almost exclusively of granulosa cells, but ...

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Adult-type granulosa cell tumor of the testicle: case report

<p>Adult-type granulosa cell tumor of the testicle: case report</p>

... The fi rst testicular granulosa cell tumor (GCT) was reported by Laskowski et al in 1952. 1 From that time on, two distinct types of testicular GCT have been identi fi ed in men: the juvenile type ...

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PMS2 gene mutation results in DNA mismatch repair system failure in a case of adult granulosa cell tumor

PMS2 gene mutation results in DNA mismatch repair system failure in a case of adult granulosa cell tumor

... In our previous study [9], we reported an 80-year-old woman with a granulosa cell tumor arising from the ovary. Molecular studies showed a heterozygous FOXL2 402C > G mutation in the tumor ...

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Collision tumor of the colon – colonic adenocarcinoma and ovarian granulosa cell tumor

Collision tumor of the colon – colonic adenocarcinoma and ovarian granulosa cell tumor

... A 64 year old woman presented with small bowel obstruc- tion and a pelvic mass. Her significant past history included a bilateral salpingo-oophrectomy with hysterec- tomy sixteen years ago which on retrospective ...

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MR findings of primary ovarian granulosa cell tumor with focus on the differentiation with other ovarian sex cord-stromal tumors

MR findings of primary ovarian granulosa cell tumor with focus on the differentiation with other ovarian sex cord-stromal tumors

... ovarian granulosa cell tumor were retrospectively reviewed by two radiologists with consensus ...ovarian granulosa cell tumors were detected on ...

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Luteinizing hormone elevation in ovarian granulosa cell tumor: a case report and review of the literature

Luteinizing hormone elevation in ovarian granulosa cell tumor: a case report and review of the literature

... In addition, monitoring serum LH is necessary and may provide additional tumor markers for such cases after conservative surgery. Patients should also pay attention to the regularity of their cycles, which may be ...

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Is adjuvant chemotherapy beneficial for patients with FIGO stage IC adult granulosa cell tumor of the ovary?

Is adjuvant chemotherapy beneficial for patients with FIGO stage IC adult granulosa cell tumor of the ovary?

... This study raises questions over the importance of chemotherapy in patients with stage IC AGCT. The lack of any obvious benefit of adjuvant chemotherapy sug- gests that new effective treatment modalities are needed, ...

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Clinicopathological characteristics and prognosis of adult ovarian granulosa cell tumor: a single-institution experience in China

Clinicopathological characteristics and prognosis of adult ovarian granulosa cell tumor: a single-institution experience in China

... A total of 141 patients underwent surgical treatment for AGCT in Peking Union Medical College Hospital during the study period. The mean age of the patients was 45.1 years (16–78 years), and 46 patients (32.6%) were ...

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Rapidly growing juvenile granulosa cell tumor of the ovary arising in adult: a case report and review of the literature

Rapidly growing juvenile granulosa cell tumor of the ovary arising in adult: a case report and review of the literature

... the tumor showed multiloculated cystic mass with intracystic hemorrhage on the ...of tumor demonstrated high signal intensities ...the tumor, such as Call-Exner bodies and “coffee-bean” ...

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The molecular mechanism of ovarian granulosa cell tumors

The molecular mechanism of ovarian granulosa cell tumors

... cancer cell lines when the BMP signal components are ...ovarian granulosa cells of mice were involved in the development of GCT ...of granulosa cell tumor proliferation ...KGN ...

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Clinicopathological spectrum of ovarian sex cord-stromal tumors; 20 years’ retrospective study in a developing country

Clinicopathological spectrum of ovarian sex cord-stromal tumors; 20 years’ retrospective study in a developing country

... adult granulosa cell ...the granulosa cell tumors were not infrequent, encountered in 5 patients, which re-emphasizes the need for long term follow-up of these patients ...

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Laparoscopic restaging of ovarian granulosa cells tumor: three cases report

Laparoscopic restaging of ovarian granulosa cells tumor: three cases report

... Abstract Granulosa cell tumor (GCT) of the ovary is an uncommon neoplasm, often diagnosed at an early stage. Surgery is necessary for definitive diagnosis and staging. Complete staging is recommended ...

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Constitutively active transforming growth factor β receptor 1 in the mouse ovary promotes tumorigenesis

Constitutively active transforming growth factor β receptor 1 in the mouse ovary promotes tumorigenesis

... the granulosa cell tumors of Bmpr1a/Bmpr1b conditional knockout mice ...in granulosa cell tumor development seems ...human granulosa tumor cells ...

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Evaluation of Ovarian Lesions Inducing Endometrial Hyperplasia or Carcinoma in a Tertiary Care Hospital in Southern India

Evaluation of Ovarian Lesions Inducing Endometrial Hyperplasia or Carcinoma in a Tertiary Care Hospital in Southern India

... benign tumor of stromal cell origin that represents 1% of all ovarian tumors is encountered more often in women of perimenopausal and postmenopausal ...of granulosa cell tumor with ...

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A possible role for AMP-activated protein kinase activated by metformin and AICAR in human granulosa cells

A possible role for AMP-activated protein kinase activated by metformin and AICAR in human granulosa cells

... KGN cell line to investigate whether AICAR could prevent inflammatory mediator production, given its role in the regulation of granulosa ...human granulosa cell tumor were treated with ...

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Mitochondrial membrane depolarization enhances TRAIL-induced cell death in adult human granulosa tumor cells, KGN, through inhibition of BIRC5

Mitochondrial membrane depolarization enhances TRAIL-induced cell death in adult human granulosa tumor cells, KGN, through inhibition of BIRC5

... pathogenic, the mechanisms by which FOXL2 C134W drive tumorigenesis are not well characterized, but set this tumor type apart from not only the juvenile subtype, but ovarian cancers of epithelial origin as well ...

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Virilizing form of ovarian juvenile granulosa tumor: A case report

Virilizing form of ovarian juvenile granulosa tumor: A case report

... Nous rapportons un nouveau cas colligé au service de Gynécologie Obstétrique (HMIMV) d'une forme virilisante des tumeurs juvéniles de la granulosa, découverte à l’occasion d’une exacerbation récente d'un syndrome ...

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