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Hemorrhagic Shock

Initial resuscitation of hemorrhagic shock

Initial resuscitation of hemorrhagic shock

... crystalloid solutions. However, colloid solutions are more expensive, may bind and decrease serum ionized calcium, decrease circulating levels of immunoglobulines, and may further compromise the extracellular fluid ...

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Bench to bedside review: Latest results in hemorrhagic shock

Bench to bedside review: Latest results in hemorrhagic shock

... Bleeding control, maintenance of tissue oxygenation with fluid resuscitation, coagulation support, and maintaining normo- thermia remain mainstays of therapy for patients with hemor- rhagic shock. However, further ...

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Systemic and microcirculatory effects of blood transfusion in experimental hemorrhagic shock

Systemic and microcirculatory effects of blood transfusion in experimental hemorrhagic shock

... traumatic hemorrhagic shock, the persistence of microcirculatory alterations after resuscitation predicted the develop- ment of multiorgan failure ...

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Esophageal capnometry during hemorrhagic shock and after resuscitation in rats

Esophageal capnometry during hemorrhagic shock and after resuscitation in rats

... Studies have demonstrated that an increase in veno–arterial P CO 2 gradient could be a reliable marker of tissue hypoperfu- sion [28–32]. Knichwitz and coworkers [25] demonstrated that continuous intramucosal P CO 2 ...

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Resveratrol Improves Survival and Prolongs Life Following Hemorrhagic Shock

Resveratrol Improves Survival and Prolongs Life Following Hemorrhagic Shock

... orrhagic shock/resuscitation models, in shorter term studies ...in hemorrhagic shock involves alterations in multiple different pathways that lead to cellular dysfunction and cell death leading to ...

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Studies on Myocardial Metabolism  III  Coronary Blood Flow, Myocardial Oxygen Consumption and Carbohydrate Metabolism in Experimental Hemorrhagic Shock

Studies on Myocardial Metabolism III Coronary Blood Flow, Myocardial Oxygen Consumption and Carbohydrate Metabolism in Experimental Hemorrhagic Shock

... This report deals with a study of changes in coronary flow and myocardial oxygen consumption in experimental hemorrhagic shock and with the effect of these changes on the myocardial meta[r] ...

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THE NATURE AND MECHANISM OF THE HEMOSTATIC BREAKDOWN IN THE COURSE OF EXPERIMENTAL HEMORRHAGIC SHOCK

THE NATURE AND MECHANISM OF THE HEMOSTATIC BREAKDOWN IN THE COURSE OF EXPERIMENTAL HEMORRHAGIC SHOCK

... THE CLOT ACCELERATING PROPERTY IN VIVO SERUM FROM A RABBIT IN THE EARLY PHASE OF HEMORRHAGIC SHOCK INJECTED INTO A NORMAL ANIMAL Thromboplastin generation test, using the transfused anim[r] ...

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Does vasopressor therapy have an indication in hemorrhagic shock?

Does vasopressor therapy have an indication in hemorrhagic shock?

... the hemorrhagic shock or traumatology setting compared different therapeutic strategies with and without vaso- pressor ...in hemorrhagic shock management was not asso- ciated with any obvious ...

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Lymphocyte Depletion in Experimental Hemorrhagic Shock in Swine

Lymphocyte Depletion in Experimental Hemorrhagic Shock in Swine

... following hemorrhagic shock, contributing to acute respiratory dis- tress syndrome, a significant etiology of morbidity and mor- tality after trauma ...

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Neuromodulation as a new avenue for resuscitation in hemorrhagic shock

Neuromodulation as a new avenue for resuscitation in hemorrhagic shock

... Hemorrhagic shock (HS), a major cause of early death from trauma, accounts for around 40% of mortality, with 33 – 56% of these deaths occurring before the patient reaches a medical ...

