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hepatic inflammation

Original Article Hepatic steatosis causes induction of the chemokine RANTES in the absence of significant hepatic inflammation

Original Article Hepatic steatosis causes induction of the chemokine RANTES in the absence of significant hepatic inflammation

... assess hepatic steatosis [35,36], it has to be considered that the reliable threshold is approximately 30% fat in the he- patic tissue ...had hepatic steatosis below the US- detection ...significant ...

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Resuscitation fluid composition affects hepatic inflammation in a murine model of early sepsis

Resuscitation fluid composition affects hepatic inflammation in a murine model of early sepsis

... on hepatic leukocyte ...most hepatic cytokines measured in this study, further supporting that resuscitating with albumin does not have a significant effect on hepatic inflammation during ...

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Critical roles of TRAIL in hepatic cell death and hepatic inflammation

Critical roles of TRAIL in hepatic cell death and hepatic inflammation

... in hepatic cell death and hepatic diseases is not ...mediate hepatic cell ...that hepatic cell death in vivo was dramatically reduced in TRAIL-deficient mice and mice treat- ed with a blocking ...

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Western diet enhances hepatic inflammation in mice exposed to cecal ligation and puncture

Western diet enhances hepatic inflammation in mice exposed to cecal ligation and puncture

... Background: Obese patients display an exaggerated morbidity during sepsis. Since consumption of a western-style diet (WD) is a major factor for obesity in the United States, the purpose of the present study was to ...

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Hepatic iron storage is related to body adiposity and hepatic inflammation

Hepatic iron storage is related to body adiposity and hepatic inflammation

... chronic inflammation and oxi- dative stress; due to macrophage recruitment into adi- pose tissue and release of pro-inflammatory cytokines through various ...alleviate inflammation and ROS production [24, ...

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Correlation between hepatic human males absent on the first (hMOF) and viral persistence in chronic hepatitis B patients

Correlation between hepatic human males absent on the first (hMOF) and viral persistence in chronic hepatitis B patients

... for hepatic inflammation or ...that hepatic damage is considered to be caused by host cellular immunity against HBV infected hepatocytes, rather than the direct HBV cytopathic effect [30], or that ...

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Cathepsin B inactivation attenuates hepatic injury and fibrosis during cholestasis

Cathepsin B inactivation attenuates hepatic injury and fibrosis during cholestasis

... injury, inflammation, and fibrogenesis after bile duct ligation ...(a) hepatic inflammation, as assessed by transcripts for CXC chemokines and neutrophil infiltration, and (b) fibrogenesis, as ...

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Magnetic Resonance Elastography for Liver Fibrosis in Methotrexate Treatment

Magnetic Resonance Elastography for Liver Fibrosis in Methotrexate Treatment

... Current guidelines suggest further evaluation including liver biopsy based on the frequency of abnormal AST values during one year (5/9) [2]. In our study, of the four patients with an abnormal mean liver stiffness value ...

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Original Article Propofol alleviates hepatic ischemia/reperfusion injury via the activation of the Sirt1 pathway

Original Article Propofol alleviates hepatic ischemia/reperfusion injury via the activation of the Sirt1 pathway

... on hepatic inflammation and oxidative stress, blood and hepatic samples from each group were collected after reperfusion for 4 ...reduces hepatic I/R ...

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Kupffer-derived matrix metalloproteinase-9 contributes to liver fibrosis resolution

Kupffer-derived matrix metalloproteinase-9 contributes to liver fibrosis resolution

... Although KC-derived MMP9 has been reported to play an important role in various forms of liver injury [17-19], its effect on fibrosis resolution is largely unknown. In this study, we employed the liver fibrotic model of ...

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The accuracy of the report of hepatic steatosis on ultrasonography in patients infected with hepatitis C in a clinical setting: A retrospective observational study

The accuracy of the report of hepatic steatosis on ultrasonography in patients infected with hepatitis C in a clinical setting: A retrospective observational study

... with hepatic inflammation and ...histologic inflammation. The ability of ultrasonography to accurately detect hepatic steatosis is questionable outside of a controlled research setting, as ...

