Hemoglobin variant
![A new hemoglobin variant, hemoglobin Nunobiki [alpha 141 (HC3) Arg Cys] Notable influence of the carboxy terminal cysteine upon various physico chemical characteristics of hemoglobin](data:image/gif;base64,R0lGODlhAQABAIAAAP///wAAACH5BAEAAAAALAAAAAABAAEAAAICRAEAOw==)
A new hemoglobin variant, hemoglobin Nunobiki [alpha 141 (HC3) Arg Cys] Notable influence of the carboxy terminal cysteine upon various physico chemical characteristics of hemoglobin
... new hemoglobin variant, hemoglobin (Hb) Nunobiki, was detected in a Japanese male with marginal ...total hemoglobin. Structural analysis of this variant established the substitution of ...
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Hemoglobin Rahere, a human hemoglobin variant with amino acid substitution at the 2,3 diphosphoglycerate binding site Functional consequences of the alteration and effects of bezafibrate on the oxygen bindings
... abnormal hemoglobin (Rahere), with a threonine residue replacing the beta 82 (EF6) lysine residue at the binding site of 2,3-diphosphoglycerate, which was responsible for overt erythrocytosis in two individuals of ...
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Hemoglobin Brigham (α2Aβ2100 Pro→Leu) HEMOGLOBIN VARIANT ASSOCIATED WITH FAMILIAL ERYTHROCYTOSIS
... the hemoglobin were normal, but on peptide mapping of a tryptic digest of the isolated b-chains, a normal bT11 peptide and an abnormal bT11 with greater R f were ...
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Hemoglobin Abraham Lincoln, β32 (B14) Leucine → Proline AN UNSTABLE VARIANT PRODUCING SEVERE HEMOLYTIC DISEASE
... An unstable hemoglobin variant was identified in a Negro woman with hemolytic anemia since infancy. A splenectomy had been performed when the patient was a child. The anemia was accompanied by erythrocyte ...
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Hemoglobin Olympia (β20 Valine → Methionine): An Electrophoretically Silent Variant Associated with High Oxygen Affinity and Erythrocytosis
... In a family with erythrocytosis, electrophoretic and chromatographic studies failed to demonstrate a hemoglobin variant. However, the oxygen dissociation curves of affected individuals were shifted to the ...
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Hemoglobin Syracuse (alpha2beta2 143(H21)His leads to Pro), a new high affinity variant detected by special electrophoretic methods Observations on the auto oxidation of normal and variant hemoglobins
... abnormal hemoglobin bands were seen after electrophoresis on starch gel at pH ...patient's hemoglobin focused at a more acid pH than hemoglobin A, indicating a hemoglobin variant with ...
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Haematological profile of sickle cell patients attending tertiary health care centre of southern odisha: a cross sectional study
... hypochromic to normocytic hypochromic) and High Hb F dominated the hematological profile whereas in heterozygous cases mild anaemia (microcytic hypochromic) dominated the hematological profile. In this study, children ...
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Hemoglobinopathic Erythrocytosis due to a New Electrophoretically Silent Variant, Hemoglobin San Diego (β109(G11)Val→Met)
... characterized by a high affinity for oxygen. Compositional analyses of all tryptic peptides from the b-chains of the proband revealed a valyl-methionyl ambiguity in bT12a. Blockage of lysyl residues and subsequent ...
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Hemoglobin Louisville (β42 (CD1) Phe→Leu): an unstable variant causing mild hemolytic anemia
... unstable hemoglobin variant termed Hb Louisville, was found in four members of a Caucasian family, who were suffering from a mild hemolytic ...The variant showed a decreased stability upon warming at ...
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The predominance of codon 39 (c>t) mutation of HBB gene in a portion of the Algerian population (Northeast Algeria)
... for the second time in the Algerian population. In this study, we detect a rare hemoglobin variant caused by a mutation in β-globin gene, HBB: c.82G>T: Codon 27 GCC>TCC (Ala-Ser), Hb Knossos, which ...
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Hemoglobin NYU, a delta chain variant, α2δ212Lys
... minor hemoglobin (Hb) component with the electrophoretic properties of the d-chain variant Hb A 2¢ was encountered in two unrelated families of Russian-Jewish ...that hemoglobin A 2¢ isolated from ...
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Observations on the Inheritance of Sickle Cell Hemoglobin and Hemoglobin C
... Furthermore, if filter paper electrophoresis was allowed to proceed for a longer period, this faster component of hemoglobin migrated to a position consistent with the migration of fetal[r] ...
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Z-SCORE FOR HOMOLOGY MODELING AND STRUCTURE PREDICTION OF GLOBULAR PROTEIN OF HOMOSAPIENS & PLANT
... The stability of protein structures in solvent is the function of their atomic coordinates. The solvation free energy is the product of the atomic solvation parameter and of the atom accessibility to solvent. The ...
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Imaging in breast cancer: Diffuse optics in breast cancer: detecting tumors in pre menopausal women and monitoring neoadjuvant chemotherapy
... A substantial body of work has emerged over the past decade that demonstrates how tomographically based DOI methods can accurately localize subsurface structures. Optimal clinical decision-making, however, requires ...
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HYPOCHROMIC MICROCYTIC ANEMIA OF INFANCY: IRON DEPLETION AS A FACTOR
... In the first of the 2 children, the formation of new hemoglobin was relatively slow, so that over the period of a year the concentration of hemoglobin slowly fell. The gain in hemoglobin[r] ...
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Assessment of complete blood count in Patients with Chronic Renal failure
... the Hemoglobin, Hematocrit, Red Blood Cells count and Mean Cell Hemoglobin Concentration (P-value = ...the Hemoglobin, Hematocrit, Red Blood Cells count, Mean Cell Hemoglobin and Mean Cell ...
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Functional and physicochemical studies of hemoglobin St Louis beta 28 (B10) Leu replaced by Gln: a variant with ferric beta heme iron
... represented 30% of the total and was isolated by starch block electrophoresis at pH 8.6. Electrophoretic and spectral studies showed Hb St. Louis to be a valency hybird, alpha 2 beta 2+. The presence of hemichrome in ...
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Water regulates oxygen binding in hagfish (Myxine glutinosa) hemoglobin
... affinity in M. glutinosa hemoglobin (Fago et al., 1999), is transported within the red blood cells rather than in plasma. Hagfishes are probably the only marine organisms to have evolved without entering ...
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Iron treatment of pregnant sows in a Danish herd without iron deficiency anemia did not improve sow and piglet hematology or stillbirth rate
... The sows were restrained using a snare and blood was withdrawn into each of 10 mL EDTA (BD Vacutainer, K2E 18.0 mg, BD, Plymouth, UK) and plain (BD Vacu- tainer CAT (Clot Activator Tube, BD, Plymouth, UK) tubes from the ...
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Hemoglobin binding activity and hemoglobin-binding protein of Prevotella nigrescens
... established hemoglobin-envelope complex formed in the pH ...solution, hemoglobin released entirely from the ...among hemoglobin and the envelope is rightly recipro- cal; HbbP in the envelope prefers ...
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