growth plate
Triiodothyronine stimulates maturation of porcine growth plate cartilage in vitro
... since growth-plate cartilage alkaline phosphatase activity was not increased by cortisol, insulin, parathyroid hormone, or 5% fetal calf ...of growth-plate cartilage showed that T3 in a ...
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Automated Cell Detection and Morphometry on Growth Plate Images of Mouse Bone
... mouse growth plates is extensively used in biology to understand the effect of specific molecules on various stages of normal bone development and on bone ...the growth plate and heterogeneity of ...
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Altered Cellular Kinetics in Growth Plate according to Alterations in Weight Bearing
... the growth plate metabolism, a simulated animal model of weightlessness was introduced and the chondrocytes’ cellular kinetics was ...the growth plate, 5-bromo-2’-deoxyuridin ...
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Noncanonical frizzled signaling regulates cell polarity of growth plate chondrocytes
... Our gene expression analysis also showed that some components of the noncanonical planar cell polarity (PCP) pathway (Klein and Mlodzik, 2005) are expressed in the developing growth plate (Fig. 5J). The ...
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Indian hedgehog stimulates periarticular chondrocyte differentiation to regulate growth plate length independently of PTHrP
... Hedgehog directly stimulates differentiation of periarticular chondrocytes into columnar chondrocytes. In order to further determine whether Ihh directly acts on periarticular chondrocytes to stimulate differentiation ...
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c Raf promotes angiogenesis during normal growth plate maturation
... promotes growth plate maturation by regulating VEGF protein levels in hypertrophic chondrocytes (Ivkovic et ...in growth plate maturation and vascular invasion by attenuating ubiquitin- ...
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Altered Cellular Kinetics in the Growth Plate of the Femoral Head of Spontaneously Hypertensive Rats
... Our study had several limitations, even though we adjust- ed for various limitations by incorporating a large number of animals in the study. First, to evaluate adverse effects on the growth plate, we ...
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The epiphyseal growth plate and peripheral cartilaginous tumours : the neighbours matter
... fibroblast growth factor 2 signal transduction, which may impair chondrocyte ...the growth plate is required to escape the proteoglycan gradient generated by neighbouring cells and give rise to ...
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Persistent expression of Twist1 in chondrocytes causes growth plate abnormalities and dwarfism in mice
... additional growth plate abnormalities in Col2-Twist1 transge- nics, including blood vessel and focal bony formation within the cartilaginous ...including growth retardation, decreased PCNA-stained ...
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BMP Receptor 1A Determines the Cell Fate of the Postnatal Growth Plate
... bone growth after Bmpr1a is removed postnatally from the progenitor cells in the growth ...null growth plate is gradually replaced by bone and fiber-like ...the growth plate is ...
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A dynamic cell adhesion surface regulates tissue architecture in growth plate cartilage
... the growth plate cartilage promotes bone elongation via regulated chondrocyte maturation within an ordered, three-dimensional cell ...three-dimensional growth plate ...
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Cyclooxygenases and prostaglandin E2 receptors in growth plate chondrocytes in vitro and in situ – prostaglandin E2dependent proliferation of growth plate chondrocytes
... intact growth plate in situ in comparison with the expression in cultured growth plate ...the growth plate, COX-2 showed moderate expression in the reserve zone and strong ...
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Fibroblast growth factor receptor 3 effects on proliferation and telomerase activity in sheep growth plate chondrocytes
... Growth plate chondrocytes exhibit reduced prolifera- tive capacity and cellular senescence as animals advance through puberty ...in growth plate chondrocytes is not well understood, human ...
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The tibial growth plate as a predictor of the original tibial plateau joint line as a reference for kinematically aligned total knee arthroplasty
... proximal growth plate (GP) of the tibia can provide a potential base of reference to original articular surface of the tibial plateau (TP), since the GP is relatively easy to visualize in 3D from computed ...
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Differential effects of insulin like growth factor I and growth hormone on developmental stages of rat growth plate chondrocytes in vivo
... Skeletal growth depends upon enchondral ossification in growth plate cartilage, within which chondrocytes undergo well defined stages of ...or growth hormone (GH), two key regulators of ...
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Leptin-deficient mice have altered three-dimensional growth plate histomorphometry
... purchased for the study (Jackson Laboratory; Bar Harbor, ME, USA). Ob/ob mice in this age range demonstrate obesity and hyperglycemia, as well as reduced thickness of the growth plate [10, 11]. All animals ...
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A Computed Microtomography Method for Understanding Epiphyseal Growth Plate Fusion
... study growth plate bridging in the context of a murine model of spontaneous osteo- arthritis (Staines et ...the growth plate which is very complex and cannot be captured correctly by 2D ...of ...
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On the State of Stress in the Growth Plate under Physiologic Compressive Loading
... longitudinal growth, such as Wolff’s law and Hueter-Volkmann law [5,6], ...the growth plate retards bone growth and conversely, reduced pressure or even accelerates its tension ...bone ...
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Computational modeling of the mechanical modulation of the growth plate by sustained loading
... the growth of the bone as a function of the proliferation and hypertrophy of chondrocytes in the growth ...MPa. Growth was simulated during 23 days, obtaining numerical errors between ...the ...
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Magnetic resonance imaging in the tibial epiphyseal growth plate development of Wistar rat
... eal plate appearances were evaluated qualitatively: the intensity variations were scored high, medium, or low based on comparison with muscle signal, which was assumed ...epiphyseal plate swell- ing was ...
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