HAP and LPS induced TNF-α secretion
Eukaryotic elongation factor 2 controls TNF α translation in LPS induced hepatitis
... regulating TNF-a expression is through the control of protein elongation during translation, which would allow rapid cell adaptation to physiological ...nascent TNF-a protein in ...subsequent TNF-a ...
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Inhibition of p38MAPK and CD137 signaling reduce dengue virus induced TNF α secretion and apoptosis
... reduce TNF-α ...Biotechnology). TNF-α mRNA expression of DENV- infected HepG2 cells and TNF-α protein expression in supernatant of DENV-infected HepG2 cells were subse- quently ...
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Dimethylfumarate protects against TNF-α-induced secretion of inflammatory cytokines in human endothelial cells
... Dimethylfumarate (DMF) has been successfully used in the treatment of psoriasis, a chronic inflammatory disease, for more than 40 years [5], and several clinical trials have proven its efficacy. Last year, DMF was ...
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Modulation of Anti-Tumor Necrosis Factor Alpha (TNF-α) Antibody Secretion in Mice Immunized with TNF-α Kinoid
... antibodies induced by TNF-K immunization were not significantly influenced by a concomitant low-dose immunosuppressive treatment, such as methylprednisolone or ...to TNF-K. We observed a slight ...
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Ashwagandha attenuates TNF α and LPS induced NF κB activation and CCL2 and CCL5 gene expression in NRK 52E cells
... of TNF-α to induce CCL5 expression; published studies have shown that NRK-52E cells re- spond to 10 ng/ml for 6–48 h [43, ...h induced an approximate 10-fold increase in CCL5 gene expression that was ...
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LPS Induced Proliferation and Chemokine Secretion from BEAS 2B Cells
... chemokine secretion of BEAS-2B cells, a human bronchial epithelial cell line, after LPS stimulation, and some details of involved ...on LPS with increased proliferation, activation of NFκB, and the ...
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The effect of zinc supplementation on pro-inflammatory cytokines (TNF-α, IL-1 AND IL-6) in mice with Escherichia coli LPS-induced diarrhea
... of TNF which can cause systemic reactions ...as TNF-α and IL-1β by monocytes and macrophages which were activated by the inflammatory process and were as- sociated with decreased zinc status in ...in ...
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Extracellular caspase 6 drives murine inflammatory pain via microglial TNF α secretion
... the C-fiber marker TRPV1, because CASP6 immunostaining was eliminated completely by the TRPV1 agonist RTX. Further, spi- nal CASP6 is upregulated in CSF after acute inflammation. Thus, it is conceivable that CASP6 ...
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CiteSeerX — Soluble TNF, but not mem in LPS-induce
... This TNF-driven response is absolutely required for protection against mycobacte- ria, although the high dose of TNF also causes considerable liver tissue ...while TNF plays an essential role in ...
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The Effect of Methanol Extract of Echinops Lasiolepis on TNF-α Production in LPS-activated J774 A.1 Mouse Macrophages
... mononuclear cells and interferon gamma (INF-γ) secretion were investigated. The study results showed that most concentrations of Echinops lasiolepis extract produced inhibitory effect on peripheral blood ...
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CiteSeerX — Taurine blunts LPS-induced increases in intracellular calcium and TNF� production by Kupffer cells
... ACKNOWLEDGMENTS The authors want to thank Mrs. Julie Vorobiov in the Center for Gastrointestinal Biology and Disease, University of North Carolina at Chapel Hill (supported by NIH Grant P30DK34987) for assistance with ...
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Chloroquine Interferes with Lipopolysaccharide-Induced TNF- Expression by a Nonlysosomotropic α Gene Mechanism
... with TNF- ␣ release from mononu- clear ...of LPS-induced TNF- ␣ release from human PBMC at therapeutically attainable ...release, secretion of RANTES was unaffected. CQ acted by ...
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Unaltered TNF-α production by macrophages and monocytes in diet-induced obesity in the rat
... factor- α (TNF- α ), in response to bacteria and bacterial fragments, such as LPS, monocytes and macrophages are essential to the first line of defence at contact sites between the interior ...
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Norepinephrine enhances the LPS-induced expression of COX-2 and secretion of PGE2 in primary rat microglia
... in LPS-stimulated microglia [37], and it has been demonstrated that NE increases the activity of mitogen-activated protein kinases (MAPK) [38] as well as transcription factors ...of TNF a , IL-12 and NO in ...
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miR-135b-5p inhibits LPS-induced TNF aproduction via silencing AMPK phosphatase Ppm1e
... (LPS)- induced tissue-damaging TNFa ...Further, LPS-induced TNFα production in above cells was dramatically ...by LPS. AMPK activation is required for miR-135b-induced actions in ...
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TNF-α and neuropathic pain - a review
... the TNF ligand and the TNF receptor (both belonging to the TNF/TNFR SPF), the transmembrane portion of TNF molecule (mTNF), besides being a ligand, is capable of acting as a receptor for a ...
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A Novel TNF-α-Targeting Aptamer for TNF-α-Mediated Acute Lung Injury and Acute Liver Failure
... SIRS is a common phenomenon upon end-organ damages [1, 3, 13]. Cytokine storms that follow organ damages can reshape a single organ disease into a systemic inflammatory disorder that eventually leads to multiple organ ...
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TNF-Signaling Modulates Neutrophil-Mediated Immunity at the Feto-Maternal Interface During LPS-Induced Intrauterine Inflammation.
... genes induced by LPS involved in inflammatory signaling and innate immunity in chorio-decidua ...data, TNF-blockade decreased LPS-induced neutrophil accumulation and activation at the ...
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Brucella abortus induces TNF-α-dependent astroglial MMP-9 secretion through mitogen-activated protein kinases
... the secretion of MMP-9 was ex- amined. PMA was used as control. The secretion of MMP-9 was markedly enhanced in culture supernatants from astrocytes stimulated with HKBA when compared with the unstimulated ...
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Glycyrrhiza uralensis flavonoids inhibit brain microglial cell TNF-α secretion, p-IκB expression, and increase brain-derived neurotropic factor (BDNF) secretion
... of TNF-a and other inflammatory cytokine production in the ...inhibited TNF-a production by ...of TNF-a by LPS stimulated BV-2 mouse microglial cells in a dose- dependent ...of TNF-a ...
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