HBeAg-Negative
Long term outcomes after nucleos(t)ide analogues discontinuation in chronic hepatitis B patients with HBeAg negative
... For HBeAg-negative CHB patients, relapse is frequent even when HBV DNA levels have been suppressed to undetectable for more than one year, making the precise endpoint for NUCs withdrawal ...
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HBV DNA level could predict significant liver fibrosis in HBeAg negative chronic hepatitis B patients with biopsy indication
... in HBeAg-negative CHB patients with varying ALT with an OR of ...in HBeAg-negative CHB patients with normal ALT and varying ages in Xiao et ...in HBeAg-positive CHB patients ...naïve ...
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Treatment of HBeAg Negative Chronic Hepatitis B Patients with Nucleos(t)ide Analogues in Burkina Faso
... In HBeAg-negative patients with DNA superior than 2000 UI/ml and ALT higher twice than the ULN, treatment is indicated even without evaluation of fi- brosis, because it will bring only useful additional ...
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Serum hyaluronate as a non-invasive marker of hepatic fibrosis and inflammation in HBeAg-negative chronic hepatitis B
... In this study we have shown that::1) Sub groups of patients with HBeAg negative chronic hepatitis B who had extensive fibrosis and inflammation had also high serum hyaluronate level. The differences were ...
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High Frequency of HBeAg Negative Cases in Naive HBsAg Positive Subjects with Chronic Hepatitis B Virus Infection Managed in the Yaoundé Hepatitis Therapeutic Committee: A Cross Sectional Study
... the HBeAg-negative patients were older, mostly male, mostly had normal serum ALT levels and low serum HBV DNA concentrations compared to those with positive ...positive HBeAg pa- tients, unlike in ...
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Positive association between serum apolipoprotein M levels and hepatitis B virus DNA load in HBeAg-negative chronic hepatitis B
... in HBeAg-negative, but not HBeAg-positive, CHB ...in HBeAg-negative ...that HBeAg may play a role in apoM-related lipid metabolism and ...
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Serum apolipoprotein C3 levels are negatively associated with hepatitis B virus DNA in HBeAg-negative chronic hepatitis B patients
... infection is reported to be a major cause of chronic liver disease [17], which indicates the close relationship be- tween HBV and lipid metabolism. In our study, we ex- amined the serum levels of ALT, AST, TBI, DBI, ...
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Original Article Association between serum levels of hepatitis B e-antigen and severity of liver fibrosis
... were HBeAg-positive (HBeAg(+)) and 86 (35%) were HBeAg-negative ...in HBeAg(+) patients were significantly higher than in HBeAg(-) ...HBsAg, HBeAg, and HBV DNA were ...
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The hepatitis B virus core and e antigens elicit different Th cell subsets: antigen structure can affect Th cell phenotype.
... secreted HBeAg is not required for replication or infection (5, ...for HBeAg in the viral life cycle has been ...that HBeAg can modulate the complex interaction be- tween HBV and the immune system ...
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Immune Tolerance Split between Hepatitis B Virus Precore and Core Proteins
... an HBeAg-negative mutant virus often results in acute fulminant rather than chronic HBV infection (7, ...an HBeAg-negative mutant is often associated with a fulminant course of infection ...
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Associations between HBeAg Status, HBV DNA, ALT Level and Liver Histopathology in Patients with Chronic Hepatitis B
... with HBeAg negative CHB infection, 10 ...of HBeAg negative CHB patients had HBV DNA levels ≤ 2000 IU/mL and normal serum ALT ...of HBeAg negative CHB patients had inflammatory ...
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Entecavir add-on or switch-to pegylated interferon improves HBsAg clearance in HBe antigen negative chronic hepatitis B patients
... patients (n=101) treated with ETV for ≥24 weeks in the Department of Infectious Diseases, Shanghai Rui Jin Hospital, The Fifth People’s Hospital of Suzhou, and Huai-An Fourth People’s Hospital from January 2012 to ...
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Original Article Hepatitis B virus e antigen (HBeAg) may have a negative effect on dendrtic cells maturation
... Although HBeAg is not necessary for infection or replica- tion of HBV [3], it is believed to be required for the establishment of chronic infection and probably responsible for the immunomodula- tion of host ...
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Predictive model for inflammation grades of chronic hepatitis B: Large‐scale analysis of clinical parameters and gene expressions
... HBV DNA level could predict significant liver fibrosis in HBeAg negative chronic hepatitis B patients with biopsy indication.. Newton RH, Leverrier S, Srikanth S, et al.[r] ...
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Relation between biochemical, serological, histological and viral replication indices in asymptomatic HBsAg positive individuals
... and HBeAg positivity) have been associated with an increased risk of transmission by needle stick exposure and by vertical ...to HBeAg-positive mothers who have high levels of viral replication (HBV DNA ...
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Telbivudine can safely reduce mother to child transmission in chronic hepatitis B women after 12 weeks of gestation
... and HBeAg levels and higher HBV DNA negative conversion rates compared to those in the lamivudine group before deliv- ery [16, ...in HBeAg positive or negative CHB mothers (rare of the studies ...
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Replicative and Transcriptional Activities of Hepatitis B Virus in Patients Coinfected with Hepatitis B and Hepatitis Delta Viruses
... different HBV genomic regulatory regions (14, 26). However, the molecular mechanisms possibly implicated in the discrep- ancy between pgRNA and pre-S/S RNA steady-state levels are unknown, and one cannot exclude that the ...
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Distinct patterns of serum hepatitis B core-related antigen during the natural history of chronic hepatitis B
... i.e., HBeAg-positive chronic infection, HBeAg-positive chronic hepatitis, HBeAg-negative chronic infection and HBeAg-negative chronic ...
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Hepatitis B Precore Protein: Pathogenic Potential and Therapeutic Promise
... to HBeAg positive CHB (immune ...of HBeAg status in fact reports on HBeAg ‘in excess’ in the serum, and actually HBeAg or anti-HBe negative status may not be absolute, but rather in an ...
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Virological profile of hepatitis B infection in Black African HBsAg chronic carriers
... Most of our patients were asymptomatic; the diagnosis was made on the occasion of blood donationor medical check-up (73.3% of the cases) and on the occasion of screening in subjects contacts of infected patients (12% of ...
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