hairy cell leukemia
Hairy cell leukemia: A retrospective study on 11 patients in the Western of Iran.
... Hairy cell leukemia (HCL) is a chronic B-cell lymphoid leukemia characterized by pancytopenia, splenomegaly, myelofibrosis and the presence in peripheral blood, bone marrow and spleen ...
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Autoimmune conditions and hairy cell leukemia: an exploratory case-control study
... syndrome, and erythema nodosum although strong (ORs 9.6, 6.1 and 37, respectively) were based on few affected HCL cases and may have occurred by chance. Given the rarity of HCL, our study is the largest to date. Our ...
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www.ijcep.com /IJCEP710001 Case Report Hairy Cell Leukemia with Unusual Loss of CD103 in a Subset of the Neoplastic Population: Immunophenotypic and Cell Cycle Analysis by Flow Cytometry
... Figure 3 DNA cell cycle analysis. In order to determine if differences in tumor proliferation were present between the CD103+ and CD103- tumor cells, simultaneous single tube DNA analysis was performed using ...
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High levels of circulating soluble receptors for tumor necrosis factor in hairy cell leukemia and type B chronic lymphocytic leukemia
... immunoassays using nonblocking anti-receptor antibodies and 125I-recombinant human TNF alpha. As compared to the titers observed in 25 healthy controls, TNFBP types A and B titers were found to be elevated in almost all ...
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TGF β1 induces bone marrow reticulin fibrosis in hairy cell leukemia
... Hairy cell leukemia (HCL) is a chronic lymphoproliferative disorder characterized by the presence of hairy cells (HCs) in peripheral blood, bone marrow (BM), and spleen and is invariably ...
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Hairy cell leukemia – immunotargets and therapies
... Abstract: Hairy cell leukemia (HCL) is an indolent low-grade B-cell lymphoproliferative disorder that is reasonably sensitive to standard first-line purine analog ...
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Types of second primary cancers influence survival in chronic lymphocytic and hairy cell leukemia patients.
... Types of second primary cancers influence survival in chronic lymphocytic and 53. hairy cell leukemia patients 64[r] ...
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Hairy cell leukemia in kidney transplantation: lesson from a rare disorder
... [5-7]. Hairy cell leukemia (HCL) is a rare indolent B-cell lymphopro- liferative disease that induces severe, life-threatening pan- cytopenia and is not currently considered a ...
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Interleukin 6 functions as an intracellular growth factor in hairy cell leukemia in vitro
... B cell derived hairy cell leukemia (HCL) was ...Purified hairy cells (HCs) did not increase DNA synthesis in vitro in response to exogenous IL-6; however, they expressed IL-6 receptor ...
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<p><em>BRAF</em> V600E-positive monomorphic epitheliotropic intestinal T-cell lymphoma complicating the course of hairy cell leukemia</p>
... Hairy cell leukemia (HCL) is an uncommon B-cell chronic lymphoproliferative disorder whose pathogenesis and recurrence are strictly dependent on the presence of the BRAF V600E mutant, a ...
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Current and emerging treatment options for hairy cell leukemia
... Abstract: Hairy cell leukemia (HCL) is a lymphoproliferative B-cell disorder characterized by pancytopenia, splenomegaly, and characteristic cytoplasmic hairy ...
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Neutropenia caused by hairy cell leukemia in a patient with myelofibrosis secondary to polycythemia vera: a case report
... this cell population was hairy cell leukemia cells ...2012, hairy cells were found in ...stem cell transplant, but owing to high risk for recurrence after transplant, it was ...
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Hairy Cell Leukemia: Review
... The accumulation of abnormal B-lymphocytes which is an uncommon hematological malignancy is called ‘Hairy cell leukemia’ because of its hairy appearance under microscope. These malignant cells ...
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Original Article Immunohistochemical analysis using a BRAF V600E mutation specific antibody is highly sensitive and specific for the diagnosis of hairy cell leukemia
... Hairy cell leukemia (HCL) is a mature B-cell malignancy characterized by splenomegaly, pancytopenia, and circulating lymphoid cells with circumferential “hairy” cytoplasmic projec- ...
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www.ijcep.com /IJCEP1012010 Case Report Hairy cell leukemia and variant in Taiwan: report of a variant case and literature review
... Abstract: Hairy cell leukemia (HCL) is characterized by leukemic cells with abundant “hairy” cytoplasm, strong cyto- plasmic positivity for tartrate-resistant acid phosphatase (TRAP), ...
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Monoclonal antibodies with specificity for hairy cell leukemia cells
... Hairy cell leukemia is a well described clinical entity, but the cell of origin for this leukemic cell and its function are still ...this cell, although tartrate-resistant acid ...
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www.ijcep.com /IJCEP1008005 Case Report CD20dim-positive T-cell large granular lymphocytic leuke- mia in a patient with concurrent hairy cell leukemia and plasma cell myeloma
... lived plasma cells. In a study of secondary can- cer incidence from a cohort of 3104 patients with hairy cell leukemia with a mean follow-up 6.5 years [24], non-Hodgkin and Hodgkin lym- phoma were ...
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Case Report A case study of t(14;22)(q32;q11) involving immunoglobulin heavy and light chain in follicular lymphoma
... lymphocytic leukemia (CLL)/small lymphocytic lymphoma (SLL), 1 case of hairy cell leukemia (HCL), 1 case of HCL variant (HCL-v), 1 case of diffuse large B cell lymphoma (DLBCL), and 1 ...
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Sex chromosome loss and the pseudoautosomal region genes in hematological malignancies
... stem/progenitor cell, it also stimulates proliferation of myeloid cells and is often used as a growth factor for myeloid cell lines ...lymphoma, hairy cell leukemia, systemic ...
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“Hairiness” is a Facsimile of Reorganized Cytoskeletons: A Cytopathic Effect of Coxiella burnetii
... into hairy cells (cbHCs), the first hairy cell reported outside of hairy cell leukemia ...and hairy cells in HCL are distinct among lymphoid cells in ...maintaining ...
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