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The role of inflammation in lipid metabolism

The role of inflammation in lipid metabolism

... Besides hepatic inflammation, HFD feeding induces adipose tissue inflammation, characterized by macrophage infiltration and production of proinflammatory cytokines that play a causal role in the ...

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Dynamics of Th9 cells and their potential role in immunopathogenesis of murine schistosomiasis

Dynamics of Th9 cells and their potential role in immunopathogenesis of murine schistosomiasis

... of hepatic fibrosis due to carbon tetrachloride (CCl4), the percentages of splenic Th9 cells also ascended rapidly and peaked at the 6th week, meanwhile serious hepatic inflammation occurred around ...

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Vascular adhesion protein 1 promotes liver inflammation and drives hepatic fibrosis

Vascular adhesion protein 1 promotes liver inflammation and drives hepatic fibrosis

... by hepatic leukocyte accumulation in the form of ...that hepatic VAP-1 expression is increased in patients with chronic liver disease and that serum sVAP-1 levels are elevated in patients with NAFLD ...

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Anti Inflammatory Pre Treatment to Reduce Mobilization Induced Liver Inflammation in Mice: Novel Model to Study Liver Injury

Anti Inflammatory Pre Treatment to Reduce Mobilization Induced Liver Inflammation in Mice: Novel Model to Study Liver Injury

... liver inflammation after mobiliza- ...liver inflammation before [7], we were keen to study the effect of anti-TNF- α (Infliximab) [8] pre-treatment in mice undergoing gentle liver ...acute hepatic ...

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Original Article Specific chemokines CCL2 and CCL17 are correlated with hepatic necro-inflammation in chronic hepatitis B patients with normal/mildly elevated alanine aminotransaminase levels

Original Article Specific chemokines CCL2 and CCL17 are correlated with hepatic necro-inflammation in chronic hepatitis B patients with normal/mildly elevated alanine aminotransaminase levels

... chronic hepatic inflammation for each liver specimen ...portal inflammation, no lobular inflammation), G1 (portal inflammation, lobular inflammation but no necrosis), G2 (mild ...

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Original Article Inflammation and cancer: inhibiting the progression of residual hepatic VX2 carcinoma by anti-inflammatory drug after incomplete radiofrequency ablation

Original Article Inflammation and cancer: inhibiting the progression of residual hepatic VX2 carcinoma by anti-inflammatory drug after incomplete radiofrequency ablation

... Cyclooxygenase-2 (COX-2) converts arachidonic acid to prostaglandins, which in turn induce inflammatory reactions in damaged tissues [34]. COX-2 is also involved in carcinogenesis pathways in many organs. It has been ...

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Concomitant administration of atorvastatin with N-acetylcysteine mitigates liver injury and steatosis in experimental non-alcoholic fatty liver disease

Concomitant administration of atorvastatin with N-acetylcysteine mitigates liver injury and steatosis in experimental non-alcoholic fatty liver disease

... N-Acetylcysteine (NAC) is a glutathione precursor, limits the reactive oxygen species that causes hepatocellular injury and its antioxidative properties have been tested clinically and in animal models of NAFLD (Ali et ...

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A lipid-rich gestational diet predisposes offspring to nonalcoholic fatty liver disease: a potential sequence of events

A lipid-rich gestational diet predisposes offspring to nonalcoholic fatty liver disease: a potential sequence of events

... Genistein, a soy isoflavone found in soybeans, has received more consistent favorable literature reviews than n-3 PUFAs. When provided concurrently with a maternal HF diet and comprising 0.2% (by weight) of total ...

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Autophagy: a new target for nonalcoholic fatty liver disease therapy

Autophagy: a new target for nonalcoholic fatty liver disease therapy

... Although autophagy plays essential roles in HSC activa- tion and fibrosis promotion, its effect on antifibrosis and col- lagen degradation should not be neglected. In α -1-antitrypsin deficiency, a disease in which the α ...

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