Hematopoietic stem cell
Children as Hematopoietic Stem Cell Donors
... half-century, hematopoietic stem cell transplantation has become standard treatment for a variety of diseases in children and adults, including selected hematologic malignancies, immunodeficien- cies, ...
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Allogeneic hematopoietic stem cell transplantation: transfusion issues
... Allogeneic hematopoietic stem cell transplantation (AHSCT) is an intention-to-cure treatment strategy in several malignancies and ...red cell and platelet engraftment, the patients are usually ...
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Hematopoietic stem cell transplantation for the management of follicular lymphoma
... patients were randomized to three more cycles of the same chemotherapy (C), or HDT followed by autologous unpurged (U) or purged (P) HSCT. Purging was performed using a cocktail of monoclonal antibodies. Of the 140 ...
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ABO Incompatibility and Hematopoietic Stem Cell Transplantation Outcomes
... allogeneic hematopoietic stem cell transplantation (HSCT) and ABO incompatibility is not considered a barrier, but it seems that erythrocyte recovery delay and hemolytic complications maybe a problem ...
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Sex chromosome loss after allogeneic hematopoietic stem cell transplant in patients with hematologic neoplasms: a diagnostic dilemma for clinical cytogeneticists
... matched hematopoietic stem cell transplant (HSCT) is considered a highly effective treatment or even a permanent cure for several hematologic ...
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Hematopoietic stem cell transplantation
... for hematopoietic stem cell transplantation (HSCT) depend on the patient’s medical condition, the therapeutic objectives, and the availability and source of stem cells (Table ...
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Hematopoietic Stem Cell Transplantation in Hemophagocytic Lymphohistiocytosis: A Single-Center Report of 48 Patients
... T cell–mediated and natural ...remission. Hematopoietic stem cell transplantation (HSCT), however, is the only curative option, but optimal modalities and long-term outcome are not yet well ...
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Hematopoietic stem cell emergence in the conceptus and the role of Runx1
... of hematopoietic cells from purified endothelial cells ex vivo, suggesting a role for Runx1 in the hemogenic endothelium to hematopoietic cell transition (North et ...impedes hematopoietic ...
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Hematopoietic stem cell development in the placenta
... of cell tracing technologies has now made it possible to verify the hypothesis that HSCs are generated from the ...revealed hematopoietic potential in the endothelial cells in the AGM, the placenta and the ...
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Regulation of human hematopoietic stem cell lineage commitment
... My thesis projects focus on identifying and characterizing regulatory factors involved in myeloid commitment steps for human hematopoietic stem and progenitor cells (HSPCs), so as [r] ...
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Of birds and mice: hematopoietic stem cell development
... to hematopoietic development, undertaken at the end of the XIXth century, was based on the observation of embryos at various development ...from cell aggregates initially identical in shape, the blood ...
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The hematopoietic stem cell niche: from embryo to adult
... and hematopoietic cells (Matsuoka et ...endothelial cell lines, DAS-104-8 and DAS-104-4, were found to support HSC differentiation and maintenance in the fetal liver, respectively (Ohneda et ...
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Hematopoietic stem cell transplantation for HIV cure
... Two newer approaches to gene editing include transcription activator–like effectors nucleases (TALENs) and engineered clus- tered regularly interspaced palindromic repeats (CRISPR) coupled to a CRISPR-associated (Cas) ...
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Pancytopenia as a clonal disorder of a multipotent hematopoietic stem cell
... Hematopoiesis was investigated in a 14-yr-old girl who had a 2-yr history of stable asymptomatic pancytopenia and who was also heterozygous at the structural locus for glucose-6-phosphate dehydrogenase (G-6-PD). There ...
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Inhibiting HDAC for human hematopoietic stem cell expansion
... exactly in the serum was acting to decrease activity for the output of HSCs. Many different cell populations, cell-derived cytokines, and other factors can act as negative regulators of HSCs (6, 7, 11). ...
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Molecular Imaging of Stem Cells: Tracking Survival, Biodistribution, Tumorigenicity, and Immunogenicity
... homeostatic stem cells examined the skin stem cell niche in transgenic mice ...on hematopoietic stem cell survival compared to GFP for long-term imaging ...
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Understanding Megakaryopoiesis And Thrombopoiesis Using Human Stem Cells Models
... term-hematopoietic stem cell (LT- HSC) and the short term-hematopoietic stem cell (ST-HSC) in the bone marrow are at the top of the hematopoietic hierarchy and give rise ...
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New Insights of Human Parvovirus B19 in Modulating Erythroid
... essential regulators of hematopoietic stem cell development downstream of Notch signaling. Notch1 inhibits 567[r] ...
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A review paper on stem cells
... 1991). Hematopoietic stem cell transplants (SCT) were used in the treatment of neoplastic diseases, in addition to congenital, autoimmune, and inflammatory disorders (Talmadge, ...adult stem ...
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Effects of Mesenchymal Stem Cell Derivatives on Hematopoiesis and Hematopoietic Stem Cells
... of hematopoietic stem cell markers CD34, CD45, CD117 (cKit), HLA class I, HLA-DR (except for HLA-ABC) and lineage- specific markers are important indicators of MSC immunophenotyping for detection of ...
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