Hepatic Fibrosis
The roles of lncRNA in hepatic fibrosis
... The long intergenic non-coding RNA-p21 (lncRNA- p21), which resides 15 Kb upstream of the gene encod- ing the critical cell cycle regulator Cdkn1a (also known as p21), contains two exons comprising 3.1 Kb [47]. ...
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Matrix Mechanics as Regulatory Factors and Therapeutic Targets in Hepatic Fibrosis
... repair, fibrosis, and so on ...after fibrosis occurs, this balance will be broken and the profibrogenic effects of TIMP-1 are thought to be mediated via preventing collagen degradation through inhibition of ...
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Correlation of sTREM-1 content with hepatic fibrosis, inflammatory response and oxidative stress response in hepatic infective ascites
... Liver fibrosis is an important pathological link of decompensated cirrhosis to aggravate liver function damage, and the metabolism disorder of collagen and non-collagen in extracellular matrix is closely related ...
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Original Article Erythropoietin improves hepatic fibrosis via suppression of hepatic stellate cells and macrophage activation
... in hepatic fibrosis and have become a major therapeutic target in pre- vention and treatment of liver cirrhosis ...of hepatic hydroxyproline were gradually increased in the CCl 4 group, but were ...
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The role of microRNAs in the pathogenesis, grading and treatment of hepatic fibrosis in schistosomiasis
... are hepatic granuloma and fibrosis due to worm ...by hepatic fibrosis are usually the main causes of death in patients with chronic hepatosplenic ...schistosomiasis-induced hepatic ...
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Evaluation of Rumex hastatus leaves against hepatic fibrosis: a rat model
... treatment are ineffective and few in long-term process have intolerable side effects that is why recently researcher have focused on the use of effective antioxidant for assess- ment against hepatic ...
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Tyrosine kinase inhibitors: friends or foe in treatment of hepatic fibrosis?
... reverse hepatic fibrosis, ...on hepatic fibrosis in an experimental non-alcoholic steatohepatitis (NASH) model ...of fibrosis in NASH model rats ...that hepatic fibrosis ...
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Mac the knife? Macrophages– the double edged sword of hepatic fibrosis
... on hepatic fibrosis between a murine model in which macrophages were depleted during the progression of fibrosis by the administration of diptheria toxin after 12 weeks of carbon tetrachlo- ride (CCl ...
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Cholestasis with Hepatic Fibrosis secondary to Sarcoidosis - A Case Report
... cholestasis has been reported frequently in the literature from outside Pakistan 8-10 . Necroinflammatory changes (as seen in our patient) have been reported in up to 41% of the patients 9 . Hepatic ...
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REVIEW ARTICLE Review of diagnostic techniques of hepatic fibrosis
... proteins are then processed through mass spectrometry technique, which detects the peptide mass and amino acid sequence. Hepatic fibrosis in advanced stages leads to changes in structural proteins. This ...
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Babao Dan attenuates hepatic fibrosis by inhibiting hepatic stellate cells activation and proliferation via TLR4 signaling pathway
... aggravate hepatic fibrosis ...attenuating fibrosis not by inhibited the absorption of LPS, but through blocking TLR4 signaling pathway ...of hepatic stellate cells activated by LPS can be ...
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Gaucher’s Disease and Fatal Hepatic Fibrosis Despite Prolonged Enzyme Replacement Therapy
... clinical data suggesting the best strategy in case of hepatic fibrosis. A bone marrow transplant may de- finitively cure type 1 GD; owing to the risk, which is probably still higher in patients with ...
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Original Article Blockade of IGFBPrP1 attenuates canine hepatic fibrosis induced by thioacetamide via inhibition of hepatic stellate cell activation
... Rodent models with multiple advantages have revolutionized our ability to understand human diseases. However, the average rate of final translation from lab findings in rodent mo- dels to practice in clinical trials is ...
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Factors associated with severity of hepatic fibrosis in people with chronic hepatitis C infection
... whom hepatic fibrosis score and time of HCV exposure were recorded, and all patients with hepatic fibrosis score with no regard to time of HCV ...a hepatic fibrosis score ...
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THE RELATION OF HEPATIC FIBROSIS TO CONCENTRATION OF BILIRUBIN IN THE SERUM IN CONGENITAL ATRESIA OF THE BILIARY TRACT
... in favor of making the diagnosis as early as possible are the large amount of hepatic fibrosis in the first 2 months after birth in some infants with atresia of the bile ducts, and the f[r] ...
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Protective effects of Liuweiwuling tablets on carbon tetrachloride induced hepatic fibrosis in rats
... preventing hepatic fibrosis represents an important strategy for the treatment of chronic liver ...treat hepatic fi- brosis ...mediate hepatic fibrosis, and these agents have not yet ...
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Relationship of serum vitamin D with hepatic fibrosis in patients with chronic hepatitis C
... is a few studies from India in available literature depicting the association of vitamin D levels with liver fibrosis. The aims of the present study were to ascertain whether vitamin D deficiency has any role in ...
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IRF5 governs liver macrophage activation that promotes hepatic fibrosis in mice and humans
... prevents hepatic fibrosis in ...and fibrosis, we generated MKO mice as previously described ...in hepatic macrophages of MKO mice was confirmed by IHC, immunoblot and qRT-PCR (Figure 3A and ...
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Gaucher’s Disease and Fatal Hepatic Fibrosis Despite Prolonged Enzyme Replacement Therapy
... clinical data suggesting the best strategy in case of hepatic fibrosis. A bone marrow transplant may de- finitively cure type 1 GD; owing to the risk, which is probably still higher in patients with ...
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Hepatic steatosis in patients with HIV Hepatitis C Virus coinfection: is it associated with antiretroviral therapy and more advanced hepatic fibrosis?
... liver fibrosis in HIV-HCV coin- fected patients remain ...attenuate hepatic fibrosis in this cohort especially if patients receive HAART (rather than NRTI or sequential therapy) at onset, and if ...
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