growth cone
Agrin regulates growth cone turning of Xenopus spinal motoneurons
... in growth cones in response to extracellular signals (Lundquist, ...the growth cone may result in a gradient of actin filament polymerization, with reduced polymerization and a lower level of ...
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Axon guidance receptors direct growth cone pathfinding: rivalry at the leading edge
... Studies in both invertebrates and vertebrates have lead to a synergistic model of axon guidance in which distinct guidance cues cooperate to steer axons through complex microenvironments to their final target. The ...
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Neukirchen, Dorothee (2010): CLIPs regulate neuronal polarization through microtubule and growth cone dynamics. Dissertation, LMU München: Fakultät für Biologie
... axonal growth cone. Due to their localization, CLIPs could directly affect the actin cytoskeleton by enabling the microtubule-actin interaction. To manage an interaction between microtubules and the actin ...
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Regulation of ECM degradation and axon guidance by growth cone invadosomes
... Another crucial open question is what roles do invadosomes have in the guidance of axons and dendrites to their synaptic targets? One possible function of invadosomes is the targeting of MMPs and other proteases, such as ...
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Growth cone-specific functions of XMAP215 in restricting microtubule dynamics and promoting axonal outgrowth
... in growth cones that accounts for the velocity change? Given the current understanding of XMAP215 activity, one simple hypothesis was that XMAP215, which contains multiple tubulin dimer-binding TOG domains, might ...
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Homer, TRP channels and calcium : the signalling triad of growth cone motility
... The regulation of growth cone motility by BDNF is calciumdependent Song etal., 1997 and recent experiments have confirmed that transient receptor potential channels TRPC contribute to BD[r] ...
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MIG 15 and ERM 1 promote growth cone directional migration in parallel to UNC 116 and WVE 1
... the growth cone in response to the attractive netrin cue (Adler et ...the growth cone away from the UNC-6 repellent in dorsal-directed axon ...
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Original Article Sema3F downregulates p53 expression leading to axonal growth cone collapse in primary hippocampal neurons
... axonal growth cone collapse via downregulation of p53 ...Sema3F-induced growth cone collapse, including Rho kinase, GTP kinase and cGMP ...Semaphorin-induced growth cone collapse ...
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Control of Growth Cone Polarity, Microtubule Accumulation, and Protrusion by UNC-6/Netrin and Its Receptors in Caenorhabditis elegans
... the growth cone regulated by UNC-6/Netrin signaling during outgrowth are incompletely ...in growth cones migrating away from UNC-6/Netrin, the receptor UNC-5 regulates growth cone ...
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Electrical activity, growth cone motility and the cytoskeleton
... the growth cone that reaches its target seems to send a retrograde message causing the neurone to retract other projections (Jellies et ...the growth cone that reaches its target collapses and ...
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Growth cone navigation in substrate bound ephrin gradients
... permanent growth cone collapse or adhesion to high amounts of substrate-bound ephrin, but rather a dynamic ...retinal growth cones (Weinl et ...transient growth cone collapse followed ...
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The dynamics of growth cone morphology
... extract growth cone outlines, a quadrilateral region of interest was manually placed over the growth cone for selected frames of each movie and then automatically interpo- lated for ...
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SRC 1, a non receptor type of protein tyrosine kinase, controls the direction of cell and growth cone migration in C elegans
... the growth cones to reach the anterior body ...PVM growth cones in the src-1(cj293) mutant fail to respond to the guidance cues that direct their migration along the anteroposterior ...PVM growth ...
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RPM 1 regulates axon termination by affecting growth cone collapse and microtubule stability
... how growth cone collapse occurs prior to axon termination in ...the growth cone transitioning from a dynamic to a static state. Growth cone collapse prior to termination is ...
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Homer regulates calcium signalling in growth cone turning
... in growth cones to regulate crucial aspects of calcium signalling in response to guidance cue receptor ...of growth cones to external guidance cues [63] and their reliance on intracellular calcium ...
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Pioneer growth cone migration in register with orthogonal epithelial domains in the grasshopper limb bud
... Int J Dev BioI 39 965 973 (1995) 965 Original Article Pioneer growth cone migration in register with orthogonal epithelial domains in the grasshopper limb bud MATTHEW A SINGER', TIMOTHY P O'CONNOR' an[.] ...
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Substrate interactions affecting motor growth cone guidance during development and regeneration
... Motoneurones located in the centre of the brachial spinal cord the location normally occupied by triceps motoneurones selectively reinncrvated the triceps muscles after crushing the vent[r] ...
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Mitochondrial movement and positioning in axons: the role of growth factor signaling
... to growth cone activity, both the amount of anterograde motor activity and the balance between stationary and motile mitochondria change (Morris and Hollenbeck, 1993; Hollenbeck, ...
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Financial Intermediation and Economic Growth: Bank Credit Maturity and Its Determinants
... to growth cones of identified Helisoma buccal neurons B5 in vitro induces an increase in filopodial length, a decrease in filopodial number, and a slowing in neurite ...affect growth cone ...on ...
203
Different species of phosphatidic acid are produced during neuronal growth and neurosecretion
... neuronal growth factor (NGF), which have been widely used as a model to assess neurite outgrowth, we found that the PA sensor Spo20p-GFP accumulated at the plasma membrane following NGF stimulation as well as at ...
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