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Haemorrhagic shock

Effect of gelatin-polysuccinat on cerebral oxygenation and microcirculation in a porcine haemorrhagic shock model

Effect of gelatin-polysuccinat on cerebral oxygenation and microcirculation in a porcine haemorrhagic shock model

... of haemorrhagic shock before availability of extended interventions like transfusion of blood products or specific and goal-directed treatment of coagulation ...

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Protocol for a systematic review of the impact of resuscitation fluids on the microcirculation after haemorrhagic shock in animal models

Protocol for a systematic review of the impact of resuscitation fluids on the microcirculation after haemorrhagic shock in animal models

... following haemorrhagic shock are influenced by global haemodynamic parameters such as blood pressure and cardiac ...after haemorrhagic shock is ...following haemorrhagic shock ...

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Feasibility of optical coherence tomography angiography to assess changes in retinal microcirculation in ovine haemorrhagic shock

Feasibility of optical coherence tomography angiography to assess changes in retinal microcirculation in ovine haemorrhagic shock

... [35] presented preliminary results of OCT-A analyses during haemorrhagic shock in rats and reported a constant retinal blood flow despite a drop in MAP. Although exact values were not reported, it may be ...

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Skeletal muscle oxygenation in severe trauma patients during haemorrhagic shock resuscitation

Skeletal muscle oxygenation in severe trauma patients during haemorrhagic shock resuscitation

... by haemorrhagic shock ...septic shock [26,27] and was correlated with the patient outcome ...with haemorrhagic shock who showed no im- provement in SOFA score might have suffered an ...

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Performance of closed-loop resuscitation of haemorrhagic shock with fluid alone or in combination with norepinephrine: an experimental study

Performance of closed-loop resuscitation of haemorrhagic shock with fluid alone or in combination with norepinephrine: an experimental study

... This study explored extensively the performances of several algorithms for CL resuscitation of haemor- rhagic shock with fluid alone and with co-administra- tion of fluid and norepinephrine. The performance of the ...

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Comparison of an automatic analysis and a manual analysis of conjunctival microcirculation in a sheep model of haemorrhagic shock

Comparison of an automatic analysis and a manual analysis of conjunctival microcirculation in a sheep model of haemorrhagic shock

... analyses using high-quality conjunctival videos. It may be possible that automatic ana- lysis works better with sublingual videos of microcirculation. Also, the AVA software version 4.2 was developed to automatically ...

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Retrospective study of the effectiveness of Intra-Aortic Balloon Occlusion (IABO) for traumatic haemorrhagic shock

Retrospective study of the effectiveness of Intra-Aortic Balloon Occlusion (IABO) for traumatic haemorrhagic shock

... in shock on arrival (systolic blood pressure [SBP] <90 mmHg or shock index ≥ 1), underwent IABO for resuscitation and temporary haemostasis, and subsequently underwent haemostatic intervention (operation ...

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Pre-hospital plasma in haemorrhagic shock management: current opinion and meta-analysis of randomized trials

Pre-hospital plasma in haemorrhagic shock management: current opinion and meta-analysis of randomized trials

... Background: Trauma-induced coagulopathy is one of the most difficult issues to manage in severely injured patients. The plasma efficacy in treating haemorrhagic-shocked patients is well known. The debated issue is ...

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Resuscitation of haemorrhagic shock with normal saline vs  lactated Ringer's: effects on oxygenation, extravascular lung water and haemodynamics

Resuscitation of haemorrhagic shock with normal saline vs lactated Ringer's: effects on oxygenation, extravascular lung water and haemodynamics

... Introduction Pulmonary oedema and impairment of oxygenation are reported as common consequences of haemorrhagic shock and resuscitation (HSR). Surprisingly, there is little information in the literature ...

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Timely completion of multiple life-saving interventions for traumatic haemorrhagic shock: a retrospective cohort study

Timely completion of multiple life-saving interventions for traumatic haemorrhagic shock: a retrospective cohort study

... may be appropriate while the circulation is prioritised, provided the airway is patent [40]. As such, this manu- script focused on LSIs that would be considered mandatory, rather than debatable during resuscitation of ...

