H?/K+ ATPase
Dietary acidification enhances phosphorus digestibility but decreases H+/K+ ATPase expression in rainbow trout
... Most fish species, including rainbow trout, have only a limited ability (~10–80%) to digest P in fish meal (Cho and Bureau, 2001), whereas birds and mammals can digest nearly 100% of P in fish meal (Soares, Jr, 1995). ...
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IN SILICO LIGAND-BASED 2D PHARMACOPHORE GENERATION FOR H+/K+ ATPASE INHIBITORS
... Gastric H + /K + ATPase pump is located in the parietal cells 1 and plays a crucial role in the formation of ulcers in the ...stomach. H pylori transmission occurs in 50% of the people ...
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GASTROPROTECTIVE ACTIVITY OF MICHELIA NILAGIRICA IN RATS: POSSIBLE INVOLVEMENT OF H+-K+-ATPASE INHIBITION
... The preliminary phytochemical analysis of Michelia nilagirica showed the presence of alkaloids, annins, terpinoids, carbohydrates, flavanoids, proteins and aminoacids. The antiulcer property of Michelia nilagirica in ...
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Enzymatic Activity of Renal H K ATPase in the Outer Medullary Collecting Duct of Transgenic Mice
... The H-K-ATPase (HKA), a potassium-dependent proton transporter in the outer medullary col- lecting duct (OMCD) plays an important role in acid-base ...a K-free diet ...In K presence, ...
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THE H+/K+ ATPase INHIBITORY ACTIVITY OF ETHANOLIC EXTRACT OF DIOSPYROS PANICULATA Dalz BARK
... of H + , K + - ATPase in the presence of different concentrations (10–50 μl) of each sample ...with H + , K + -ATPase for 30 ...
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The gastric H,K-ATPase in stria vascularis contributes to pH regulation of cochlear endolymph but not to K secretion
... Strial K + flux is NOT carried by basolateral H + ,K + ATPase It was proposed that the basolateral H + ,K + -ATPase contributes to transepithelial K + secretion by ...
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Pithecellobium dulce Fruit Extract Exerts Antiulcerogenic effect by Influencing the Gastric expression of H+, K+-ATPase and Mucosal Glycoproteins
... is suggestive that the extract from P. dulce exerts a proton pump inhibitor like activity. In addition, it was observed that the expression of MUC6 and MUC2 genes in the gastric and duodenal mucosa of the P.dulce ...
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Inhibition of gastric H,K-ATPase activity and gastric epithelial cell IL-8 secretion by the pyrrolizine derivative ML 3000
... Gastric H,K-ATPase activity was dose-dependently inhib- ited by ML 3000, with a half-maximal inhibitory concen- tration (IC 50 ) of ...on H,K-ATPase activity under assay ...
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The Antioxidant and H+K+ ATPase Inhibitory Effect of Andrographis Paniculata and Andrographolide In Vitro and In Vivo Studies
... + K + ATPase is the proton pump responsible for gastric acid secretion 50, 51 , and the final common pathway mediating secretion of hydrochloric acid by gastric parietal cells 52 ...intracellular H + ...
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Analysis of the membrane domain of the gastric H(+)/K(+) ATPase
... protein h −1 are routinely ...gastric ATPase, namely around 100 µmol mg −1 h −1 ...of K m for NH 4 + , the cation used to obviate problems of ...
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Increased sensitivity to K+ deprivation in colonic H,K ATPase deficient mice
... for K 1 absorption in the col- lecting duct during K 1 deprivation (17–19, ...rat, K 1 depletion caused a sharp increase in cHKA mRNA in kidneys of cHKA 1/1 mice, consistent with the possibility that ...
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The vacuolar H(+) ATPase one of the most fundamental ion pumps in nature
... Recently, we observed that removal of the catalytic sector of eukaryotic V-ATPases from the membrane failed to generate increased proton conduction across the depleted membranes Beltran [r] ...
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Physiological adaptation of an Antarctic Na+/K+ ATPase to the cold
... Do transmembrane proteins undergo specific changes to better respond to the cold? This is likely, given molecular adaptation has been shown for soluble enzymes, particularly those involved in metabolic pathways or ...
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Biogenesis and function of the yeast plasma membrane H(+) ATPase
... DeWitt et al., 1998; Sen Gupta et al., 1998). The same mutants are exceedingly sensitive to low concentrations of trypsin, consistent with the idea that they are poorly folded and arrested by the endoplasmic reticulum ...
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Cytochemical localization of Na+, K+ ATPase in the rat hepatocyte
... localized to the luminal side of the membrane. These findings indicate that Na+,K+-ATPase is localized to the sinusoidal and lateral portions of the rat hepatocyte plasma membrane and is not detectable on ...
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Seawater acclimation causes independent alterations in Na+/K+ and H+ ATPase activity in isolated mitochondria rich cell subtypes of the rainbow trout gill
... demonstrated by ouabain-binding studies (McCormick, 1990), but can be considered relatively mitochondria-rich, at least when compared with surrounding PVCs (Laurent and Dunel, 1980). In our assay, the accessory cells ...
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Sperm Na+ K+-ATPase and Ca2+-ATPase Activities: A Potential Predictive Parameter of Sperm Motility Disorder in Infertile Men
... activity and its isoform in order to support and maintain membrane potential, motility changes, and hyperactivation during capacitation, all of which play a crucial role in male fertility. In addition, based on ...
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IMMUNOLOCALIZATION OF H+ ATPase IN THE GILL EPITHELIA OF RAINBOW TROUT
... The localization of the proton pump in fish gills is not known. It is possible that the pump is situated in the apical membranes, as in frog skin, turtle bladder and mammalian kidney. Experimentally, drugs and treatments ...
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Hypoxic responses of Na+/K+ ATPase in trout hepatocytes
... + ATPase whereas in CDNB-treated hepatocytes the latter was observed independent on oxygen ...+ ATPase in trout hepatocytes to oxidative stress, which does not occur in response to acute hypoxic insult, ...
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The role of the V ATPase in renal epithelial H+ transport
... In the cortical and outer medullary collecting tubule, proton secretion by the Atype intercalated cells varies with the proton electrochemical gradient across the apical plasma membrane,[r] ...
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