Han population
The Association of SERPINE2 Gene with COPD in a Chinese Han Population
... Chinese Han population. Samples were collected from a Chi- nese Han population and analyzed for the association of single nucleotide polymor phisms (SNPs) or haplotypes of SERPINE2 gene with ...
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Genetic variants in TERT are associated with risk of gastric cancer in a Chinese Han population
... Telomerase reverse transcriptase (TERT) is a gene within the cancer susceptibility region located at Chr5p15.33, which is associated with multiple cancer types. In this study, we validated the association between TERT ...
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Association of C5aR1genetic polymorphisms with coronary artery disease in a Han population in Xinjiang, China
... For genes with multiple susceptibilities, an analysis based on haplotypes has advantages over an analysis based on individual SNPs, particularly when the linkage disequilibria between the SNPs is weak [47]. Our study is ...
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Original Article Lack of an independent relationship between CXCL16 gene rs2277680 polymorphism and instability of carotid plaque in the Chinese Han population
... After cleavage by a metalloproteinase (ADAM- 10), membrane-bound CXCL16 is released extracellularly in a soluble form [12] that causes inflammatory cells to aggregate and infiltrate the lesion, promotes angiogenesis and ...
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A single nucleotide polymorphism rs708567 in the IL 17RC gene is associated with a susceptibility to and the curve severity of adolescent idiopathic scoliosis in a Chinese Han population: a case control study
... Overall, we found a positive association between SNP rs708567 and the susceptibility to and curve severity of AIS in a Chinese Han population. Unfortunately, the specific influence of SNP rs708567 on ...
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Original Article IL1R2 polymorphisms and knee OA susceptibility in a Chinese Han population
... Abstract: Interleukin 1 (IL-1) is one of the most pivotal proinflammatory cytokines in the pathogenesis of osteoar- thritis (OA) and its decoy receptor, IL-1R2, has also been demonstrated might involve in the development ...
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Original Article No association of VAMP8 gene polymorphisms with glioma in a Chinese Han population
... Abstract: Vesicle-associated membrane protein 8 (VAMP8) gene plays an important role in biological functions like endosomal fusion, sequential granule-to-granule fusion and autophagy. The current research identified VAMP8 ...
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Idiopathic male infertility in the Han population in China is affected by polymorphism in the VDAC2 gene
... The mean age of the 523 males in the Han population in this study who could not have babies was 32.0 ± 5.6 years of age (range 20–55 years). The time between experimentation and semen collection was 5.0 ± ...
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Association of inflammatory gene polymorphisms with ischemic stroke in a Chinese Han population
... Results: We found two single nucleotide polymorphisms (SNPs) in CCL11 were associated with ischemic stroke. After adjusting for multiple testing using false discovery rate (FDR) with a 0.20 cut-off point, CCL11 rs4795895 ...
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Association analysis of ANK3 gene variants with schizophrenia in a northern Chinese Han population
... Chinese Han population of 499 schizophrenia patients and 500 controls to investigate the effect of variant genotypes of 13 SNPs in ANK3 on schizophrenia ...
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Genetic variants in the ZNF208 gene are associated with esophageal cancer in a Chinese Han population
... Previous studies showed an association between the ZNF208 gene and gastric cancer. In this study, we investigated the association between single nucleotide polymorphisms (SNPs) in ZNF208 and the risk of esophageal cancer ...
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Polymorphisms of PRLHR and HSPA12A and risk of gastric and colorectal cancer in the Chinese Han population
... We recruited 588 patients with gastric cancer and 449 with colorectal cancer between December 2010 and November 2014 from the Department of General Surgery, the Second Affiliated Hospital, Xi’an Jiaotong University ...
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KCNQ1 gene polymorphisms are associated with lipid parameters in a Chinese Han population
... Our novel findings that the risk alleles of rs2283228 and rs2237892 within the KCNQ1 gene are associated with levels of TG, HDL-C and apo A1 in a middle-aged Chi- nese Han population are encouraging. Though ...
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The haplotype of UBE2L3 gene is associated with Hashimoto’s thyroiditis in a Chinese Han population
... Genetic variation in the UBE2L3 has been demon- strated in many autoimmune diseases such as systemic lupus erythematosus (SLE) [13–15], rheumatoid arthritis (RA) [15, 16] and Crohn’s disease (CD) [17, 18]. As we all ...
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RTEL1 polymorphisms are associated with lung cancer risk in the Chinese Han population
... In our case-control study, we evaluated seven SNPs associated with LC susceptibility in a Chinese Han population and our found that rs2738780 and the ‘‘CTC’’ haplotype are associated with decreased LC risk. ...
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Prevalence of CYP17A1 gene mutations in 17α-hydroxylase deficiency in the Chinese Han population
... hypertension, hypokalemia, male pseudohermaphroditism and female gonadal dysplasia. The diagnosis of 17α-OHD is based on a comprehensive overview of clinical, biochem- ical and molecular features. However, the clinical ...
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Association of NCOA3 polymorphisms with Dyslipidemia in the Chinese Han population
... Chinese Han subjects were randomly selected from individuals who received routine health examina- tions at the General Hospital of Jilin Chemical Group Corporation between September 2009 and June ...
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Optimal cutoff of the triglyceride to high-density lipoprotein cholesterol ratio to detect cardiovascular risk factors among Han adults in Xinjiang
... among Han adults in Xinjiang are ...Xinjiang Han adults compared with Guangdong, Zhuhai, and Ghanaian. The Han population in Xinjiang consumes more meat, milk products, salt, and pasta than ...
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RTEL1 tagging SNPs and haplotypes were associated with glioma development
... Albeit the correlated survival data in the present study are still accumulating, our findings in this study have provided new evidence for the association between com- mon SNPs (or haplotypes) and the risk of glioma in ...
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Association of multiple genetic variants with breast cancer susceptibility in the Han Chinese population
... We selected 13 tag single nucleotide polymorphisms (tSNPs) to investigate whether they were associated with breast cancer risk in the Chinese Han population. Upon statistical analyses of clinical data from ...
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