hemophilia B
Manual therapy in the treatment of patients with hemophilia B and inhibitor
... with hemophilia B and inhibitor received physiotherapy treatment based on manual therapy for 3 months, with a frequency of 2 sessions per ...the Hemophilia Joint Health Score; pain was assessed with ...
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Treatment of hemophilia B: focus on recombinant factor IX
... Abstract: Hemophilia B is a recessive X-linked bleeding disorder characterized by deficiency of the coagulation factor IX ...In hemophilia B patients the severity of the bleeding phe- notype ...
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<p>Mild-severe hemophilia B impacts relationships of US adults and children with hemophilia B and their families: results from the B-HERO-S study</p>
... that hemophilia affected their ability to form close relationships with partners or prospective partners; 35% were very/quite dissatis fi ed with the support received from a previous ...their hemophilia ...
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Molecular Characterization of the Factor IX Gene in 28 Iranian Hemophilia B Patients
... Hemophilia B, or Christmas disease, is an X- linked coagulopathy due to the deficiency or functional abnormality of clotting factor IX ...of hemophilia B is approximately one in 25000-30000 ...
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Partial factor IX protein in a pedigree with hemophilia B due to a partial gene deletion
... A partial gene product was identified in a pedigree with hemophilia B due to a partial deletion of the Factor IX gene (Chen, S.-H.,S. Yoshitake, P.F. Chance, G.L. Bray, A.R. Thompson, C.R. Scott, and K. ...
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GlycoPEGylated recombinant factor IX for hemophilia B in context
... over hemophilia treatment selection and switching involve balancing many clinical and patient-related ...philia B is prophylaxis with plasma-derived or recombinant factor IX (rFIX) ...with hemophilia ...
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New developments in the management of moderate-to-severe hemophilia B
... Abstract: Hemophilia B is an X-linked genetic deficiency of coagulation factor IX (FIX) activity associated with recurrent deep tissue and joint bleeding that may lead to long-term ...from hemophilia ...
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<p>Correlations between patient-reported outcomes and self-reported characteristics in adults with hemophilia B and caregivers of children with hemophilia B: analysis of the B-HERO-S study</p>
... the B-HERO-S study have been previously ...for Hemophilia B, Hemophilia Federation of America, and National Hemophilia ...with hemophilia B (n=299) or caregivers of a ...
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Once-weekly prophylactic dosing of recombinant factor IX improves adherence in hemophilia B
... with hemophilia A received the ...in hemophilia B versus 53% in hemophilia A) and also present in patients > 18 years of age (20% versus ...Moderate hemophilia B is diagnosed ...
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Genetic variants of hemophilia B: detection by means of a specific PTC inhibitor
... Hemophilia B can be divided into at least two mutant forms different from the mild, moderate, and severe categories previously ...of hemophilia B patients, PTC-inhibitor-neutralizing activity ...
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Heterogeneity of the factor IX locus in nine hemophilia B inhibitor patients
... shown to have total deletions of the factor IX gene. Two other inhibitor patients, the brothers, were shown to have a presumably identical complex rearrangement of the factor IX gene involving two separate deletions. The ...
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Developments in the treatment of hemophilia B: focus on emerging gene therapy
... Abstract: Hemophilia B is a genetic disorder that is characterized by a deficiency of clotting factor IX (FIX) and excessive ...with hemophilia B are ideal candidates for gene therapy, mostly ...
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An intragenic deletion of the factor IX gene in a family with hemophilia B
... A family of seven patients severely afflicted with hemophilia B has been studied for their factor IX genes through the use of factor IX cDNA and genomic DNA probes. The patients had detectable (less than ...
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Hemophilia B (Christmas Disease) in a Female
... philia B, with a great amount of in-breeding, have been investigated,12hi no case of homo- zygous hemophilia B in a female due to mating between a hemophilic father and a carrier.. mothe[r] ...
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Carrier detection of Hemophilia B by using a restriction site polymorphism associated with the coagulation Factor IX gene
... coagulation and immunological assays, to follow the segregation of an abnormal FIX gene in a large Hemophilia B family. Among the six potential female carriers, functional assays showed that four had a high ...
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Unmasking Acquired hemophilia B disguised in an elderly male on Warfarin treatment – a case report and literature review.
... Patient was diagnosed as acquired Hemophilia B and was restored on Warfarin therapy. Factor IX monitoring was advised instead of the conventional care to keep INR within the target range. Patient was ...
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To study the occurrence of inhibitors in children affected with hemophilia ‘A’ and hemophilia ‘B’ disease
... 100 hemophilia patients attending OPD (81hemophilia A and 19 hemophilia B) in 2012-2013 were screened for presence of ...from hemophilia patients were appropriately processed, stored and sent ...
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Hemophilia B: Molecular pathogenesis and mutation analysis
... with hemophilia B in whom mutations have not been identified by F9 genomic DNA ...to hemophilia A, few studies have been published on F9 cDNA ...
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Hemophilia B (Christmas disease) variants and carrier detection analyzed by DNA probes
... Studies using both the genomic and cDNA probes confirmed that the variant 1.8-kb fragment was present in each obligate carrier and in each of the two carriers identified by RFLP analysis[r] ...
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Lymphocyte subsets in hemophilic patients with hepatitis C virus infection with or without human immunodeficiency virus co-infection: a nested cross-sectional study
... had hemophilia A (factor VIII defi- ciency). Because patients with hemophilia A generally required more intensive clotting factor replacement ther- apy as well as product (Factor VIII concentrate) that was ...
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