Head and neck squamous cell carcinomas
A radiosensitivity MiRNA signature validated by the TCGA database for head and neck squamous cell carcinomas
... In Head and Neck Squamous cell carcinomas (HNSCC) for example, a comparative analysis of normal and cancerous tissues revealed that a handful of miRNAs were differentially regulated in ...
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Overexpression of TWIST2 correlates with poor prognosis in Head and Neck Squamous Cell Carcinomas
... Head and neck squamous cell carcinomas (HNSCC) are a heterogeneous group of tumors with variable presentation and clinical behavior. Despite improvements in surgical and radiation ...
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Unique DNA methylation signature in HPV-positive head and neck squamous cell carcinomas
... (HPV)(+)-associated head and neck squamous cell carcinomas (HNSCCs) have been recently shown to present characteristic mutations in various cancer-associated genes, including mutations ...
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Microbiomic differences in tumor and paired-normal tissue in head and neck squamous cell carcinomas
... lar, head and neck squamous cell carcinomas (HNSCC), which account for more than half a million cancer cases annually around the world [11, 12], has received relatively little ...
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Molecular classification of head and neck squamous cell carcinomas using patterns of gene expression.pdf
... in head and M.B., and Childs, G. (2002). Molecular classification of head and neck squa- neck squamous cell carcinomas from different tumor sites: construction of mous ...
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Prognostic Significance of Hematologic Markers in Patients with Head and Neck Squamous Cell Carcinomas
... the head and neck region, according to tumor ...with head and neck squamous cell carcinomas (HNSCC) between 2006 and ...
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Basal oxidative stress ratio of head and neck squamous cell carcinomas correlates with nodal metastatic spread in patients under therapy
... the cell to reduce GSSG to GSH is decreased, thereby resulting in the accumulation of GSSG within the ...the cell or it is reacted with protein sulfhydryl ...
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Impact of PI3K/AKT/mTOR pathway activation on the prognosis of patients with head and neck squamous cell carcinomas
... of S6 phosphorylation with clinicopathological parameters associated with a better prognosis (Supplementary Table S2) and improved disease-specific survival (Log-rank test, P = 0.003 and P = 0.001, Figure 2C and 2D). The ...
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Identification of new candidate therapeutic target genes in head and neck squamous cell carcinomas
... Among the 42 genes analyzed, our study reveals that 6 are relevant targets in head and neck squamous cell carcinoma: PGF, PDL1/CD274, CDK6, EGFR, MET, VEGFA. Almost a third of the tumors ...
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Whole Tumor Perfusion CT Parameters and Glucose Metabolism Measurements in Head and Neck Squamous Cell Carcinomas: A Pilot Study Using Combined Positron Emission Tomography/CT Imaging
... 6-fluoro,-two deoxyglucose (FDG), a scout, followed by low-dose (50 mA) CT attenuation correction scan (CTAC) in a 16-section multi- detector CT scanner (Discovery ST; GE Medical Systems, Milwaukee, Wis) was obtained ...
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Applications of radiomics in precision diagnosis, prognostication and treatment planning of head and neck squamous cell carcinomas
... augmentation – or even alternative – for traditional clinical testing and prognostication, if adequate perform- ance and stability is attained. Numerous studies in the past 6 years have reported potential applications of ...
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Toll like receptor 4 single nucleotide polymorphisms Asp299Gly and Thr399Ile in head and neck squamous cell carcinomas
... It is also believed that optimal therapeutic effects require the immunoadjuvant effect of DAMPs like HMGB1 released from tumor cells damaged by cyto- toxic anticancer agents. In other words, anticancer immune responses ...
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Over expression of BAG 1 in head and neck squamous cell carcinomas (HNSCC) is associated with cisplatin resistance
... Total RNA was extracted from each cell line using miRNA Easy Kit (Qiagen, Germantown, MD) and RNA was evalu- ated using NanoDrop 2000 (Thermo Scientific, Wilmington, DE). Microarray expression experiments were ...
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Prognostic value of FDG PET/CT in head and neck squamous cell carcinomas
... proven head and neck cancer and no radiological evidence of distant metastasis at the time of ...prior head and neck cancer, and those who had previously undergone neck surgery or ...
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MicroRNA Deregulations in Head and Neck Squamous Cell Carcinomas
... Therefore, microRNAs contribute a newly recognized level of gene expression regulation. The microRNA- mediated post-transcriptional regulation of gene expression is achieved through several mechanisms, including (1) ...
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Radiosensitization of HNSCC cells by EGFR inhibition depends on the induction of cell cycle arrests
... treat head and neck squamous cell carcinomas (HNSCC) which are predominantly p53 mutated, we tested the effects of EGFR targeting on cellular radiosensitivity, proliferation, apoptosis, ...
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HPV Induced Oropharyngeal Carcinoma - A critical review
... and head and neck squamous cell carcinomas were less likely to experience cancer recurrence than patients with HPV negative ...induced squamous cell carcinomas may ...
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A gene expression profile test to resolve head & neck squamous versus lung squamous cancers
... of squamous cell ...or head & neck in ...of squamous cell ...between squamous cell carcinomas from various primary sites as squamous cancers have ...
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Squamous cell carcinomas of the lung and of the head and neck: new insights on molecular characterization
... [4]. Squamous cell carcinoma (SCC) is the most frequent histotype among the head and neck ...of head and neck squamous cell carcinoma (HNSCC) has been observed: ...
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Head and neck cancer and occupational exposure to leather dust: results from the ICARE study, a French case-control study
... for head and neck overall, and pharyngeal squamous cell carcinomas increasing with each decade of exposure to leather ...for squamous cell carcinomas of ...
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