heparin-binding growth factor(s)
Analysis of fibroblast growth factor-heparin interactions
... fibroblast growth factors (FGFs), HS binding controls their transport between cells and is required for the assembly of a high affinity signaling complex with the cognate FGF ...their heparin ...
136
Heparin binding epidermal growth factor (HB EGF) drives EMT in patients with COPD: Implications for disease pathogenesis and novel therapies
... 21. Eapen MS, Myers S, Lu W, Tanghe C, Sharma P, Sohal SS. sE-cadherin and sVE- cadherin indicate active epithelial/endothelial to mesenchymal transition (EMT and EndoMT) in smokers and COPD: implications for new ...
16
Heparin binding ligands mediate autocrine epidermal growth factor receptor activation In skin organ culture
... of growth factor regulation during wound healing (58, ...EGF-like growth factors that bind heparin; ...EGF-like growth factors and sulfated proteoglycans such as tenascin may be ...
12
Heparin binding EGF like growth factor contributes to reduced glomerular filtration rate during glomerulonephritis in rats
... merization induced during dimerization and autophos- phorylation of 1 or more members of the EGF-R family (Erb-1 to Erb-4). HB-EGF is reported to bind to Erb-1 and Erb-4 with differing results in terms of chemotaxis and ...
11
Production of heparin binding epidermal growth factor like growth factor in the early phase of regeneration after acute renal injury Isolation and localization of bioactive molecules
... that heparin-binding epidermal growth factor-like growth factor (HB-EGF) mRNA is in- duced in the rat kidney after acute ischemic ...cosides. Heparin-binding ...
12
M2 macrophages induce ovarian cancer cell proliferation via a heparin binding epidermal growth factor/matrix metalloproteinase 9 intercellular feedback loop
... additional growth factor, the HB-EGF would be depleted from the media over ...of growth factor relative to the cellular receptor number ...transforming growth factor beta ...
13
Localization of heparin binding EGF like growth factor in the smooth muscle cells and macrophages of human atherosclerotic plaques
... Heparin-binding EGF-like growth factor (HB-EGF) is a potent chemoattractant and mitogen for smooth muscle cells (SMC) in culture. To elucidate whether HB-EGF is implicated in the pathogenesis ...
9
Modulation of fibroblast growth factor 2 receptor binding, dimerization, signaling, and angiogenic activity by a synthetic heparin mimicking polyanionic compound
... fibroblast growth factor (FGF-2) and other heparin-binding growth ...on binding to ...Unlike heparin, RG-13577 alone failed to mediate dimeriza- tion of ...abrogated ...
12
Heparin binding EGF like growth factor is an autocrine growth factor for human urothelial cells and is synthesized by epithelial and smooth muscle cells in the human bladder
... tumor growth are poorly understood, although a variety of studies have shown that urine contains bioactive substances that may play impor- tant roles in proliferative urothelial abnormalities ...tumor ...
10
Keratinocyte growth factor and hepatocyte growth factor/scatter factor are heparin binding growth factors for alveolar type II cells in fibroblast conditioned medium
... fibroblast growth factor, epidermal growth factor, and ...The growth factor activity bound to heparin-Sepharose and was eluted with ...keratinocyte growth ...
10
Augmented production of heparin binding mitogenic proteins by preadipocytes from massively obese persons
... the heparin-binding (fibroblast) growth factor family was indicated by Western blot analysis, for a 66-kD protein with anti-(1-24)bFGF, and for a 32-kD protein with anti-(40-63)bFGF ...of ...
7
Original Article Expression of heparin-binding epidermal growth factor in the endometrium is positively correlated with IVF-ET pregnancy outcome
... Al-Ghamdi et al. found that endometrial thick- ness was positively correlated with pregnancy rate, and endometrial thickness of at least 11 mm was most suitable for pregnancy [12]. Therefore, we further investigated the ...
6
Induction of heparin binding epidermal growth factor like growth factor mRNA in rat kidney after acute injury
... identified heparin-binding EGF-like growth factor (HB-EGF) is regulated in response to renal injury induced by either ischemia/reperfusion or mercuric ...
9
Mussel-inspired human gelatin nanocoating for creating biologically adhesive surfaces
... and growth on the modified surfaces was assessed using human umbilical endothelial ...cells. Binding of gelatin onto titanium was significantly enhanced by dopamine ...the binding of ...
13
Role of Heparin Binding in Plasmin-mediated Activation of TAFI and Thermal Stability of TAFIa
... of heparin, when compared to the wild-type ...of heparin. When examining the effect of heparin on the half-lives of all of the above variants, half-life fold increase is the lowest for K327A, ...
111
Biphasic monopolar electrical stimulation induces rapid and directed galvanotaxis in adult subependymal neural precursors
... Endogenous direct current electric fields (DCEFs) play important roles in physiological processes that include development, wound healing, nerve growth and angiogen- esis [13-17]. On a cellular level, it has long ...
13
The Roles of β-Adrenergic Receptor Blockers in Interstitial Cystitis
... Finally, angiogenesis is a complex process involving the coordinated steps of endothelial cell activation, proliferation, migration, tube formation, and capillary sprouting, and it requires the participation of many ...
17
Insulin-like Growth Factor Binding Proteins.pdf
... muscle cells secrete a serine protease for insulin like growth insulin-like growth factor binding proteins 1 and 3 on. factor binding protein-2[r] ...
18
Zhou, Rui (2003): Functional analysis of insulin-like growth factor binding protein -4 and -6 in transgenic mice. Dissertation, LMU München: Tierärztliche Fakultät
... fetal growth obviously increases the need for growth-promoting factors such as ...fetal growth during pregnancy, whereas the PAPP-A activity in maternal circulation is inhibited by complex formation ...
165
Building Muscle: The Role of Insulin-Like Growth Factor Binding Protein-6 and Insulin-Like Growth Factors in the Differentiation of Placental Mesenchymal Stem Cells into Skeletal Muscle
... During muscle differentiation, MAPK signals play an important role (12). Marshall et al. reported that a prolonged activation of ERK1/2, leads to differentiation, whereas, a transient activation of ERK1/2 leads to ...
248