Heat Shock Protein Difference between Genotypes
Association between circulating levels of heat-shock protein 27 and aggressive periodontitis
... two heat-shock proteins investigated in this study, Hsp27 and Hsp60, may be part of a cell stress protein-cytokine network controlling inflammation in peri- odontal ...tion between circulating ...
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Heat shock protein 90 in neurodegenerative diseases
... Frequently, neurodegenerative diseases are characterized by a gain of toxic function of misfolded proteins. Here, toxicity may result from an imbalance between normal chaperone capacity and production of dangerous ...
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Response of circulating heat shock protein 70 and anti heat shock protein 70 antibodies to catheter ablation of atrial fibrillation
... associations between anti-HSP70 antibodies and AF type as well as HSP70 and anti-HSP70 antibody increases and AF recurrence after ablation may point to parallel phenomena or imply causality which remains to be ...
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Heat Shock Protein 70: Roles in Multiple Sclerosis
... MS PATHOGENESIS MS is a chronic and progressive neu- rodegenerative disease that is deemed to affect more than 2.1 million people worldwide (21). MS is considered an immune-mediated disease characterized by the presence ...
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Anti-Vpr Activities of Heat Shock Protein 27
... cellular heat shock responses are highly conserved among eukaryotes, we investigated the relation between Vpr and the human paralogue of Hsp16, ...
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Cross-Reactivity between Chlamydia trachomatis Heat Shock Protein 10 and Early Pregnancy Factor
... The passive immunization of pregnant mice with anti-EPF antibodies leads to the retardation of embryonic development and/or inhibition of implantation. The partial amino acid sequences obtained for platelet-de- rived EPF ...
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Multi-level interactions between heat shock factors, heat shock proteins, and the redox system regulate acclimation to heat
... crosstalk between the classical heat stress response, which consists of heat shock factors (HSFs) and heat shock proteins (HSPs), with the ROS network at multiple levels in the ...
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The Heat Shock Protein Story—From Taking mTORC1,2 and Heat Shock Protein Inhibitors as Therapeutic Measures for Treating Cancers to Development of Cancer Vaccines
... More HSPs are synthesized and released are the reasons for such a result, as ex- plained before. In fact, there are epidemiological studies showing negative cor- relation between the risk of cancer in persons with ...
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The Role Of Protective Heat Shock Protein 70 And Proinflammatory Heat Shock Protein 60 Toward The Functional Status Of Acute Thrombotic Ischemic Stroke
... Bertha Jean Que, Amiruddin Aliah, Irawan Yusuf, Cahyono Kaelan Abstract: Clinical experience suggests that the functional status of stroke patients is not directly proportional to the number of risk factors, this means ...
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Activity of the Heat Shock Protein 90 Inhibitor Ganetespib in Melanoma
... Abstract Heat shock protein 90 (HSP90) is involved in the regulation of diverse biological processes such as cell signaling, proliferation and survival, and has been recently recognized as a ...
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Identification of heat shock factor binding protein in Plasmodium falciparum
... in heat shock response attenuation by binding, destabilizing and dissociating HSF trimers to the inert monomers, in con- junction with ...of heat shock ...heat shock. Therefore, ...
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Investigating Evolutionary Innovation in Yeast Heat Shock Protein 90
... specific protein regions that may be important for adaptation to new ...the protein sequence and between environments, we identified hotspots of beneficial and deleterious mutations that are shared ...
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Docking of Human Heat Shock Protein 90 with Selenoderivatives of Geldanamycin
... contacts between regions of lower electronic density (σ-hole) of donor atoms and electron lone pairs of nucleophile atoms acting as sigma-hole acceptors [20], were not found in the inhibitor site of ...
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Neuroprotection by heat shock protein 27 in sensory and motor neurons
... balance between factors that promote survival or inhibit death versus those that induce death and suppress ...small heat shock protein Hsp27 has been recently implicated as having a role in ...
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Characterization of Heat Shock Protein-Specific T Cells in Atherosclerosis
... DISCUSSION The results of the present study have shown cross-reactivity in a number of GroEL- and hHSP60-specific T-cell lines to hHSP60 and GroEL, respectively. Since the hHSP60 antigen used contained no GroEL, these ...
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The 90 kda heat shock protein 90 (Hsp90) is a molecular
... binding site. Interestingly, this pyrrolidine ring projects into a subpocket that allows for the inclusion of additional sub- stituents. However, homologation of the linker length may diminish hydrogen-bonding ...
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Heat shock protein 70 promotes lipogenesis in HepG2 cells
... association between HSP70 and fatty liver, we first evaluated the expression of HSP70 in the livers of obese ...the protein expression of HSP70 in the liver was up-regulated in obese mice compared with ...
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Activity of the Heat Shock Protein 90 Inhibitor Ganetespib in Melanoma
... Abstract Heat shock protein 90 (HSP90) is involved in the regulation of diverse biological processes such as cell signaling, proliferation and survival, and has been recently recognized as a ...
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Death versus survival: functional interaction between the apoptotic and stress inducible heat shock protein pathways
... interactions between Hsp90 and its target proteins (124, ...interactions between other Hsp family members and their target proteins has yet to be ...
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Characterization of the relationship between the chaperone and lipid-binding functions of the 70-kDa heat-shock protein, HspA1A
... this protein does not contain any known lipid-binding domains or other PM translocation ...the protein from translocating to the PM while still maintaining its chaperone ...
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