Granulosa Cell Tumors
Transcriptomic analysis of stage 1 versus advanced adult granulosa cell tumors
... Ovarian granulosa cell tumors (GCT) are hormonally-active neoplasms characterized, in the adult-subtype, by a mutation in the FOXL2 gene ...stage tumors die from their disease; aside from ...
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Diagnostic relevance of urinary steroid profiles on ovarian granulosa cell tumors: two case reports
... Background: Granulosa cell tumor of the ovary is the most frequent sex cord stromal tumor and represents 2 to 5% of all primary ovarian ...Ovarian granulosa cell tumor is a malignant tumor ...
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Ovarian granulosa cell tumors: a retrospective study of 27 cases and a review of the literature
... ovarian granulosa cell tumors: Ki67 – 1 and p53 immunohistochemistry demonstrates a possible molecular basis for the poor histopathologic prediction of clinical ...
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Bilateral granulosa cell tumors: a novel malignant manifestation of multiple endocrine neoplasia 1 syndrome found in a patient with a rare menin in-frame deletion
... malignant tumors of the endocrine ...carcinoid tumors commonly originating in the colon, thymus, and ...bilateral granulosa cell ovarian tumors, and which is associated with a rare ...
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Expression of CD56 isoforms in primary and relapsed adult granulosa cell tumors of the ovary
... CD56 is constantly expressed in adult granulosa cell tumors of ovary. Its expression is most probably deter- mined by tumor histogenesis. Therefore, apart from other immunohistochemical markers like ...
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Presentation of two patients with malignant granulosa cell tumors, with a review of the literature
... Granulosa cell tumors (GCTs) of the ovary comprise 2 to 5% of malignant ovarian tumors [1,2], and 20 to 30% show malignant clinical and histopathological characteris- ...for tumors at ...
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Inhibitor of apoptosis proteins are potential targets for treatment of granulosa cell tumors – implications from studies in KGN
... Background: Granulosa cell tumors (GCTs) are derived from proliferating granulosa cells of the ovarian ...of tumors, analogs of the second mitochondria-derived activator of caspases ...
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The molecular mechanism of ovarian granulosa cell tumors
... GCT incidence of ovarian cancer accounts for about 2% to 5%, while the prognosis is usually better. Five-year survival rate is up to 90%. High recurrent rate is the most critical factor for GCT death. At present, the ...
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Clinicopathological spectrum of ovarian sex cord-stromal tumors; 20 years’ retrospective study in a developing country
... stromal tumors were ...stromal tumors, most common was adult granulosa cell tumor ...Juvenile granulosa cell tumors were retrieved ...sertoli-leydig cell ...
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Granulosa-cell tumor of the ovary
... : Granulosa cell tumors of the ovary are rare, and included in the sex cord-stromal tumor ...hormone-secreting tumors of the ovary and may lead to suggestive clinical ...of granulosa ...
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Collision tumor of the colon – colonic adenocarcinoma and ovarian granulosa cell tumor
... collision tumors it is important to exclude rare tumors resulting from one can- cer metastasizing to one ...dormant granulosa tumor cells resulting in a sixteen year delayed ...recurrence. ...
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MR findings of primary ovarian granulosa cell tumor with focus on the differentiation with other ovarian sex cord-stromal tumors
... ovarian granulosa cell tumor were retrospectively reviewed by two radiologists with consensus ...ovarian granulosa cell tumors were detected on MRI. Sixteen tumors appeared as ...
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Adult granulosa cell tumor associated with endometrial carcinoma: a case report
... Granulosa cell tumors cause endometrial cancer by virtue of continuous and unopposed estrogen secretion by the ovary ...that tumors be graded using both architectural and nuclear ...of ...
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Histopathological profile of ovarian tumors in a tertiary care centre in Kerala: a retrospective two year study
... ovarian tumors were ...ovarian tumors. Majority of ovarian tumors were seen in the age group of 40-49 years (24%) and least below 10 years ...germ cell tumors ...germ cell ...
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Clinicomorphological study of ovarian tumours: two year study
... clear cell carcinoma ...epithelial tumors (5.8%) (Figure 3). Malignant sex cord stromal tumors constituted ...adult granulosa cell tumors (13%), fibrosarcoma ...steroid ...
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<p>Adult-type granulosa cell tumor of the testicle: case report</p>
... differentiated granulosa cells. Granulosa cells are distin- guished by their “ coffee-bean nuclei ” ; oval-shaped nuclei with a central groove, resembling a ...stromal tumors, with only a few ...
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Histopathological spectrum of ovarian tumors a two year experience at a tertiary care hospital
... : Ovarian cancer encompasses a heterogenous group of malignancies that vary in etiology, molecular biology, and numerous other characteristics. Their complex nature, unpredictable behaviour, prognosis and varying ...
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Expression of pluripotency markers in human granulosa cells after embryonic stem cell extract exposure and epigenetic modification
... Luteinizing granulosa cells have been considered as terminally differentiated ...the granulosa cells could lose their specific markers and express Oct4 but not the other pluripotent markers ...non-treated ...
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Oleic acid induces down-regulation of the granulosa cell identity marker FOXL2, and up-regulation of the Sertoli cell marker SOX9 in bovine granulosa cells
... [6]. Sahmi et al. [7] showed that the transcription factor and GC identity marker FOXL2 is vital for higher activity of the CYP19A1 promoter P2 in bovine GC. So we hy- pothesized that OA may affect the expression of ...
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MicroRNAs in ovarian follicular atresia and granulosa cell apoptosis
... These studies applied microRNA sequencing, micro- array or PCR array methods and provided useful candi- dates for further studies, which may lead to the identification of biomarkers for medical diagnosis in ovar- ian ...
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