hepatic lipase
Abnormalities in hepatic lipase in chronic renal failure: role of excess parathyroid hormone
... Post-heparin hepatic lipase activity is reduced in chronic re- nal failure ...examined hepatic lipase metabolism in normal, 6-wk-old CRF rats, CRF-PTX (parathyroidecto- mized) rats, and CRF ...
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High density lipoprotein2 Relationship of the plasma levels of this lipoprotein species to its composition, to the magnitude of postprandial lipemia, and to the activities of lipoprotein lipase and hepatic lipase
... Lipoprotein lipase (LPL) activity in postheparin plasma of 38 normolipidemic volunteers was related to the magnitude of postprandial lipemia after a fat meal, to triglyceride content of high density lipoprotein2 ...
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Variation at the hepatic lipase and apolipoprotein AI/CIII/AIV loci is a major cause of genetically determined variation in plasma HDL cholesterol levels
... hepatic lipase and apolipoprotein AI/CIII/AIV accounted for 25 and 22%, respectively, of the total interindividual variation in plasma HDL-C ...the hepatic lipase and the apolipoprotein ...
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Hepatic lipase expression in macrophages contributes to atherosclerosis in apoE deficient and LCAT transgenic mice
... Hepatic lipase (HL) has a well-established role in lipoprotein metabolism. However, its role in ath- erosclerosis is poorly understood. Here we demonstrate that HL deficiency raises the proathero- genic ...
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Postprandial lipemia A key for the conversion of high density lipoprotein2 into high density lipoprotein3 by hepatic lipase
... subjects, HDL2 levels ranged widely from 4.7 to 151.7 mg/dl plasma. HDL2 were isolated in the postabsorptive (pa) state and in the postprandial (pp) state, i.e., 7 h after ingestion of a standard fatty meal. In going ...
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Hepatic lipase gene therapy in hepatic lipase deficient mice Adenovirus mediated replacement of a lipolytic enzyme to the vascular endothelium
... Hepatic lipase (HL) is an endothelial-bound lipolytic en- zyme which functions as a phospholipase as well as a tri- acylglycerol hydrolase and is necessary for the metabolism of IDL and ...• hepatic ...
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Positive association of the hepatic lipase gene polymorphism c.514C > T with estrogen replacement therapy response
... Background: Hepatic lipase (HL), an enzyme present in the hepatic sinusoids, is responsible for the lipolysis of lipoproteins. Human HL contains four polymorphic sites: G-250A, T-710C, A-763G, and ...
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Association of variation in hepatic lipase activity with promoter variation in the hepatic lipase gene The LOCAT Study Invsestigators
... the hepatic lipase (HL) gene ( LIPC ) and variation in posthep- arin HL activity and fasting serum lipoproteins were evalu- ated in 395 male Finnish coronary heart disease patients with HDL cholesterol ...
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Key words
... A high-carbohydrate (high-CHO) diet in- duces a multitude of biochemical changes on lipid metabolism. After digestion, carbohydrates can be converted into triacylglycerols and cholesterol mainly in the liver. ...
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Lipoprotein Metabolism during Acute Inhibition of Hepatic Triglyceride Lipase in the Cynomolgus Monkey
... enzyme hepatic triglyceride lipase was investigated in a primate model, the cynomolgus ...postheparin hepatic lipase fully inhibited cynomolgus monkey posttheparin plasma hepatic ...
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Characterization of lipase activities in obese Pima indians Decreases with weight reduction
... lipoprotein lipase and postheparin hepatic and lipoprotein lipase activities have been measured in a group of 21 Pima Indian males over a wide range of body weight to determine the relationship ...
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Inhibition of endothelial lipase causes increased HDL cholesterol levels in vivo
... Endothelial lipase (EL) is a recently discovered mem- ber of the triglyceride lipase gene family (1, ...lipoprotein lipase (LPL) and hepatic lipase (HL), both of which are known to ...
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... human hepatic lipase (LIPC) gene encodes HL, an enzyme involved in lipoprotein metabolism and regulation ...between hepatic lipase and CAD has been controversial ...
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Physiogenomic analysis of weight loss induced by dietary carbohydrate restriction
... six lipase genes listed in order of genetic association significance, as follows: LIPF gastric lipase, LIPC hepatic lipase, LIPG endothelial lipase, LIPE hormone-sensitive ...
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The syndecan family of proteoglycans Novel receptors mediating internalization of atherogenic lipoproteins in vitro
... by hepatic lipase has been shown to require cell-surface HSPGs, presumably owing to bridging ...(31). Hepatic lipase–facilitated catabolism of rem- nant lipoproteins has been demonstrated in ...
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Effect of heparin induced lipolysis on the distribution of apolipoprotein e among lipoprotein subclasses Studies with patients deficient in hepatic triglyceride lipase and lipoprotein lipase
... hepatic lipase or of lipoprotein lipase and compared them with normal ...familial hepatic triglyceride lipase deficiency (n = 2) differ markedly from normal in that fraction II is the ...
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Abnormalities in very low, low and high density lipoproteins in hypertriglyceridemia Reversal toward normal with bezafibrate treatment
... Post-heparin plasma lipoprotein lipase and hepatic lipase in normal subjects and in patients with hypertriglyceridaemia: correlation to sex, age and various parameters of triglyceride me[r] ...
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The therapeutic efficacy of intensive medical therapy in ameliorating high-density lipoprotein dysfunction in subjects with type two diabetes
... reducing hepatic syn- thesis of apoA-1 [11], replacing apoA-1 and paraoxonase (PON1) with serum amyloid A (SAA) [12], and post- translation modification (PTM) of apoA-1 [13]; concur- rently, HDL enrichment in ...
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Lipoprotein lipase activity and mass, apolipoprotein C-II mass and polymorphisms of apolipoproteins E and A5 in subjects with prior acute hypertriglyceridaemic pancreatitis
... Our study focussed on the analysis of post-heparin lipo- protein-lipase activity and the level of apolipoprotein C-II in persons who had survived at least one episode of hyper- triglyceridaemic pancreatitis in ...
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Association between skeletal muscle mass and serum concentrations of lipoprotein lipase, GPIHBP1, and hepatic triglyceride lipase in young Japanese men
... and lipase-associated protein were determined during periods wherein they were not under dietary restrictions or were not undergoing hard prac- tices for a ...
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