HCV RNA
Different Hepatitis C Virus (HCV) RNA Load Profiles Following Seroconversion among Injecting Drug Users without Correlation with HCV Genotype and Serum Alanine Aminotransferase Levels
... of HCV infection among injecting drug users. Nineteen untreated HCV seroconverters were tested longitudinally for the presence of HCV RNA by reverse transcriptase (RT) PCR, and results were ...
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Comparison of a Newly Developed Automated and Quantitative Hepatitis C Virus (HCV) Core Antigen Test with the HCV RNA Assay for Clinical Usefulness in Confirming Anti HCV Results
... of HCV infection is mainly based on the detection of anti-HCV antibodies as a screening test with serum ...of HCV RNA in confirmatory ...the HCV core antigen test with the HCV ...
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Qualitative Detection of Hepatitis C Virus RNA: Comparison of Analytical Sensitivity, Clinical Performance, and Workflow of the Cobas Amplicor HCV Test Version 2 0 and the HCV RNA Transcription Mediated Amplification Qualitative Assay
... HCV RNA TMA qualitative test (HCV ...target HCV RNA is captured to magnetic particles coated with oligonucleotides com- plementary to the 5⬘ untranslated region of the HCV ...
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Comparison of Serum Hepatitis C Virus (HCV) RNA and Core Antigen Levels in Patients Coinfected with Human Immunodeficiency Virus and HCV and Treated with Interferon plus Ribavirin
... (undetectable HCV RNA at ...persistent HCV RNA under treatment (n ⫽ 198, ...undetectable HCV RNA under treatment and 6 months after stopping treatment (n ⫽ 93, ...undetectable ...
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Accurate quantification of hepatitis C virus (HCV) RNA from all HCV genotypes by using branched DNA technology
... of HCV genotype and HCV viremia levels has been the lack of a reliable method for RNA quantification which is unaffected by HCV genotypic ...of HCV RNA to comple- mentary ...
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Performance Evaluation of the VERSANT HCV RNA Qualitative Assay by Using Transcription Mediated Amplification
... (HCV) RNA by transcription-mediated amplification (TMA) was conducted according to the guidelines of the National Com- mittee for Clinical Laboratory Standards and the ...assay, HCV TMA, detected 95% ...
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Alanine aminotransferase, HCV RNA levels and pro inflammatory and pro fibrogenic cytokines/chemokines during acute hepatitis C virus infection
... chronic HCV infection ...of HCV RNA replication, liver inflammation and immuno-pathogenesis of HCV infec- ...and HCV RNA levels with IP-10 and MIP- 1 β ...and HCV ...
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Impact of Hepatitis C Virus (HCV) Genotypes on Quantification of HCV RNA in Serum by COBAS AmpliPrep/COBAS TaqMan HCV Test, Abbott Antiretroviral Therapy HCV RealTime Assay, and VERSANT HCV RNA Assay
... same HCV RNA quantitative method throughout follow-up for an HCV patient on ...of HCV RNA data from clinical trials should take into account the method used for viral ...since ...
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Stimulation of Hepatitis C Virus (HCV) Nonstructural Protein 3 (NS3) Helicase Activity by the NS3 Protease Domain and by HCV RNA-Dependent RNA Polymerase
... by HCV RdRp. Both NS3 helicase and NS5B RdRp are required for HCV RNA replication ...by HCV RdRp, the RdRp from West Nile virus, also a flavivirus, was used in the NS3FL helicase assay and ...
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HCV core antigen and HCV RNA in HIV/HCV co infected patients with different HCV genotypes
... active HCV infections appears stronger in treated than in untreated ...with HCV-RNA (R 2 = ...anti- HCV levels and of HCVAg would have a very high pre- dictive value for viremia, helping to ...
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Comparative Evaluation of the VERSANT HCV RNA 3 0, QUANTIPLEX HCV RNA 2 0, and COBAS AMPLICOR HCV MONITOR Version 2 0 Assays for Quantification of Hepatitis C Virus RNA in Serum
... of HCV genotyping and pretreatment viral load determination (4, 13, ...relevant HCV quantitative threshold of 2,000,000 copies/ml for use in the determination of the length of treatment with IFN-␣–ribavirin ...
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Comparison of Qualitative (COBAS AMPLICOR HCV 2 0 versus VERSANT HCV RNA) and Quantitative (COBAS AMPLICOR HCV Monitor 2 0 versus VERSANT HCV RNA 3 0) Assays for Hepatitis C Virus (HCV) RNA Detection and Quantification: Impact on Diagnosis and Treatment of HCV Infections
... of HCV infection is currently based on the detection of antibodies to ...qualitative HCV RNA determination, such as that measured by the HCV AMPLICOR ...of HCV RNA, but they ...
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The Cobas AmpliPrep/Cobas TaqMan HCV Test, Version 2 0, Real Time PCR Assay Accurately Quantifies Hepatitis C Virus Genotype 4 RNA
... the HCV life cycle have reached early to late clinical ...with HCV genotypes 1 to 4, including (i) triple combinations of pegylated IFN-␣, ribavirin, and a DAA or HTA, (ii) quadruple combinations of ...
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Development and clinical validation of the Genedrive point of care test for qualitative detection of hepatitis C virus
... Genedrive HCV assay is not fully automated, it is a user-friendly device and requires less than a day’s training to ...Xpert HCV assay is quantitative, the Genedrive HCV assay has potential ...
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Comparison of Conventional PCR with Real Time PCR and Branched DNA Based Assays for Hepatitis C Virus RNA Quantification and Clinical Significance for Genotypes 1 to 5
... the HCV RNA before detection by colorimetric measure- ments using specifically labeled primers or DNA ...of HCV RNA from very low to extremely high concentrations and therefore is considered ...
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Multicenter Comparison Study of both Analytical and Clinical Performance across Four Roche Hepatitis C Virus RNA Assays Utilizing Different Platforms
... cobas HCV real-time PCR-based assays were developed, namely the cobas HCV test for use on the cobas 6800 and cobas 8800 systems (cobas 6800/8800 HCV) and the cobas HCV test for use on the ...
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Effectiveness of HCV core antigen and RNA quantification in HCV infected and HCV/HIV 1 coinfected patients
... of HCV- RNA in HIV plasma may partly account for the higher Ag/RNA ratios in HCV/HIV-1-coinfected patients with lower CD4+ T-cell ...5, HCV/HIV-1-coinfected patients with an im- paired ...
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Hepatitis C treatment initiation in HIV HCV coinfected patients
... [23]. HCV infection was defined as a positive HCV serology, and/or a detectable HCV- RNA in ...for HCV), spontaneous cure (confirmed negative HCV-RNA in a patient with ...
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Most common HCV genotypes in patients from north-eastern Croatia
... of HCV-RNA positive patients in north-eastern Croatia were infected with genotype ...Routine HCV- RNA-based screenings of high-risk indi- viduals (such as injection drug users, young people ...
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JBC-2005-Huang-36417-28.pdf
... Because we could not use the NS5A sequence to gain insight into NS5A structure or function, we asked whether the NS5A binding spec- ificity was unique. If proteins of known structure and function with similar binding ...
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