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Profile of Circulating Vasoactive Substances in Hemorrhagic Shock and Their Pharmacologic Manipulation

Profile of Circulating Vasoactive Substances in Hemorrhagic Shock and Their Pharmacologic Manipulation

... during hemorrhagic shock seems temporally correlated with blood CA levels (and not PRA), and the renin-AII system contributes to the maintenance of vascular resistance and may markedly decrease perfusion of ...

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Potential role of therapeutic hypothermia in the salvage of traumatic hemorrhagic shock

Potential role of therapeutic hypothermia in the salvage of traumatic hemorrhagic shock

... Hemorrhage remains the primary potentially preventable cause of death on battlefi elds and the second leading cause of death in civilian trauma [1,2]. Unfortunately, an estimated 56% of deaths occur during the ...

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Thromboelastometry guided hemostatic therapy for hemorrhagic shock in the postoperative period of vascular surgery: a case report

Thromboelastometry guided hemostatic therapy for hemorrhagic shock in the postoperative period of vascular surgery: a case report

... The present surgery was performed under general anesthesia, with hemodynamic instability throughout the procedure, which required norepinephrine. Iliac dissection technique was difficult; there was loss of blood and a ...

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MALP-2 pre-treatment modulates systemic inflammation in hemorrhagic shock

MALP-2 pre-treatment modulates systemic inflammation in hemorrhagic shock

... Animals were randomly distributed to five experimental groups. Each group consisted of six mice and the end- point in all experiments was six hours. Control animals were sacrificed directly after induction of anesthesia ...

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Evaluation of capillary leakage after vasopressin resuscitation in a hemorrhagic shock model

Evaluation of capillary leakage after vasopressin resuscitation in a hemorrhagic shock model

... Hemorrhagic shock (HS) represents a major threat to trauma and spontaneous bleeding patients ...profound shock, making the patient unresponsive to fluid resuscitation and ...vasodilatory ...

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Pre-Hospital Induced Hypothermia Improves Outcomes in a Pig Model of Traumatic Hemorrhagic Shock

Pre-Hospital Induced Hypothermia Improves Outcomes in a Pig Model of Traumatic Hemorrhagic Shock

... The present study analyzed the effect of pre- hospital induced hypothermia on hemodynam- ic and coagulation parameters in a pig model of multiple trauma. Lower heart rates were observed in the HT group than in the NT ...

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Metabolic networks in a porcine model of trauma and hemorrhagic shock demonstrate different control mechanism with carbohydrate pre feed

Metabolic networks in a porcine model of trauma and hemorrhagic shock demonstrate different control mechanism with carbohydrate pre feed

... hemorrhagic shock. The metabolic component of the response to hemorrhagic shock and traumatic injury is examined here in a model that is de- signed to (1) assess the metabolic effect of ...

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Metabolic networks in a porcine model of trauma and hemorrhagic shock demonstrate different control mechanism with carbohydrate pre-feed

Metabolic networks in a porcine model of trauma and hemorrhagic shock demonstrate different control mechanism with carbohydrate pre-feed

... trauma, hemorrhagic shock, and resuscitation according to whether pigs were fasted or fed carbohydrate before ...and hemorrhagic shock as a result of carbohydrate pre-feeding in metabolomics ...

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Effects of synthetic colloids on oxidative stress and inflammatory response in hemorrhagic shock: comparison of hydroxyethyl starch 130/0 4, hydroxyethyl starch 200/0 5, and succinylated gelatin

Effects of synthetic colloids on oxidative stress and inflammatory response in hemorrhagic shock: comparison of hydroxyethyl starch 130/0 4, hydroxyethyl starch 200/0 5, and succinylated gelatin

... of hemorrhagic shock as a disease of decreased perfusion and altered ...for hemorrhagic shock have targeted volume restoration and the prevention and amelioration of the immune and ...

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Hypertonic Saline in the Treatment of Hemorrhagic Shock

Hypertonic Saline in the Treatment of Hemorrhagic Shock

... of hemorrhagic shock” in the most popular databases including MEDLINE, the Cochrane Collaboration Database, the Center for Research Support, TRIP Database, PubMed, Web of Science, and Google ...

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