Guanosine monophosphate
Nitric oxide generating vasodilators and 8 bromo cyclic guanosine monophosphate inhibit mitogenesis and proliferation of cultured rat vascular smooth muscle cells
... Nitric oxide-generating vasodilators and 8bromo-cyclic guanosine monophosphate inhibit mitogenesis and proliferation of cultured rat vascular smooth muscle cells.. Endothelium-derived re[r] ...
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Increased Plasma Cyclic Guanosine Monophosphate Concentrations in Children With High Levels of Circulating Atrial Natriuretic Peptide
... Simultaneous measurements of plasma atrial natriuretic peptide (ANP) and cyclic guanosine monophosphate (GMP) concentrations were performed in children with various forms of cardiac dise[r] ...
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Determinants of aortic cyclic guanosine monophosphate in hypertension induced by chronic inhibition of nitric oxide synthase
... Nitric oxide (NO) and atrial natriuretic factor (ANF) cause vascular relaxation by generating cyclic guanosine monophosphate (cGMP) via activation of the soluble and particulate guanylate cyclases, ...
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Role of cyclic adenosine monophosphate (cAMP) and cyclic guanosine monophosphate (cgmp) in oxidative metabolism, inflammation and cell death: case amphotericin b
... cyclic guanosine monophosphate (cGMP) signaling, S-nitrosylation of cysteine residues in target proteins constitutes another well-defined non-cGMP dependent mechanism of NO ...
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Increased cyclic guanosine monophosphate production and overexpression of atrial natriuretic peptide A receptor mRNA in spontaneously hypertensive rats
... Atrial natriuretic peptide (ANP) specifically stimulates particulate guanylate cyclase, and cyclic guanosine monophosphate (cGMP) has been recognized as its second messenger. Spontaneously hypertensive rats ...
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Effects of atrial natriuretic factor on cyclic guanosine monophosphate and cyclic adenosine monophosphate accumulation in microdissected nephron segments from rats
... We could not demonstrate an effect of ANF on cAMP accumulation in any of several preparations studied including: a microdissected rat proximal convoluted tubules in the presence or absen[r] ...
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Cyclic guanosine monophosphate as a mediator of vasodilation
... Nitric oxide ATP, NO derived from the nitrovasodilators, ETC and EDRF activate the soluble isoenzyme form of guanylate cyclase and result in increased cyclic GMP synthesis and cyclic GMP[r] ...
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Immunohistochemical studies of cyclic guanosine monophosphate and nuclear function
... A similar prominent increase in nucleolar size and cGMP staining was seen in the endometrial tissue of the uterus following estrogen administration to oophorectomized rats.. Thus, both i[r] ...
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QUANTUM ANALYSIS OF THE CYCLIC ADENOSINE MONOPHOSPHATE (AMPc) AND GUANOSINE MONOPHOSPHATE CYCLIC (GMPc) IN NEUROTRANSMITTERS
... That is, they will cause different damages and injuries to the brain, the spinal cord, the set of cranial and peripheral nerves, the nerve roots of the autonomic nervous system and the n[r] ...
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Guanylin stimulation of Cl secretion in human intestinal T84 cells via cyclic guanosine monophosphate
... Intestinal salt and fluid secretion is stimulated by Escherichia coli heat-stable enterotoxins ST through activation of a membrane guanylate cyclase found in the intestine.. Guanylin is [r] ...
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Migraine and cluster headache – the common link
... Glyceryl trinitrate (GTN), a prodrug of NO, was given intravenously (0.5 μg/kg/min for 20 min) in a double-blind, placebo controlled, cross over study on 12 MO patients [121]. At a median time of 5.5 h after GTN infusion ...
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A study of neuromodulation using the isolated locust (Schistocerca gregaria) first basalar motoneurone as an 'in vitro' model
... Since this time, a number o f protein kinases dependent on cAMP, cyclic guanosine monophosphate cGMP, diacylglycerol and Ca^+ for their activation, have been associated w ith the modulat[r] ...
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Phosphodiesterase 2A as a therapeutic target to restore cardiac neurotransmission during sympathetic hyperactivity
... phosphodiesterase 2A (PDE2A), which regulates the action of BNP-activated cyclic guanosine monophosphate (cGMP), was directly involved in modulating Ca 2+ handling from stellate ganglia[r] ...
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Sleep related painful erection: an algorithm for evaluation and management
... Phosphodiesterase type 5 (PDE5) inhibitors at low doses (sildenafil 25 mg daily or tadalafil 5 mg daily) were stud- ied successfully. PDE5 is responsible for the degradation of cyclic guanosine ...
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The STING ligand cGAMP potentiates the efficacy of vaccine-induced CD8+ T cells
... cyclic guanosine monophosphate-adenosine monophosphate (cGAMP), a ligand for the stimulator of interferon genes (STING), on the induction of antigen-specific CD8 + T ...
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Effects of elevated ecdysteroid on tissue expression of three guanylyl cyclases in the tropical land crab Gecarcinus lateralis: possible roles of neuropeptide signaling in the molting gland
... List of abbreviations 20-hydroxyecdysone 3⬘,5⬘-cyclic guanosine monophosphate crustacean hyperglycemic hormone ecdysone receptor ES ganglia eyestalk ES ablation guanylyl cyclase Gecarcin[r] ...
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Low serum insulin-like growth factor-1 in patients with erectile dysfunction
... cyclic guanosine monophosphate; ED: erectile dysfunction; eNOS: endothelial nitric oxide synthase; EPC: endothelial progenitor cell; FMD: flow mediated dilatation; HDL: high density lipoprotein cholesterol; ...
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Bixa orellana leaf extract suppresses histamine induced endothelial hyperpermeability via the PLC NO cGMP signaling cascade
... instance the activation of protein kinase C [6], the gener- ation of inositol trisphosphate and a rise in intracellular Ca 2+ [7]. In addition, histamine-stimulated endothelial hyperpermeability also involves the nitric ...
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NO/redox disequilibrium in the failing heart and cardiovascular system
... Analysis of several such examples 17–22 has shown that S-nitrosylation the covalent attachment of NO Nonstandard abbreviations used: cGMP, 3′,5′-cyclic guanosine monophosphate; E-C, exci[r] ...
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Molecular mechanisms of cell proliferation induced by low power laser irradiation
... cyclic guanosine monophosphate; COX-2: cyclooxygenase-2; DAG: dia- cylglycerol; EGF: epidermal growth factor; eIF4E: Eukary- otic initiation factor 4E; eNOS: Endothelial NO synthase; ERK: extracellular ...
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