Heat Shock Protein
A Child Hereditary Motor Sensory Neuropathy and Mutation of Heat Shock Protein HSPB1
... Heat Shock protein beta-1 is a ubiquitously expressed, multifunctional protein chaperone. Mutations in HSPB1 result in the development of a late onset, hereditary motor neuropathy type II ...
6
Activity of the Heat Shock Protein 90 Inhibitor Ganetespib in Melanoma
... Heat shock protein 90 (HSP90) is a ubiquitous molecular chaperone that promotes the conformational maturation and stabilization of numerous client ...
9
Heat shock protein 90 in neurodegenerative diseases
... cyclin-dependent protein kinase 5; CMA: chaperone-mediated autophagy; CNS: central ner- vous system; DRPLA: Dentatorubral-pallidoluysian atro- phy; FTDP-17: frontotemporal dementia and parkinsonism linked to ...
8
The Role Of Protective Heat Shock Protein 70 And Proinflammatory Heat Shock Protein 60 Toward The Functional Status Of Acute Thrombotic Ischemic Stroke
... of Heat Shock Protein 70 and the effect of pro-inflammatory Heat Shock Protein 60 against Functional Status of Acute Thrombotic Ischemic Stroke, to assess stroke risk factors ...
7
THERMO-TOLERANCE AND HEAT SHOCK PROTEIN OF ESCHERICHIA COLI ATCC 25922 UNDER THERMAL STRESS USING TEST CELL METHOD
... the heat shock protein (HSP) induction (Schumann, 2003; ...min heat shock at 46 °C for ...h heat shock, their HSP70 and HSP60 levels clearly increased (Urban- Chmiel et ...
7
The Heat Shock Protein Story—From Taking mTORC1,2 and Heat Shock Protein Inhibitors as Therapeutic Measures for Treating Cancers to Development of Cancer Vaccines
... Heat shock protein 90 (HSP90), together with its co-chaperones, can help over 200 nascent polypeptides to fold correctly, eventually leading to synthesis of the proper proteins for constitutive cell ...
68
Docking of Human Heat Shock Protein 90 with Selenoderivatives of Geldanamycin
... human heat shock protein 90 (HSP90) in many signalling networks associated with cancer progression makes it an important drug ...from Protein Data Bank (PDB code: 1YET) based on ...
15
Anti-Vpr Activities of Heat Shock Protein 27
... another heat-shock protein, HSP70, has activities similar to those described here for HSP27: it suppresses Vpr-induced cell cycle arrest and apoptosis, and inhibits HIV replication ...the ...
11
Heat Shock Protein Genes in Fish
... small heat shock proteins play role in development and ...a heat shock protein homologous to human Hsp27/HSPB1 and characterized the phosphorylation, thermoprotective activities, and ...
7
Neuroprotection by heat shock protein 27 in sensory and motor neurons
... The ability o f the small heat shock protein 27 (Hsp27) to prevent apoptotic neuronal death has been examined in primary sensory and motor neurons. The first part o f the thesis investigates whether ...
162
A gene-specific non-enhancer sequence is critical for expression from the promoter of the small heat shock protein gene αB-crystallin
... Background: Deciphering of the information content of eukaryotic promoters has remained confined to universal landmarks and conserved sequence elements such as enhancers and transcription factor binding motifs, which are ...
13
Heat shock protein 70 promotes lipogenesis in HepG2 cells
... stress. Heat shock proteins (HSPs) are triggered by heat stress and other short-term and long-term ...stresses. Heat shock protein 70 is the most well-studied in response to ...
10
Characterization of Heat Shock Protein-Specific T Cells in Atherosclerosis
... express heat shock protein 60 (HSP60) and, since human (hHSP60) and bacterial (GroEL) HSP60s are highly conserved, the immune response to bacteria may result in cross-reactivity, leading to ...
9
Autoantibodies to the heat shock protein hsp90 in systemic lupus erythematosus
... 90,000-D heat-shock protein, hsp90, a molecule thought to have important functions in the cellular response to stress, virus-induced transformation, steroid hormone receptor action, and cellular ...
5
Localization of heat shock protein 20 in swine carotid artery
... Background: Cyclic nucleotides can relax vascular smooth muscle by mechanisms distal to myosin regulatory light chain (MRLC) phosphorylation. This mechanism, termed relaxation without MRLC dephosphorylation, may be ...
5
Heat Shock Protein 70: Roles in Multiple Sclerosis
... In MS, the immune response in the CNS leads to inflammatory and oxida- tive conditions that induce the overex- pression of most HSP (including Hsp70) in the CNS lesions of MS patients and in the EAE animal model of the ...
11
Nitric oxide induces heat shock protein 70 expression in vascular smooth muscle cells via activation of heat shock factor 1
... hsp70 protein accumulation in cultured Hep G2 and hepatocytes treated with NO ...to heat shock or stress remains to be ...regulating heat shock response in which the hsps them- selves ...
10
Heat shock factor 1 protein in heat shock factor 1 gene transfected human epidermoid A431 cells requires phosphorylation before inducing heat shock protein 70 production
... Phosphorylation of HSF1 occurs in response to heat (37, 40–42) or inducers of transcriptional activation such as cad- mium and arachidonic acid (35, 43). Although the level of HSF1 phosphorylation is thought to be ...
9
Heat shock protein expression and apoptosis in myeloid leukaemias
... Mehlen the of et stem cells via apoptosis al., embryonic murine In haemopoietic systems, studies of myeloid differentiation have shown that expression differentiation by is induced hsp70[r] ...
206
Heat Shock Protein 90 and Heat Shock Protein 70 Are Components of Dengue Virus Receptor Complex in Human Cells
... E protein and the cellular receptor present on the surface of the host ...E protein (9) or the native virion on the cell surface (13); however, it has been suggested that these mole- cules serve primarily ...
11