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Haemodynamic and renal effects of resuscitation of dogs from haemorrhagic shock with hypertonic saline or Lactated Ringer's solution combined with whole blood

Haemodynamic and renal effects of resuscitation of dogs from haemorrhagic shock with hypertonic saline or Lactated Ringer's solution combined with whole blood

... Urinary output and glomerular filtration rate are reduced during haemorrhagic shock. Urinary out- put was restored to normal (Walsh and Kramer, 1991), or to at least three times the baseline level (Nakayama ...

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Effects of fresh frozen plasma, Ringer’s acetate and albumin on plasma volume and on circulating glycocalyx components following haemorrhagic shock in rats

Effects of fresh frozen plasma, Ringer’s acetate and albumin on plasma volume and on circulating glycocalyx components following haemorrhagic shock in rats

... Background: Early use of fresh frozen plasma (FFP) in haemorrhagic shock is associated with improved outcome. This effect may partly be due to protection of the endothelial glycocalyx and/or secondary to a ...

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Fluid resuscitation in haemorrhagic shock in combat casualties

Fluid resuscitation in haemorrhagic shock in combat casualties

... aliquots of 500 ml each to supplement fluid resuscitation in trauma patients is safe and does not result in a coagu- lopathy [11–13]. However, the FDA issued a safety com- munication on HESs (Hespan, Hextend, and ...

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Mullerian Anomalies Manifesting as Haemorrhagic Shock: A Series of Rare Cases

Mullerian Anomalies Manifesting as Haemorrhagic Shock: A Series of Rare Cases

... in haemorrhagic shock and diagnosed as cases of mullerian anomalies not known ...study. Shock is graded as per ...of haemorrhagic shock regarding presence of mullerian ...

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Effects of terlipressin as early treatment for protection of brain in a model of haemorrhagic shock

Effects of terlipressin as early treatment for protection of brain in a model of haemorrhagic shock

... regard to the brain region analysed. Third, cerebral blood flow was not measured, because the purpose of the present study was to evaluate changes in CPP and oxygenation. Also, the anaesthetics used may be ...

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Fluid sparing and norepinephrine use in a rat model of resuscitated haemorrhagic shock: end-organ impact

Fluid sparing and norepinephrine use in a rat model of resuscitated haemorrhagic shock: end-organ impact

... The major differential effect of the two resuscitation strategies, as well as the more congruent findings, was in the brain. To note that in our model, the amygdala was used as a sensitive zone of the brain but does not ...

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Compared effects of inhibition and exogenous administration of hydrogen sulphide in ischaemia reperfusion injury

Compared effects of inhibition and exogenous administration of hydrogen sulphide in ischaemia reperfusion injury

... PE induced a dose-dependent increase in tension in aortic and small mesenteric vessels in control rats. In contrast, haemorrhagic shock blunted PE-stimulated contraction (P <0.01), whereas NaHS ...

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Resuscitation strategies with different arterial pressure targets after surgical management of traumatic shock

Resuscitation strategies with different arterial pressure targets after surgical management of traumatic shock

... uncontrolled haemorrhagic shock rat model, induced by the transection of the splenic paren- chyma and one of the branches of the splenic artery ...with haemorrhagic shock, as compared with ...

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Is the shock index based classification of hypovolemic shock applicable in multiple injured patients with severe traumatic brain injury?—an analysis of the TraumaRegister DGU®

Is the shock index based classification of hypovolemic shock applicable in multiple injured patients with severe traumatic brain injury?—an analysis of the TraumaRegister DGU®

... and haemorrhagic shock, the rise of SI was markedly attenuated in non surviving animals which suggests a lack of car- diovascular response to haemorrhage ...one shock class the presence of severe TBI ...

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Microcirculatory perfusion shows wide inter-individual variation and is important in determining shock reversal during resuscitation in a porcine experimental model of complex traumatic hemorrhagic shock

Microcirculatory perfusion shows wide inter-individual variation and is important in determining shock reversal during resuscitation in a porcine experimental model of complex traumatic hemorrhagic shock

... Our study was opportunistic in nature and although we prospectively collected data, we not unsurprisingly ended up with groups of animals which had received a variety of heterogeneous injuries and treatments. We did ...

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