HCT-15
Gallic acid induced apoptotic events in HCT-15 colon cancer cells
... Although apoptosis is confirmed by Yo-Pro-1 staining it would be more interesting to study the various pro-apoptotic and anti-apoptotic protein level in GA treated HCT-15 cells. The analysis of cyclin/ CDK, ...
11
Blocking heme oxygenase-1 by zinc protoporphyrin reduces tumor hypoxia-mediated VEGF release and inhibits tumor angiogenesis as a potential therapeutic agent against colorectal cancer
... Tumor hypoxia often derived from tumor-lodging micro- environment in many solid tumors which receive limited amounts of oxygen supply promptly promotes the forma- tion of new blood vessels. The advanced tumors exhibit ...
10
Synthesis and Cytotoxic Studies of Undecenoic Acid-based Schiffs Base Derivatives Bearing 1,2,4-Triazole Moiety
... line), HCT-15 (human colon cancer cells), SKOV3 (human ovarian cancer cell line) and a normal cell line NIH-3T3 (mouse embryonic fibroblasts) using MTT ...to HCT-15 cells ...
10
Usnea filipendula Induces Apoptosis in Human Colon Cancer Cell Lines
... µg/ml. HCT-15 and HT-29 cell lines were cultured in Roswell Park Memorial Institute (RPMI) medium 1640 (Lonza Bioscience, Verviers, Belgium) supplemented with penicillin G (100 U/ml), streptomycin (100 ...
8
Probiotic Screening of Lactobacilli Isolates from Uttapam Batter Fermented Supplementing with Piper betle L Leaves
... The in vitro screening of lactobacilli isolates from uttapam batter, fermented supplementing with Piper betle L. leaves, was performed in order to select potent isolates for probiotic use. Their re- sistance to simulated ...
13
MicroRNA-5p and -3p co-expression and cross-targeting in colon cancer cells
... change) ≥ 1.5 or ≤ −1.5, were extracted from the dataset of the 128 dysregulated miRNAs. A total of 19 pairs (38 miRNAs) that answered to this criterion were obtained (Table 1). The alterations observed in the cancer ...
14
Expression analysis and clinical significance of eIF4E, VEGF-C, E-cadherin and MMP-2 in colorectal adenocarcinoma
... To forward invasion and metastasis, the tumor cells initially break through the limitation of cell adhesions. The degradation of basement membranes and stromal extracellular matrix (ECM) plays a critical role in the ...
13
Sulfonamide derivative targeting carbonic anhydrase IX as a nuclear imaging probe for colorectal cancer detection in vivo
... cancer HCT-15 ...in HCT-15-induced xenograft mice possessed higher hypoxic fluorescence signal as compared with other ...in HCT-15-induced xenograft mice, was markedly enhanced ...
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Anticancer and Cytotoxic Potential of Aqueous Extract of Triticum aestivum on Colorectal Carcinoma
... The human colon cancer cell line (HCT- 15) & Vero (normal kidney cells) was provided by National Centre for Cell Science (NCCS), Pune. Stock cells of these cell lines were cultured in DMEM (high ...
6
Portuguese propolis disturbs glycolytic metabolism of human colorectal cancer in vitro
... Since AH.FC.09 and AH.FEr.09 were the most effect- ive fractions, we further assessed its effects on cell prolif- eration, metabolism and death. The results show that propolis led to a decrease in HCT-15 ...
8
Original Article Deep sequencing identifies deregulation of microRNAs involved with vincristine drug-resistan ce of colon cancer cells
... with HCT-8 covering an aver- age proportion of matches of ...of HCT-8/VCR amounted to ...of HCT-8 cells accounted for 41.4% of the total RNA, while the rRNA of HCT-8/VCR accounted for 47% of ...
7
CUL4A promotes proliferation and metastasis of colorectal cancer cells by regulating H3K4 trimethylation in epithelial–mesenchymal transition
... In this study, we provide evidence that CUL4A was overexpressed in primary CRC and cell line HCT-116 and predicted poor overall patient survival. Moreover, CUL4A promoted cell proliferation, colony formation, and ...
9
Survival adaptation in Everest: metabolic response during acclimatization in lowlander and sherpa climbers
... The energy was obtained from rechargeable batteries with a gasoline generator. The technique developed for monitoring of elite athletes was used: samples of capil- lary blood (finger) were drawn in BC in the morning in a ...
7
Neonatal Polycythemia: II. Definition Related to Time of Sampling
... We have recently shown that during the first 6 hours of life there is a significant and rapid change in the Hct and blood viscosity.7 Both the Hct and blood viscosity reach their peak at[r] ...
5
Denosumab treatment is associated with the absence of circulating tumor cells in patients with breast cancer
... Seventy-three consecutive patients with invasive breast cancer, progressive disease, high tumor load, treatment discontinuation at the time of CTC isolation (before the next line of therapy) and no preselection for ...
11
<p>LncRNA PTTG3P Sponge Absorbs microRNA-155-5P to Promote Metastasis of Colorectal Cancer</p>
... lines HCT-8 and HCT-116; (B) Transwell invasion was performed to detect the migration ability of HCT-8 after transfection of PTTG3P knockdown vector (Magni fi cation: 40 ×); (C) Cell scratch test was ...
9
Resistin and Visfatin Expression in HCT-116 Colorectal Cancer Cell Line
... A previous study has compared resistin protein expression in cancers with paired normal tissue using ELISA and western blot methods and reported an upregulation of resistin in CRC tissues. Immunohistochemistry analysis ...
8
High-dose immunosuppressive therapy and autologous HCT for relapsing-remitting MS
... Brain MRI was performed at screening post-MSRP, baseline, 12 months, 16 months, and then annually to 15 years, on scanners with 1.5T field strength. Scans were analyzed centrally (NeuroRx, Montreal, Canada). The ...
12
AN OVERVIEW OF THERAPEUTIC POTENTIAL OF THYMOQUINONE
... TABLE 2: ANTI-TUMOR EFFECT OF THYMOQUINONE Compound Study Models Effects Thymoquinone HCT-116 human colon Apoptotic effects of TQ on HCT-116 by ↑ Bcl-2 cancer cells protein and mRNA expr[r] ...
8
lncRNA SNHG6 regulates EZH2 expression by sponging miR-26a/b and miR-214 in colorectal cancer
... SNHG6 promotes CRC cell migration and invasion in vitro Subsequently, we explored the effects of SNHG6 on CRC metastasis. GSEA results indicated that SNHG6 ex- pression was significantly correlated with the expression of ...
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